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121
Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
منشور في 2021"…MG activated the intrinsic pathway of apoptosis, with decrease of mitochondrial and spliceosomal proteins. …"
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122
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
منشور في 2020"…</p><h3>Results</h3><p dir="ltr">Treatment of human breast cancer cells with increasing concentrations of VCX caused a significant decrease in cells growth and proliferation. This effect was associated with a significant increase in the percentage of apoptotic MDA-MB-231 cells and in the expression of the apoptotic genes, caspase 3, caspase 7, and BAX, with inhibition of antiapoptotic gene, BCL-2 levels. …"
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123
Salvia officinalis water extract: a potential hypolipidemic, hypoglycemic and anti-ulcerogenic remedy
منشور في 2010"…Assessment of liver enzyme activities (AST, ALT, LDH, ALP) revealed no hepatotoxic effects. …"
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124
Effects of ethanol addition to diesel–biodiesel blends on the CI engine characteristics
منشور في 2024"…All blends show an increase in brake mean effective pressure (BMEP) compared to B0, with the maximum enhancement observed in B10 with an average increase of 13% across all speeds. …"
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125
Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts
منشور في 2022"…The mean Hibbs angle decreased from 153.07 to 142.32° (MD = 10.54°, p < 0.001). …"
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126
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127
Analyzing the effectiveness of various coatings to mitigate photovoltaic modules soiling in desert climate
منشور في 2024"…The results indicate a decrease in light transmittance and an increase in surface coverage area over time due to dust accumulation. …"
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128
Association Between Serum Bicarbonate Levels and Prediabetes and Subclinical Inflammation in Young Healthy Adults: A Cross-sectional Study
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">A total of 825 participants with mean age 29.2 years (5.9) of which 365 (44.2%) were males. …"
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129
Using primary healthcare facilities and patients’ expectations about triage system: Patients’ perspective from multisite Jordanian hospitals
منشور في 2024"…<h3>Background</h3><p dir="ltr"> Using primary healthcare facilities can decrease the tension and workload in emergency departments (EDs). …"
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130
A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats
منشور في 2022"…In addition, the histological analysis of liver tissues proved significant injury and hepatocellular necrosis. …"
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131
An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
منشور في 2022"…The enhanced outcome was evaluated against the initial one, using PET (physiological equivalent temperature), revealing that shade separately had the highest impact on its corresponding location with a decrease of up to 16% in PET, but no decrease to the overall PET of the microclimate. …"
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132
Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
منشور في 2017"…The decrease was more significant after 72hr with an IC50 at 16mg/ml. …"
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133
A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact
منشور في 2020"…The results showed a decrease in the MSE of V<sub>mp</sub> by 74.3% (from 1.6 V to 0.411 V), and in the MSE of I<sub>mp</sub> by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …"
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134
Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …"
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135
Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie
منشور في 2017"…The percentage of persons who achieved the target of HbA1c<7% increased from .7% at baseline to 39% at week 24. Mean FPG decreased significantly from 213.7 ± 60.1 mg/dL to 120.3 ± 25.7 mg/dL (P<.001), and mean PPG from 271 ± 65.3 mg/dL to 158.1 ± 36.4 mg/dL (P<.0001). …"
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136
Effect of Urtica dioica extract intake upon blood lipid profile in the rats
منشور في 2006"…Assessment of GOT, GPT and LDH activities showed that no liver damage has occurred during the study period.…"
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137
The Kumaraswamy Pareto IV Distribution
منشور في 2021"…Various structural properties are derived including explicit expressions for the quantile function, ordinary and incomplete moments, Bonferroni and Lorenz curves, mean deviations, mean residual life, mean waiting time, probability weighted moments and generating function. …"
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138
Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromes
منشور في 2023"…<p dir="ltr">Cascade genetic testing is the process of extending genetic testing to at-risk blood relatives of individuals (called “probands”) found to carry cancer predisposition germline pathogenic gene variants. Cascade testing is critical as relatives found to carry a pathogenic gene variant have the opportunity to pursue targeted cancer risk reduction and early detection, decreasing cancer-associated morbidity and mortality. …"
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139
Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population
منشور في 2014"…People with T2DM showed a significant decrease in HDL-C levels. A strong correlation of overall hyperlipidemia with the diabetes affection status was shown (p < 0.0001). …"
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140
Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review
منشور في 2022"…Regarding the vertical jaw relation, one study reported a significant decrease in mandibular plane inclination in OC and a significant increase in OOS. …"