A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... حسب Abou-Ghazal, Mohamed

"…Experimental Design: The antitumor activities and related mechanisms of WP1066 were investigated both in vitro on melanoma cell lines and in vivo on mice with subcutaneously syngeneic melanoma or with intracerebral melanoma tumors. …"
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Tumor protease-activated fusion toxins حسب Abi-Habib, Ralph J.

"…In this study, we demonstrate that DTU2GMCSF is highly potent against AML cell lines in vitro and is not toxic to normal cells both in vitro and in vivo. …"
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Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation حسب Shilpa Kuttikrishnan (3520079)

"…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"

Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 حسب Harshita Shailesh (14779408)

"…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …"

Inositol 1,4,5-Trisphosphate Receptors in Hypertension حسب Ali H. Eid (5461829)

"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca²⁺ signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP₃R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …"

Forecast of the outbreak of COVID-19 using artificial neural network: Case study Qatar, Spain, and Italy حسب Moayyad Shawaqfah (17280637)

"…The model sensitivity was analyzed using the root mean square error (RMSE), the mean absolute percentage error and the regression coefficient index R2, which yielded highly accurate values of the predicted correlation for the infected and dead cases of 0.99 for the dates considered. …"

Effect of 7-minute workout on weight and body composition حسب Mattar, L.

"…Waist circumference decreased between week 1 and 3 (P=0.003) and week 6 (P=0.01) by 4 cm on average. …"
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Ultrasound‑triggered herceptin liposomes for breast cancer therapy حسب Elamir, Amal

"…Exposing the liposomes to low-frequency ultrasound (LFUS) triggered drug release which increased with the increase in power density. Trastuzumab conjugation resulted in enhancing the sensitivity of the liposomes to LFUS. …"
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Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications حسب Tooba Yasin (19131382)

"…The biocompatibility of the composite hydrogels has been evaluated using fibroblast cell lines (<i>3T3</i>) after different time intervals (24–72 h), and it was found that increasing ZiF-8 caused the mature and spread cell morphology with increasing cell viability and proliferation under controlled in vitro conditions. …"

Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries حسب Mouyad Alsamara (17823668)

"…This study utilizes the nonlinear augmented mean group method to explore the possible asymmetric impact of remittance outflows on economic growth in Gulf Cooperation Council (GCC) countries for the period of 2000–2019. …"

Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries حسب Mouyad, Alsamara

"…This study utilizes the nonlinear augmented mean group method to explore the possible asymmetric impact of remittance outflows on economic growth in Gulf Cooperation Council (GCC) countries for the period of 2000–2019. …"
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The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis حسب Arwa Aldaalis (13355328)

"…Consequently, inactivation of SREBP1 in human liver and breast cancer cell lines reduces the expression of cyclin D1 and attenuates Rb phosphorylation. …"

Optimizing microgrid efficiency: Coordinating commercial and residential demand patterns with shared battery energy storage حسب Mohammadreza Gholami (17032317)

"…In response to the increasing integration of BESS in modern energy systems, this study investigates the implications of incorporating BESS within connected residential-commercial Microgrids (MGs). …"

Developing a Hybrid Model for Network Planning in Abu Dhabi Distribution Company Subsidiary of Adwea حسب Al Haddabi, Aseya Mohammed

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Effect of nickel loading on hydrogen production and chemical oxygen demand (COD) destruction from glucose oxidation and gasification in supercritical water حسب Youssef, Emhemmed A.

"…Results also showed that the presence of Ni increased the total gas yield increased in the 7.5–18 wt Ni/Al2O3 catalyst. …"
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Type 2 Diabetes Mellitus Automated Risk Detection Based on UAE National Health Survey Data: A Framework for the Construction and Optimization of Binary Classification Machine Learn... حسب Mohamed, AlShuweihi

"…This research motivated by the unprecedented increase in diabetes and specifically Type 2 Diabetes Miletus (T2DM), proposes two significant contributions. …"
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Alternative energy science and policy حسب Ammous, Saifedean H.

"…It is concluded that in situations where the cost and pollution functions of a fuel are unknown, subsidies, mandates and caps on the fuel might result in increased or decreased greenhouse gas emissions; on the other hand, a tax or cap on carbon dioxide results in the largest decrease possible of greenhouse gas emissions. …"
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Thermodynamic analysis of gravity assisted solar-powered reverse osmosis unit for greenhouses situated in a depleted zone حسب Yasser M. Abdullatif (14151324)

"…A solar-powered Rankine cycle is used to meet the energy demands of the RO and absorption cooling units. …"

Teachers’ Job Satisfaction in Instructional Delivery Modalities, and the Role of School Leaders: a Study among Selected Private Schools in Abu Dhabi. حسب YAHYA, AHMAD

"…It explores the best practices that school leaders can apply to meet the teachers’ job satisfaction. For example, the interviews recommended that school leaders are invited to build an active channel of communication with their teachers, share the decision-making process with them, decrease the workload, raise the teachers’ autonomy, and establish a remuneration system.…"
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