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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
منشور في 2020"…However, the mechanisms of anti-cancer effect of VCX either as a monotherapy or in combination with other chemotherapeutic agents against breast cancer need investigation.</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …"
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Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review
منشور في 2024"…Findings suggest that sexual risk behavior was taking place during the pandemic despite the lockdowns and highlight the need to minimize disruptions in provision of SHS during similar crises, particularly to key populations.…"
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Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms
منشور في 2024"…Such products need to be manufactured more often if companies want to survive in the Middle East as consumers will not settle for anything less. …"
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Blockchain, climate damage, and death: Policy interventions to reduce the carbon emissions, mortality, and net-zero implications of non-fungible tokens and Bitcoin
منشور في 2022"…With CO<sub>2</sub>-related deaths attributable to NFT transactions, social pressure from the art market has helped to progress the switch away from the deliberately polluting proof-of-work blockchains to more sustainable consensus protocols.</p><p dir="ltr">Nonetheless, many popular types of blockchain have resisted the pressure to decrease their environmental impact, including Bitcoin, whose attributed 2021 annual emissions will produce emissions responsible for around 19,000 future deaths. …"
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Salicylic acid restricts mercury translocation by activating strong antioxidant defense mechanisms in sweet pepper (Capsicum annum L.)
منشور في 2023"…., 0 μ M, 50 μ M, 100 μ M, and 150 μ M. The maximum decrease in photosynthetic machinery, plant growth attributes (shoot length, root length, no. of leaves, fresh and dry biomass (shoot and root)), and more accumulation of Hg in leaves, roots, and fruits of sweet pepper. …"
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New algorithm based active method to eliminate stick-slip vibrations in drill string systems
منشور في 2022"…This phenomenon can decrease the rate of penetration of drilling, wear of expensive equipment prematurely and cause catastrophic failures. …"
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Food purchase and eating behavior during the COVID-19 pandemic: A cross-sectional survey of Russian adults
منشور في 2021"…Indeed, the survey results suggested (i) a change in the modality of acquiring food, consumers reduced the number of shopping trips and buying more on each trip to minimize store visits; (ii) a surge of stockpiling of non-perishable food items; (iii) a shift toward healthier diets; (iv) an increase in culinary capabilities; (v) a decrease of food waste. …"
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Life cycle assessment of compressed air, vanadium redox flow battery, and molten salt systems for renewable energy storage
منشور في 2021"…In sensitivity analysis, it is found that using solar photovoltaic electricity for the considered energy storage methods rather than grid electricity critically reduces the associated environmental impacts, emphasizing the importance of implementing more renewables in the grid mix. The global warming potentials of compressed air and vanadium redox flow battery decrease by 0.599 and 0.420 kg CO<sub>2</sub> eq,/kWh, respectively in case photovoltaic electricity is stored instead of grid electricity. …"
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252
Colloid retention and mobilization mechanisms under different physicochemical conditions in porous media: A micromodel study
منشور في 2021"…Moreover, the removal efficiency by the moving gas-water interface was observed to be more for hydrophobic colloids compared to hydrophilic colloids for which the efficiency can be improved by lowering the ionic strength or increasing the pH value. …"
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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
منشور في 2025"…Further studies are needed to assess the impact of these novel therapies on end-organ-specific complications of SCD.…"
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Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study
منشور في 2022"…Participants had shown moderate resilience (mean score: 27.64 (SD = 8.31)) and their mean score fear of COVID19 was 15.67 (SD = 6.54). …"
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257
Which factor explains the life‐history of <i>Xanthium strumarium</i> L., an aggressive alien invasive plant species, along its altitudinal gradient?
منشور في 2022"…Among climatic variables, mean yearly temperature, mean annual yearly humidity, and mean day length in hours, while in soil variables, organic matter and nitrogen percentage significantly affect the phenological and morphological stages. …"
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258
Carotid artery revascularization through a radiated field
منشور في 2003"…All patients had received previous radiation therapy within a mean interval of 10 years (range, 1-26 years), with average radiation dose of 62 Gy (range, 50-70 Gy). …"
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259
Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial
منشور في 2023"…Beyond 2-year trial follow-up, Markov model predicted a decrease in colectomy rate, but it remained slightly higher for ciclosporin. …"
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
منشور في 2024"…These findings contribute to the growing understanding of nanoparticle toxicity profile and underscore the need for further research to ensure the safe application of nanoparticles in biomedical and other fields.…"