Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) حسب Khalil, Nathalie

"…In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. Sensitivity to arginine depletion using HuArgI (Co)-PEG5000 was evident in all of the tested PC cell lines with IC50 values in the pM range at 72 hours following treatment. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership حسب JASIM, ARIF FADHEL AHMED

"…The highest level of leaders makes fewer conceptual errors, and these errors increase as the levels decrease. Furthermore, just as there are essential conceptual skills to lead change, there are also misconceptions. …"
احصل على النص الكامل

1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH حسب Elhilali, Mostafa

"…In the Phase I study, mean IPSS showed a decrease of 6.5 points (34%), mean QoL a decrease of 2 points (44%) and mean prostate volume a decrease of 5.5 cc (13%) at 12-months compared to screening. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells حسب Zgheib, Perla

"…Upon treatment, a pronounced decrease in cancer cell motility was observed in the 4 cell lines. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A pathway to 25% reduction in greenhouse gas emission by 2030 using GIS-Based multi-criteria decision making for renewables, date palm (phoenix dactylifera), and carbon credits: a... حسب Hazrat Bilal (7367477)

"…<p dir="ltr">Qatar is making concerted efforts at the national level to decrease anthropogenic greenhouse gas emissions. The country has set its National Determined Contribution (NDC) in line with the Paris Agreement to reduce its overall emissions by 25% by the year 2030. …"

The antioxidant and anticancer effects of Wild Carrot oil extract حسب Shebaby, Wassim Nasri

"…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013) حسب Zgheib, Perla Z.

"…Upon treatment, a pronounced decrease in cancer cell motility was observed in the four cell lines used. …"
احصل على النص الكامل
احصل على النص الكامل

Cryomyolysis, a new procedure for the conservative treatment of uterine fibroids حسب Zreik, Tony

"…Normal uterine volume ranged from 35.6 to 548.7 ml preoperatively and 45.1 to 729.6 ml postoperatively (mean increase 40%); however, myoma volume showed a mean decrease of 6% (range-87-28%). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis حسب Charbel Abi Khalil (14150028)

"…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …"

Using integrated control methodology to optimize energy performance for the guest rooms in UAE hospitality sector حسب AlFaris, Fadi

"…This research was conducted to measure, evaluate and increase the energy efficiency in 4 and 5 star luxury hotels in UAE. …"
احصل على النص الكامل

Using integrated control methodology to optimize energy performance for the guest rooms in UAE hospitality sector حسب AlFaris, Fadi

"…This research was conducted to measure, evaluate and increase the energy efficiency in 4 and 5 star luxury hotels in UAE. …"
احصل على النص الكامل

The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function حسب MUBARAK, ALIA MARJAN

"…These mega-projects may include the construction of major buildings, roads, railway lines and airports. The success of these public initiatives may create the course for the government to decrease its reliance on other sectors. …"
احصل على النص الكامل

Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells حسب Al Sayyed, Fatima

"…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells حسب Shebaby, Wassim N.

"…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension حسب Thiruveni Ramkumar (17075051)

"…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …"

Rescue cerclage حسب Khoury, Alfred

"…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The effect of bullying-themed literature on the bullying behavior of upper elementary students in Lebanon. (c2012) حسب Bazzy, Anissa

احصل على النص الكامل
احصل على النص الكامل

Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion حسب Al-Dimassi, Saleh

"…However, astrocytoma cells that were treated with LeTx showed a significant decrease in cell motility as seen by wound healing as well as random 2D motility in serum. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis حسب Mroueh, MA

"…We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy حسب Taki, Fatima

"…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل