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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
Published 2018“…Periodic based automatic cleaning showed decreases in improvement of between 164.64% to 245.34%. …”
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143
Managing Endothelial Dysfunction in COVID-19
Published 2022“…Secondary outcomes included the composite outcome of ICU admission or the need for mechanical ventilation, all-cause mortality, and the occurrence of side effects Results Of 42 randomized patients, 37 were included in the primary analysis. The mean age of the patients was 57 years; the mean BMI of study participants was 29.14. …”
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144
Blockchain, climate damage, and death: Policy interventions to reduce the carbon emissions, mortality, and net-zero implications of non-fungible tokens and Bitcoin
Published 2022“…</p><p dir="ltr">Nonetheless, many popular types of blockchain have resisted the pressure to decrease their environmental impact, including Bitcoin, whose attributed 2021 annual emissions will produce emissions responsible for around 19,000 future deaths. …”
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Total hip arthroplasty: Evolution of the use of dual mobility cups in Lebanon
Published 2018“…Recurrent dislocation, being a major reason for revision total hip arthroplasty (THA), was found to decrease significantly using dual mobility cup (DMC) compared to standard cups (SC), and that in both primary and revision THA. …”
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Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials
Published 2023“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”
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DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma
Published 2012“…Finally, we detected an increase in p-ERK in StarD13 knockdown cells, uncovering a potential link between Rho GTPases and ERK activation.…”
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COVID-19 and Anemia: What Do We Know So Far?
Published 2023“…The primary effect of these mechanisms is a decrease in circulating hemoglobin levels, reducing oxygen availability for cells. …”
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Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover
Published 2020“…The latter is linked to the recent suggestion of protein glycation in sugar signaling in plant metabolism. …”
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151
Adsorption in nanopores with finite pore walls from truncated graphene
Published 2011“…This model mimics real carbon samples better than usually used infinite pore models, whatever is the assumed pore shape (slit-like, tubular, curved etc). In particular, it allows us to account for the adsorption at the pore edges, totally neglected in infinite models. …”
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Evaluation of the Surface Integrity and Recast Layer in Electrical Discharge Turning of WC-Co Composites
Published 2024“…<div><p>Tungsten carbide (WC) and its composites are typically associated with high hardness and high wear resistance, posing challenges in conventional machining processes like turning. To address the machining difficulties of WC-Co, electrical discharge turning (EDT) was proposed. …”
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Short-term outcomes of anterior cruciate ligament reconstruction with or without lateral tenodesis or anterolateral ligament reconstruction: a retrospective cohort
Published 2023“…However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.…”
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Exploring the potential of applying Sustainable Retrofitting Policies & Regulations for existing low-rise small-scale Residential Buildings (Villas) in Dubai, UAE
Published 2020“…Green retrofit for existing buildings has now become as one of the effective options to decrease energy consumption worldwide. It is crucial to develop sustainable retrofitting policies and regulations for the existing old villas since there is lack of regulations to retrofit old existing low scale residential buildings like villas in Dubai. …”
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155
Turkronicles: diachronic resources for the fast evolving Turkish language
Published 2025“…Regarding writing conventions, we found a noticeable decrease in the use of circumflex. In addition, words ending with the letters ‘-b’ and ‘-d’ have been largely replaced by their counterparts ending with ‘-p’ and ‘-t’, respectively, although the former are still in use. …”
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Glycemic Index of commonly consumed Lebanese mixed meals and desserts
Published 2010“…The determination of the Glycemic Index (GI) and Load (GL) for mixed meals serves as a dietetic tool in meal planning to reinforce the benefits of low GI meals and decrease the physiological effects of high GI meals. …”
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Analyzing the Influence of Climate and Anthropogenic Development on Vegetation Cover in the Coastal Ecosystems of GCC
Published 2025“…Our results revealed significant changes in land cover, as seen by an increase in artificial built-up areas by 15.5% in two decades and a corresponding decrease in bareland and dense vegetation. We also observed an increase in mangrove and seagrass areas, likely due to recent conservation and afforestation efforts. …”
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Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats
Published 2017“…Here, we investigated the effects of exendin-4 or selenium administration on the expression of glucagon-like peptide-1 receptor (GLP-1R), insulin receptor substrate-1 (IRS-1), and preproinsulin in the pancreas of diabetic rats. …”
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Slater to Mott Crossover in the Metal to Insulator Transition of Nd2Ir2O7
Published 2016“…Upon cooling below the transition temperature, this compound exhibits a gap opening with an energy shift of quasiparticle peaks like a band gap insulator. The quasiparticle peaks are strongly suppressed, however, with further decrease of temperature, and eventually vanish at the lowest temperature, leaving a nondispersive flat band lacking long-lived electrons. …”
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