STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration حسب Ayat S. Hammad (9592374)

"…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca²⁺ entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …"

Driving simulation sickness and the sense of presence: Correlation and contributing factors حسب Mustafa Almallah (17280568)

"…Importantly, designing buildings that replicate a real-world environment could increase SP and decrease SS. Moreover, designing high quality and resolution scenarios could also increase SP, thus decreasing the severity of SS symptoms. …"

An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im... حسب Khreibi, Rima Abou

"…In terms of United Arab Emirates University (UAEU), there has been a decrease in STEM programs enrolment, while STEM graduates in UAEU has stayed steady at 1/3 STEM majors compared to 2/3 non-STEM programs. …"
احصل على النص الكامل

Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways حسب Shehaby, Wassim N.

"…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma حسب Shebaby, W.

"…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Subsarcolemmal cAMP signals monitored by cyclic nucleotide gated channels in hypertrophied cardiac myocytes حسب Abi-Gerges, Aniella

"…These results show that CNG channels allow to measure cAMP variations at the membrane in living cardiomyocytes and to detect alterations of cAMP signals during early hypertrophy.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Food purchase and eating behavior during the COVID-19 pandemic: A cross-sectional survey of Russian adults حسب Tarek Ben Hassen (15742605)

"…<p dir="ltr">The Russian government took strong containment measures to prevent the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with rigid hygiene protocols and restrictions on daily living, such as social distancing and closing businesses and schools. …"

Energy Efficient Refurbishment for Existing Office Building in UAE حسب Kalkura, Subraya

"…The other principles are to decrease the energy use and related operational expenses while to increase use of environment-friendly materials and renewable energy sources. …"
احصل على النص الكامل

Effect of StarD13 on colorectal cancer proliferation, motility and invasion حسب Nasrallah, Anita

"…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression حسب Rayanah Barnawi (8737584)

"…Herein, fascin ShRNA was used to generate stable fascin knockdown (FSCN1^KD) in the MDA-MB-231 TNBC cell line and then were subjected to comprehensive mRNA and miRNA transcriptome analysis. …"

Optical coherence tomography findings in autoimmune retinopathy حسب Abazzari, Azin

"…Macular OCT showed reduced central macular and foveal thicknesses in 6 patients (mean thickness 143 ± 30 μm and 131 ± 29 μm respectively). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Reducing terrorism with development ; the United Nations' new path. (c2009) حسب Kassis, Maria-Rita

احصل على النص الكامل
احصل على النص الكامل

Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows حسب Tohid, Adibi

"…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Boron doped silver-copper alloy nanoparticle targeting intracellular S. aureus in bone cells حسب Tahir Abdulrehman (8697696)

"…The binding of the targeting nanoparticles to infected osteoblasts as well as the visualization of live/dead bacteria due to treatment was carried out using fluorescence microscopy. …"

Wales’ tourists not a burden for local healthcare حسب Nature Research (16552612)

"…</p><p>Instead, they found that Welsh residents were responsible for the vast majority of unintentional injury presentations to the emergency department. They also found a decrease in non-resident presentations between 2006 and 2014, the data range that was studied.…"

Women’s empowerment as a determinant of neonatal mortality in Sub-Saharan Africa: a narrative review focused on Nigeria حسب Joel-Medewase Victor Idowu (22155178)

"…Notably, SSA and South Asia are the regions most lagging behind the Sustainable Development Goal (SDG) 3.2, aiming for <12 neonatal deaths per 1,000 live births by 2030. Within SSA, Nigeria, the most populous country, records the highest number of neonatal deaths annually. …"

Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells حسب Gowtham Kumar Subbaraj (17807615)

"…Morphometric analysis of CAM showed that treatment with nano-formulated water-soluble kaempferol and combretastatin caused a substantial decrease in density, vessel network, branch points, and nets of CAM blood vessels. …"

Carotid artery revascularization through a radiated field حسب Lesèche, Guy

"…All patients had received previous radiation therapy within a mean interval of 10 years (range, 1-26 years), with average radiation dose of 62 Gy (range, 50-70 Gy). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Turkronicles: diachronic resources for the fast evolving Turkish language حسب Togay Yazar (22828175)

"…Despite the substantial vocabulary changes, we demonstrate that it is possible to identify old Turkish words that have the same meanings with newly coined ones using word embeddings. …"