Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion حسب Al-Dimassi, Saleh

"…Cell invasion is a complex process that replies on many signaling pathways including the mitogen-activated protein (MAP) kinase (MAPK). In many cell lines, the use of MAPK-targeted drugs proved to be a potential method to inhibit cancer cell motility. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

miRNA-dependent regulation of STIM1 expression in breast cancer حسب Rashmi P. Kulkarni (18618634)

"…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …"

The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis حسب Mroueh, MA

"…We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Simulation of the size-composition distribution of atmospheric nanoparticles over Europe حسب David Patoulias (4722960)

"…The ground level concentrations of particles with a diameter larger than 100 nm (N100) were reproduced with a daily normalized mean error of 40 % and a daily normalized mean bias of −20 %. …"

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma حسب Peter Kubatka (11008854)

"…In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …"

Exploring Sustainable Strategies for Shelter Design at Refugee Camps: The Case of Domiz 1 Refugee Camp in Iraq حسب AL AMEEN, FARAH

"…As a result, the proposed strategy provides an opportunity for personalization and deepens the refugees’ sense of belonging and dignity. Furthermore, a 42% decrease in cooling loads, and 31% decrease in heating loads was achieved by using the proposed wall panel, the sunspace during winter, and the roof canopy during winter, in comparison to the baseline case, the UNHCR tent.…"
احصل على النص الكامل

The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis حسب Daaboul, Hamid E.

"…β-2-himachalen-6-ol (HC), a novel sesquiterpene derived from Lebanese wild carrot, was shown to possess a remarkable anticancer activity. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf) حسب Connor, Izumi

"…CO2 is lost from the Gulf due to gas exchange, decreasing DIC, and reducing pCO2 to 464 μatm, similar to that observed. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Portfolio Selection Problem Using CVaR Risk Measures Equipped with DEA, PSO, and ICA Algorithms حسب Abdelouahed Hamdi (14158899)

"…It was found that when solving the Mean-CVaR model with evolutionary algorithms, the risk decreased. …"

The Effects of Local Aggregates on the Mechanical Properties of Engineered Cementitious Composites (ECC) حسب Obied, Michel

احصل على النص الكامل

Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study حسب Zeana, Samir AlKudsi

"…Participants had shown moderate resilience (mean score: 27.64 (SD = 8.31)) and their mean score fear of COVID19 was 15.67 (SD = 6.54). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Impact of staying at home measures during COVID-19 pandemic on the lifestyle of Qatar’s population: Perceived changes in diet, physical activity, and body weight حسب Muna Abed Alah (14779534)

"…Participants reported increased sitting/reclining time (1.94 h/day mean increase), screen times (2.05 h/day mean increase) with p < 0.001, and decreased exercise time (0.11 h/day mean reduction) with p < 0.001. …"

Which factor explains the life‐history of <i>Xanthium strumarium</i> L., an aggressive alien invasive plant species, along its altitudinal gradient? حسب Rafi Ullah (8146836)

"…Among climatic variables, mean yearly temperature, mean annual yearly humidity, and mean day length in hours, while in soil variables, organic matter and nitrogen percentage significantly affect the phenological and morphological stages. …"

Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response حسب Mingzhan Xue (3607649)

"…MG modification of proteins produces surface hydrophobicity through arginine-derived hydroimidazolone MG-H1 formation, with related protein unfolding and preferentially targets PDIs and chaperone pathways for modification. …"

Optimization of Electric Vehicles Wireless Charging حسب Gesrou, Abdalla

احصل على النص الكامل

The effects of a change in the point system on immigration حسب Chemin, Matthieu

"…In parallel, points for a subjective assessment of “adaptability” were decreased. In line with the initial objective, we find more French-speaking immigrants with bachelor’s degrees, and no worsening in labor market outcomes after the reform. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma حسب Abou-Ghazal, Mohamed

"…WP1066 suppressed the phosphorylation of JAK2 and phosphorylation (Tyr705) of STAT3 in all three melanoma cell lines. In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults حسب Khaddaj, Rashel

"…Results: The final sample size included 71 participants with an average age of 30.23 ±7.66and constituted of 59.2% females. The mean baseline 25(OH)D3 concentration was 16.92±7.23ng/ml in the vitamin D group and 16.44±5.91 ng/ml in the control group (p =0.76). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Recovery of business intelligence systems حسب Haraty, Ramzi A.

"…Denial of service affects the continuity of the healthcare system which in turn threatens patients’ lives, decreases the efficiency of the healthcare system and increases the operating costs of the attacked healthcare organization. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Transfer function analysis between arterial pressure and renal sympathetic nerve activity at cardiac pacing frequencies in the rat حسب Kanbar, Roy

"…Cardiac pacing slightly increased mean AP (0.8 ± 0.2 mmHg/Hz) and decreased pulse pressure (−3.6 ± 0.3 mmHg/Hz) while leaving the mean level of RSNA essentially unaltered (P = 0.680, repeated-measures ANOVA). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل