The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …"

STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration حسب Ayat S. Hammad (9592374)

"…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …"

Road safety and traffic medicine in Iran: Achievements and challenges حسب A. Motevalian (19807242)

"…The number of annual fatalities, which had been on the rise for several decades, reached to the maximum number of over 27500 deaths in 2005. The number decreased to 23000 in 2010 and less than 18000 in 2013. …"

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant حسب Lei Zhang (38117)

"…It is observed that the flow velocity decreases with the increase in the Hartmann number that signifies the magnetic field. …"

Factors Associated with Meeting Current Recommendation for Physical Activity in Scottish Adults with Diabetes حسب Ahmad Salman (3173418)

"…Furthermore, meeting the recommended physical activity levels decreased with age (OR 0.96; 95% CI 0.95–0.97), having a longstanding illness (OR 0.56; 95% CI 0.34–0.93) and body mass index (OR 0.94; 95% CI 0.92–0.97), but increased with higher fruit and vegetable intake (OR 1.16; 95% CI 1.07–1.25) and mental wellbeing (OR 1.04; 95% CI 1.02–1.06). …"

A Novel Technique for Detecting Underground Water Pipeline Leakage Using the Internet of Things حسب Ahmad Abusukhon (19418644)

"…This expense can be significantly decreased using an effective early water leak detection system. …"

Influence of co-current vapor flow on falling film over horizontal tube حسب Furqan Tahir (14429547)

"…The vapor flow exerts external force on falling film and affects film hydrodynamics, heat and mass transfer. This study focuses on analyzing the effects of co-current vapor flow on falling film distribution and hydrodynamics. …"

Do Older Adults with Multimorbidity Meet the Recommended Levels of Physical Activity? An Analysis of Scottish Health Survey حسب Ahmad Salman (3173418)

"…Also, meeting recommended PA decreased with age [OR 0.92 (95% CI 0.90–0.94)] and body mass index [OR 0.93 (95% CI 0.91–0.95]; but increased per additional portion of fruit and vegetables taken [OR 1.19 (95% CI 1.12–1.25)] and with increase in well-being scale score [OR 1.05 (95% CI 1.03 to 1.06)]. …"

The Effects of Spirulina Supplementation on Cardiometabolic Risk Factors: A Narrative Review حسب Sara Sokary (17337724)

"…Spirulina was effective in reducing body weight, body mass index, and waist circumference, with a potential dose-dependent effect. …"

Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression حسب Rayanah Barnawi (8737584)

"…Herein, fascin ShRNA was used to generate stable fascin knockdown (FSCN1^KD) in the MDA-MB-231 TNBC cell line and then were subjected to comprehensive mRNA and miRNA transcriptome analysis. …"

Detailed organic characterization of process water to evaluate reverse osmosis membrane fouling in industrial wastewater treatment حسب Minier-Matar, Joel

"…The organic fouling was confirmed by mass balance calculations on the bench scale experiments as well as Fourier Transform Infrared (FTIR) analysis on the membrane coupons. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS حسب Anna Halama (545988)

"…IS was lower in PCOS (p < 0.001) and was further decreased by the lipid infusion in both PCOS and controls. …"

Exploring the LDHC Interactome as Novel Candidate Therapeutic Targets to Advance Breast Cancer Precision Medicine حسب Mariam Ahmed Amin Mohamed Elesnawy (21547187)

"…Immunoprecipitation (IP), followed by mass spectrometry (IP-MS) of <i>LDHC</i> stably silenced MDA-MB-468 breast cancer cells identified three potential LDHC binding partners with reported roles in genomic integrity and cancer: TUBA1B, PKM2 and hnRNPM. …"

Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome حسب Abu Saleh Md Moin (6189512)

"…Cohorts were age matched, though PCOS had elevated body mass index (p < 0.001), insulin (p < 0.001) and C-reactive protein (CRP) (p < 0.0001). …"

The promise of tirzepatide: A narrative review of metabolic benefits حسب Sara Sokary (17337724)

"…Furthermore, limited evidence showed that lost body weight may be primarily due to fat mass reduction. Tirzepatide also significantly decreased food intake, reduced overall appetite scores and increased fasting visual analog scale scores for satiety and fullness across different clinical trials. …"

Chromogranin A‐positive hormone‐negative endocrine cells in pancreas in human pregnancy حسب Abu Saleh Md Moin (6189512)

"…</p> <h2>Conclusions</h2> <p>Our findings of no increase in CPHN cell frequency in pancreas of pregnant women suggest that this potential β-cell regenerative mechanism is not that by which the increased β-cell mass of pregnancy is achieved. However, an increase in the percentage of clustered β-cells was found in pregnancy, with decreased frequency of other endocrine cells in clusters, suggesting a compensatory shift from other pancreatic endocrine cell types to β-cells as a mechanism to meet the increased insulin demands of pregnancy.…"

Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study حسب Zlatan Zvizdic (9212371)

"…The most common symptoms were pain (abdominal and inguinal) and inguinal mass with no palpable testis in the ipsilateral hemiscrotum. …"

Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants حسب Snigdhendubala Pradhan (9872262)

"…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …"

Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient حسب Iman Hawari (12561958)

"…LRBA was knocked down using siRNA in MIN6 cell line to investigate the role of LRBA in β-cells in more details. …"

Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study حسب Obaidullah Zafar (17910572)

"…These findings highlight the need for individualized IV iron therapy as a first-line treatment in young healthy patients to improve outcomes and optimize healthcare resources.…"