3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction by Masoud Forsat (14158980)

“…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. At first, simulation implemented on the comparison of the ground movements in the single and twin tunnels. …”

Flavonoids Alleviate Peripheral Neuropathy Induced by Anticancer Drugs by Manaal Siddiqui (18891637)

“…They decreased the severity of certain CIPN symptoms, such as thermal hyperalgesia and mechanical, tactile, and cold allodynia. …”

Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties by Al Zaabi, Alanood

“…Soot particles, released during diesel combustion, adversely affect human health and the environment. …”
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Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media by Kashif Rasool (2542492)

“…The biocidal performance of CS@LS was evaluated by sulfate reduction profiles coupled with analysis of extracted extracellular polymeric substances (EPS) and lactate dehydrogenase (LDH) release assays. As the nanocomposite concentration was increased from 50 to 500 µg/mL, the specific sulfate reduction rate (SSRR) decreased from 0.278 to 0.036 g-sulfate/g-VSS*day showing a relative sulfate reduction inhibition of 86.64% as compared to that of control. …”

miRNA-dependent regulation of STIM1 expression in breast cancer by Rashmi P. Kulkarni (18618634)

“…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …”

Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050 by Yingzhao, Jin

“…The disease burden of gout, LBP, and OA attributable to high BMI and gout attributable to kidney dysfunction increased, while the contribution of smoking to LBP and RA and occupational ergonomic factors to LBP decreased. Between 1990 and 2019, the slope index of inequality increased for six MSK disorders, and the relative concentration index increased for gout, NP, OA, and OMSKDs but decreased for LBP and RA. …”
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Vertical Distribution of Phosphorous Fractions and Bioavailability of the Nutrient in the Southern Indian Ocean by Muhammed Nayeem Mullungal (21385463)

“…The lower iron bound P fraction at specific depths was attributed to the nature of Fe minerals present within sediments. Decreased level of organic phosphate fraction was due to mineralization. …”

Understanding the Molecular Mechanisms of Dysglycemia in Patients with Fanconi-Bickel Syndrome by Sanaa Ali Sharari (19953093)

“…Both of the exonic mutations had overexpression of dysfunctional GLUT2 (characterized by decreased glucose uptake activity in PBMCs and mitigated glucose release activity in HEK293T). …”

Novel proteins implicated in lipid metabolism disorders by Nature Research (16552612)

“…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …”

Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch by Zhang, Wenhao

“…VAMP7 knockout also decreased IL-4 and LTC4 release from basophils. Additionally, OSM downregulated barrier proteins and upregulated pruriceptors in keratinocytes; however, these effects were reversed by SC144, which restored skin barrier function in AIF without affecting itch response in either model. …”
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Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas by Tejedor, Alejandro

“…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…”
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Migration frameworks in Africa by Alemu Asfaw Nigusie (16962900)

“…Out of this, over 21 million Africans are estimated to have lived in another African country in 2019 (IOM 2019, pp. 19, 54). …”

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

“…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …”

STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration by Ayat S. Hammad (9592374)

“…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …”

Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

“…Although mortality rates due to appendicitis decreased in all regions, there were large regional variations in the temporal trend in incidence. …”
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Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19 by Abu Saleh Md Moin (6189512)

“…Basal M1 macrophage activation was characterized by elevated levels of M1 macrophage-specific surface proteins, CD80 and CD38, and cytokines or chemokines (CXCL1, CXCL5, RANTES) released by activated M1 macrophages. Two potent M1 macrophage activation markers, CXCL9 and CXCL10, were decreased in OT2D. …”

Thermochemical splitting of CO₂ using solution combustion synthesized lanthanum–strontium–manganese perovskites by Gorakshnath Takalkar (14151135)

“…The n_O2 is decreased, and the re-oxidation capacity of each LSM perovskite is improved from cycle one to three. …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
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Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... by Haidong, Wang

“…FindingsThe global TFR decreased from 2·72 (95% uncertainty interval [UI] 2·66–2·79) in 2000 to 2·31 (2·17–2·46) in 2019. …”
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A Novel Technique for Detecting Underground Water Pipeline Leakage Using the Internet of Things by Ahmad Abusukhon (19418644)

“…This expense can be significantly decreased using an effective early water leak detection system. …”