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241
Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application
منشور في 2023"…Patient satisfaction from the provided interventions/services was determined by means of an overall rating. The correlation between practiced roles and patient satisfaction with received interventions/services was determined.…"
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242
A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country
منشور في 2022"…Among SGLT2is, empagliflozin prescriptions showed an increase from 537 (10.65%) to 2881 (34.40%) compared to dapagliflozin, which decreased by the end of 2018 from 4505 (89.35%) to 5494 (65.6%).…"
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243
Gut microbiome and Parkinson's disease: Perspective on pathogenesis and treatment
منشور في 2023"…However, it remains unclear how these mechanisms relate to sporadic PD, a more common form of PD. Both enteric and central nervous systems have been implicated in the pathogenesis of sporadic PD, thus highlighting the crosstalk between the gut and brain. …"
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244
Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis
منشور في 2022"…The overall SPE-related mortality rate was 8 % (95 % CI: 5.26–10.96). …"
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245
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
منشور في 2025"…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …"
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246
Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
منشور في 2022"…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …"
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247
Properties and Microstructure Distribution of High-Performance Thermal Insulation Concrete
منشور في 2020"…This material allows for better thermal insulation properties, thus decreasing the energy usage within the life cycle of the concrete structure. …"
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248
Exploring the LDHC Interactome as Novel Candidate Therapeutic Targets to Advance Breast Cancer Precision Medicine
منشور في 2024"…<p dir="ltr">Breast cancer remains a major health burden worldwide, being the second most commonly diagnosed cancer, and accounting for the highest cancer-related mortality rate among women. Despite decades of advances in cancer care, the identification of therapeutic targets with higher tumor specificity and favorable safety profiles remains a challenge. …"
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249
Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression
منشور في 2021"…<p dir="ltr">Recent years have witnessed major progress in development of novel therapeutic agents such as chemotherapy, targeted therapy and immune checkpoint inhibitors for breast cancer. However, cancer-related death remains high especially in triple-negative breast cancer (TNBC) due limited therapeutic options. …"
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250
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251
Novel proteins implicated in lipid metabolism disorders
منشور في 2016"…After feeding, its expression is decreased, promoting the uptake of dietary lipids in fat tissue. …"
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252
The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms
منشور في 2025"…<p dir="ltr">Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. While the incidence and mortality of CRC have decreased overall due to better screening, rates in adults under 50 have risen. …"
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253
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
منشور في 2019"…Our results revealed that these selected chalcone analogs increased dopamine levels in the rat hepatoma (H4IIE) cells and decreased the relative mRNA expression of the MAO-B enzyme.…"
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254
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
منشور في 2025"…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …"
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255
On-site workshop investment problem: A novel mathematical approach and solution procedure
منشور في 2023"…These temporary OSWs are cost-effective, leading to decreasing the material handling cost and project makespan, which indicates their important role as a part of a construction project. …"
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256
Annual performance assessment of an off‐grid and self‐sufficient sustainable climate refuge for hot arid climates
منشور في 2023"…The electrical efficiency of the photovoltaic cells decreases from 16.87% to 15.24% with an increase in cell temperature from 309 K to 315 K. …"
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257
Frugal innovation for sustainable rural development
منشور في 2023"…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …"
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258
Luspatercept's use in a patient with transfusion‐dependent beta‐thalassemia and intrathoracic extramedullary hematopoiesis (EMH)
منشور في 2024"…<h3>Key Clinical Message</h3><p dir="ltr">This case report and literature review examine the use of a relatively novel agent in a transfusion‐dependent beta‐thalassemia patient with extramedullary hematopoiesis (EMH). …"
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259
Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
منشور في 2021"…SEMA3A was not different at baseline; at hypoglycemia, SEMA3A decreased in controls only. Post-hypoglycemia, SEMA3A levels were higher in T2D versus controls. sNRP1 did not correlate with ACE2, REN or AGT. …"
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260
Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank
منشور في 2024"…<u>The Western Ontario and McMaster Universities Osteoarthritis Index</u> (WOMAC) is used to assess the severity of symptoms related to pain, stiffness, and function in diseased hip and knee joints. …"