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  1. 361
  2. 362

    A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

    Published 2025
    “…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
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  3. 363

    The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms by Farah Karam (22330564)

    Published 2025
    “…While the incidence and mortality of CRC have decreased overall due to better screening, rates in adults under 50 have risen. …”
  4. 364

    A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats by Zeeni, Nadine

    Published 2009
    “…Brain-derived neurotrophic factor (BDNF) and its TrkB receptor play critical roles in the synaptic activity and plasticity of mature neurons and enhance adult neurogenesis. …”
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  5. 365

    Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution by Kashif Bilal (16896357)

    Published 2022
    “…Moreover, user preferences and network’s contextual information can differentiate between live and cached access patterns optimizing edge caching decisions. …”
  6. 366

    Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species by Jennifer Bruder (323066)

    Published 2022
    “…<p dir="ltr">The preservation of our planet’s decreasing biodiversity is a global challenge. Human attitudes and preferences toward animals have profound impacts on conservation policies and decisions. …”
  7. 367

    Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

    Published 2024
    “…Although mortality rates due to appendicitis decreased in all regions, there were large regional variations in the temporal trend in incidence. …”
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  8. 368

    Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar by Doua Abdelrahman (17280667)

    Published 2021
    “…<div><p>Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. …”
  9. 369

    Associating learning technology to sustain the environment through green mobile applications by Haraty, Ramzi A.

    Published 2019
    “…Thus, it presents a stepping stone towards linking learning technology while at the same time sustaining the environment.…”
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  10. 370
  11. 371

    Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF by Jabr, Vanessa

    Published 2020
    “…These positive outcomes are mediated through the induction of the expression of a growth factor, brain derived neurotrophic factor (BDNF), in the hippocampus. …”
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  12. 372

    Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman Alzu'bi (18192898)

    Published 2024
    “…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
  13. 373

    Dicarbonyl stress, protein glycation and the unfolded protein response by Naila Rabbani (291722)

    Published 2022
    “…An optimized inducer of Glo1 expression, trans-resveratrol and hesperetin combination, normalized increased MG concentration, corrected insulin resistance and decreased low grade inflammation in overweight and obese subjects. …”
  14. 374

    Resilience of UAE high-rise buildings to climate change: Impacts of projected climate changes on annual energy demands. by Sallam, Duaa

    Published 2020
    “…This study has revealed that the derived future weather files daily dry-bulb temperatures are increasing throughout the years, while the daily relative humidity ratio and global horizontal solar radiation values are marginally decreasing from the present values. …”
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  15. 375

    Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants by Snigdhendubala Pradhan (9872262)

    Published 2022
    “…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …”
  16. 376

    Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update by Maria K. Smatti (4675852)

    Published 2018
    “…EBV is highly prevalent since it affects more than 90% of individuals worldwide and has been linked to several malignancies including PTLDs, which are one of the most common malignancies following transplantation. …”
  17. 377

    Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

    Published 2025
    “…LAT2 mutations in human populations have been linked to the early onset of age‐related hearing loss and cataract growth. …”
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  19. 379

    Nicotine induces resilience to chronic social defeat stress in a mouse model of water pipe tobacco exposure by activating BDNF signaling by Khalifeh, Mohamad

    Published 2020
    “…Even though WTS initially decreased anxiety-like behaviors, prolonged exposure after the completion of CSDS significantly induced anxiety-like behaviors. …”
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  20. 380

    The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort by Ken Van Alsenoy (14150559)

    Published 2019
    “…Albeit not reaching statistical significance (P = 0.11, η<sup>2</sup> = 0.12), RE on average improved in EVA (+2.1±4.8% and +2.9±4.9%) and TPU (+0.9±5.9% and +0.9±5.3%) compared to CON at LS and HS, respectively. Braking force was decreased by 3.4±9.1% at LS and by 2.7±9.8% at HS for EVA compared to CON (P = 0.03, η<sup>2</sup> = 0.20). …”