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Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery
منشور في 2010"…This study shows that US causes more release of drug at the targeted tumor. © 2010 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 99:3122–3131, 2010…"
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283
miRNA-dependent regulation of STIM1 expression in breast cancer
منشور في 2019"…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …"
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Oxandrolone Treatment in Adults with Severe Thermal Injury
منشور في 2009"…Muscle protein catabolism in patients with severe thermal injury is the result of stress-induced increased release of cytokines and counterregulatory hormones. …"
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285
Leaching Mechanisms of Cr(VI) from Chromite Ore Processing Residue
منشور في 2007"…At low pH ( <1.5), Cr(III) solid phases and the oxides responsible for Cr(VI) adsorption dissolve and release Cr(III) and Cr(VI) into solution.…"
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286
Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System
منشور في 2017"…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…"
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287
Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms
منشور في 2024"…This improvement led to decreased warranty claims, cost reductions, and enhanced product longevity, ultimately reinforcing the company's commitment to delivering high-quality products that exceed the customer's expectations. …"
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288
Power System Transient Stability Assessment Based on Machine Learning Algorithms and Grid Topology
منشور في 2023"…Features of transmission line maintenance were used to increase accuracy of estimation. …"
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289
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Novel proteins implicated in lipid metabolism disorders
منشور في 2016"…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …"
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Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
منشور في 2020"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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293
Vertical Distribution of Phosphorous Fractions and Bioavailability of the Nutrient in the Southern Indian Ocean
منشور في 2022"…The lower iron bound P fraction at specific depths was attributed to the nature of Fe minerals present within sediments. Decreased level of organic phosphate fraction was due to mineralization. …"
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Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
منشور في 2014"…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …"
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295
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
منشور في 2011"…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …"
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296
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
منشور في 2013"…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…"
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297
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Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch
منشور في 2025"…VAMP7 knockout also decreased IL-4 and LTC4 release from basophils. Additionally, OSM downregulated barrier proteins and upregulated pruriceptors in keratinocytes; however, these effects were reversed by SC144, which restored skin barrier function in AIF without affecting itch response in either model. …"
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299
The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
منشور في 2023"…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …"
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STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
منشور في 2023"…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …"