eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways by Zvi Cramer (10742876)

“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”

Optical coherence tomography findings in autoimmune retinopathy by Abazzari, Azin

“…Macular OCT showed reduced central macular and foveal thicknesses in 6 patients (mean thickness 143 ± 30 μm and 131 ± 29 μm respectively). …”
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Dissecting the signaling pathways regulating the vascular endothelial growth factor (VEGF) in brain tumor cells. (c2017) by Nicolas, Samer Michel

“…Angiogenesis, the fabrication of neo-blood vessels (capillaries), is one of the major hallmarks of cancer and is one of the underlying mechanisms for the tumor’s aggressiveness and metastasis. …”
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …”

Total hip arthroplasty: Evolution of the use of dual mobility cups in Lebanon by Assi, Chahine

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Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats by Barakat, Ghinwa

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Expanding the donor pool by Ramos, Emilio

“…These measures may be beneficial in terms of increasing the number of donors and decreasing the waiting time. However, deviation from the standard method of cadaver donor selection is not without possible negative impact on graft survival. …”
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

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A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV by Rizk, Sandra

“…Fabry disease is an X-linked lysosomal storage disorder that leads to abnormal accumulation of glycosphingolipids due to a deficiency of alpha-galactosidase A (AGAL). …”
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Breast cancer cells and bone marrow mesenchymal stromal cells by Faour, Wissam H.

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Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells by Castellino, R.C.

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A Power Ripple Compensator for DC Nanogrids via a Solid-State Converter by Ahmad Khan (6067526)

“…This SSC is often considered as the main DC nanogrid energy control unit that is linking the nanogrid with the main utility AC grid and managing the nanogrid elements. …”

Comparing WZB117-liposome Synthesis via Thin-film Hydration and Microfluidic Methods by Yaramiree, Atena

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Design and analysis of PV fed high-voltage gain DC-DC converter using PI and NN controllers by Madisa V.G., Varaprasad

“…The modified converter contains mainly-one diode, two capacitors, and Coupled Inductor (CI). …”
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Orofacial Clefts by El Baba, Nada

“…Through whole genome sequencing, we identified three variant genes, ARHGEF18, CUL7, and EPDR1, that we could link to the cleft phenotype. Through functional assays to test the discrepancy in the behavior of both sets of cells, we assessed proliferation, motility, adhesion, and Rho GTPase activity. …”
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Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions by Vryzas, Zisis

“…The Bingham yield stress, from the low shear rate data, increased linearly with temperature, while the plastic viscosity decreased with temperature, in a manner very similar to the decrease of water viscosity with temperature. …”
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Blockchain implementations. (c2019) by Sabbagh, Ahmad Al

“…The results also show that the use of smart contracts in the implementation of the blockchain technology in the insurance sector leads to increase in efficiency and decrease in the costs, fraud and processing time.…”
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Candida albicans identification and microsatellite DNA genotyping of Lebanese clinical isolates. (c2007) by Barada, Ghyda Ali

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A clustering metaheuristic for large orienteering problems by Almiqdad Elzein (13141038)

“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”

Evaluation of pretreatment and membrane configuration for pressure-retarded osmosis application to produced water from the petroleum industry by Dareen Dardor (17052381)

“…When minimally pretreated PW (10-micron cartridge filtration (CF)) was tested in FLS mode, severe membrane fouling occurred and the PRO flux decreased by 60%. In contrast, HF modules showed <1% flux decrease under both minimal and intermediate pretreatment schemes. …”