ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder by Sara Cuvertino (18892069)

“…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …”

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2·5th and 97·5th percentile values across the draws. …”
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Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models by Mezher, Nawal

“…ACSS2 inhibition significantly reduced the expression of pro-inflammatory cytokines such as Interleukin 8 (IL-8), IL-1β, and TNF-α, and attenuated activation of NF-κB and MAPK signaling pathways, as evidenced by decreased phosphorylation of p65 and ERK/MEK. These findings highlight a pro-inflammatory role for ACSS2 in IBD and identify it as a potential therapeutic target, warranting further validation in advanced models, including patient-derived organoids and in vivo systems.…”
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Intravitreal adalimumab in active noninfectious uveitis by Hamam, Rola N.

“…Results: Six out of 7 patients (12 of 13 eyes) completed 26 weeks of treatment. One patient (1 eye) failed treatment. Seven out of 12 eyes had improvement of ≥2 ETDRS lines. …”
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Breast cancer cells and bone marrow mesenchymal stromal cells by Faour, Wissam H.

“…Co-cultures with either MG-63 cells or MSCs induced OPG and MMP-2 in both tumor cell lines. Interestingly, conditioned medium from co-cultures of MSCs and MDA-MB-231 cells significantly decreased the proliferation of activated T lymphocytes which was reversed by addition of anti-OPG antibodies to the co-cultures. …”
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Run Rules-Based EWMA Charts for Efficient Monitoring of Profile Parameters by Ali Yeganeh (16624998)

“…<p>In usual quality control methods, the quality of a process or product is evaluated by monitoring one or more quality characteristics using their corresponding distributions. …”

Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models by Ben Romdhane, Haifa

“…Furthermore, results demonstrated that the probability of severe damage increases with decreasing water oxygenation and with increasing temperature, light, salinity, acidity and nutrient levels. …”
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Performance Analysis of FSO Communications With Diversity Methods by Abou-Rjeily, Chadi

“…By comparing the MIMO and cooperative methods with point receivers, we reach the central result that it is always better, from a diversity gain point of view, to add more apertures to the source and destination rather than adding more relays in their vicinity despite the fact that the fading variance along FSO links decreases with the distance. For receivers that implement aperture averaging, we derive conditions under which MIMO techniques are unconditionally better than cooperative techniques with any network topology.…”
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α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain by Eid, Fady

“…Major depression and anxiety are one of the most common mental disorders worldwide. …”
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A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats by Zeeni, Nadine

“…Brain-derived neurotrophic factor (BDNF) and its TrkB receptor play critical roles in the synaptic activity and plasticity of mature neurons and enhance adult neurogenesis. …”
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Detecting attacks in a cluster based QOS-OLSR protocol. (c2014) by Sanadiki, Hiba

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Secrecy Performance of a RIS-Assisted Wireless Network: A Comprehensive Analysis Under Outdated CSI by Tasneem Alshamaseen (22392382)

“…To this end, the secrecy outage probability (SOP) metric is derived under the presence of outdated CSI (aging) at the RIS controller, considering four scenarios based on the availability of direct links between the transmitter and both receivers (i.e., the legitimate one and the eavesdropper). …”

Do Older Adults with Multimorbidity Meet the Recommended Levels of Physical Activity? An Analysis of Scottish Health Survey by Ahmad Salman (3173418)

“…Also, meeting recommended PA decreased with age [OR 0.92 (95% CI 0.90–0.94)] and body mass index [OR 0.93 (95% CI 0.91–0.95]; but increased per additional portion of fruit and vegetables taken [OR 1.19 (95% CI 1.12–1.25)] and with increase in well-being scale score [OR 1.05 (95% CI 1.03 to 1.06)]. …”

Fetoplacental transmission and placental response to SARS-CoV-2: Evidence from the literature by Henry C. Ezechukwu (13253406)

“…The results indicated that SARS-CoV-2 induces placenta inflammation, and placenta susceptibility to SARS-CoV-2 decreases across the pregnancy window. Thus, SARS-CoV-2 infection in early pregnancy may adversely affect the developing fetus.…”

Orofacial Clefts by El Baba, Nada

“…We found no significant differences in the proliferative abilities of the patient-derived cells and the healthy cells. The striking difference in behavior was related to cell migration, whereby the patient-derived cells showed decreased motility, increased adhesion, and a general loss of polarity compared to the healthy cells. …”
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Direct Oral Anticoagulants Compared to Warfarin in Patients with Intermediate‐ to High‐Risk Pulmonary Embolism: A Systematic Review and Meta‐Analysis by Mohamed Nabil Elshafei (9960500)

“…Pooled odds ratios were derived from the included studies using the random‐effects model. …”

A Risk-Based Multi-Objective Modeling Approach to the Preventive Maintenance Process of Roof Waterproofing System at Airports by Shehab, Bahaa

“…The purpose of this study is to: (a) determine current waterproofing systems and components of concrete roofs at airports, (b) explore frequently used techniques to design optimal preventive maintenance policies, and (c) derive an optimal preventive multi-objective risk-based maintenance strategy via simulation that can diminish failure costs, thereby decreasing the system’s overall maintenance costs. …”
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A Risk-Based Multi-Objective Modeling Approach to the Preventive Maintenance Process of Roof Waterproofing System at Airports by Shehab, Bahaa

“…The purpose of this study is to: (a) determine current waterproofing systems and components of concrete roofs at airports, (b) explore frequently used techniques to design optimal preventive maintenance policies, and (c) derive an optimal preventive multi-objective risk-based maintenance strategy via simulation that can diminish failure costs, thereby decreasing the system’s overall maintenance costs. …”
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Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells by Tawil, Mirna

“…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …”
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Error probability of coded STBC systems in block fading environments by Zummo, S.A.

“…In this letter, a union bound on the error probability of coded multi-antenna systems over block fading channels is derived. The bound is based on uniform interleaving of the coded sequence prior to transmission over the channel. …”
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