Exploring the LDHC Interactome as Novel Candidate Therapeutic Targets to Advance Breast Cancer Precision Medicine حسب Mariam Ahmed Amin Mohamed Elesnawy (21547187)

"…</p><p dir="ltr">Finally, silencing of <i>PKM2 </i>and<i> TUBA1B</i> in breast cancer cells increased DNA damage and decreased cancer cell survival, validating their role in genomic integrity and mimicking our previous observations following silencing of LDHC. …"

Properties and Microstructure Distribution of High-Performance Thermal Insulation Concrete حسب Malek Mohammad (17150977)

"…This material allows for better thermal insulation properties, thus decreasing the energy usage within the life cycle of the concrete structure. …"

Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression حسب Rayanah Barnawi (8737584)

"…Expression of FSCN1^high (identified in BRCA dataset from TCGA) in conjunction with elevated expression of the top 10 upregulated or decreased expression of the top 10 downregulated genes (identified in our FSCN1^CON vs. …"

SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs حسب Raed Shalaby (3756112)

"…Our results revealed that these selected chalcone analogs increased dopamine levels in the rat hepatoma (H4IIE) cells and decreased the relative mRNA expression of the MAO-B enzyme.…"

Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 حسب Razieh, Hassannejad

"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Providing Health Care in Armed Conflict Countries: The Case of Yemen حسب Esraa Ali Sayed Ali (20741327)

"…These challenges can be classified into two categories, first, administrative challenges related to difficulties faced by humanitarian organizations in introducing and delivering health services to the Yemeni Population Second, technical challenges related to health system constrains, this is due to the impact of the conflict on health</p><h3>Conclusion</h3><p dir="ltr">Since the complex, interlocking layer of conflict is not the only way to address the humanitarian crisis in Yemen, there are certain opportunities that focus on decreasing the effect of the war on the people of Yemen whilst still waiting for a political solution. …"

Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models حسب Ben Romdhane, Haifa

"…An extended dataset will enable a means to independently validate the defined models and test other modelling approaches. …"
احصل على النص الكامل

Effects of COVID-19 on Autism Spectrum Disorder in Qatar حسب Fouad A. Alshaban (17281108)

"…Parents also reported decreased access to family and social support networks, as well as decreased quality of clinical and community support. …"

Ratings of Perceived Exertion Misclassify Intensities for Sedentary Older Adults During Graded Cycling Test: Effect of Supramaximal High-Intensity Interval Training حسب Georges Jabbour (754884)

"…The relative intensity for both VT1 and VT2 were also objectively calculated based on the percent of maximal heart rate %HRmax and peak oxygen consumption %V˙O₂peak.…"

Prediction of critical total drawdown in sand production from gas wells: Machine learning approach حسب Fahd Saeed Alakbari (10701871)

"…The RSM correlation decreased the average absolute percent relative error (AAPRE) by 12.7% compared to all published correlations' AAPRE of 22.6%–30.4%. …"

Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study حسب Stefanos Volianitis (22155835)

"…Hepatic glucose output increased from 0.6 (0.5–0.7) to 1.5 (1.3–1.7) mmol/min, while arterial lactate increased from 0.8 (0.7–0.9) to 9.0 (8.1–9.9) mmol/L (<i>P</i> < 0.05) despite a rise in hepatic lactate uptake. …"

Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar حسب Doua Abdelrahman (17280667)

"…B19V DNA prevalence statistically decreased with age (p = 0.03). Anti-B19V IgG was detected in 60.3% (561/930) of the tested samples, while only 2.1% (20/930) were IgM-positive and 1.2% (11/930) were both IgM- and IgG-positive. …"

Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project حسب Mariam Al-Mutawa (18505317)

"…The Medical-Device Related Pressure Injuries (MDRPI) was reduced by 67.87%, from 0.46/1,000 patient-days [Q3 2020 – Q4 2021] to 0.15/1,000 patient-days [Q1 2022 – Q2 2023] (Figure2). …"

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S., El-Shoukrofy

"…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials حسب Yara Wanas (8744844)

"…The pooled estimates revealed that ARBs do not increase the risk of all-cause mortality (RR 1.00; 95%CI 0.97–1.04), myocardial infarction (RR 1.01; 95%CI 0.96–1.06), and stroke (RR 0.92; 95%CI 0.83–1.01). …"

Relationship between Asymmetry Indices, Anthropometric Parameters, and Physical Fitness in Obese and Non-Obese High School Students حسب Monoem Haddad (5345357)

"…In the second regression analysis, controlling for age, body mass, and BMI, the regression coefficients associated with height (B = −1.692, 95% CI [−3.115, −0.269], p < 0.05] and body fat percentage (B = 0.529, 95% CI [0.075, 0.983], p < 0.05) indicated that with each additional unit of height or body fat percentage, the CMJ AI decreased by 1.692 units and increased by 0.529 units. …"

The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort حسب Ken Van Alsenoy (14150559)

"…Braking force was decreased by 3.4±9.1% at LS and by 2.7±9.8% at HS for EVA compared to CON (P = 0.03, η² = 0.20). …"

Ozone and ozone/hydrogen peroxide treatment to remove gemfibrozil and ibuprofen from treated sewage effluent: Factors influencing bromate formation حسب Hajar Farzaneh (18526782)

"…Bromate formation was decreased to 0.012 mg/L when the pH was increased to 9. …"

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal حسب Zehra Irshad (18614869)

"…Silencing of HK-2 prevented increased glucose metabolism and MG formation. trans-Resveratrol and hesperetin combination (tRES-HESP) corrected increased MG and glucose metabolism by increasing expression of Glo1 and decreasing expression of HK-2. Increased MG glycation activates the UPR in endothelial cells and thereby may contribute to endothelial cell dysfunction in diabetic vascular disease where tRES-HESP may provide effective therapy.…"

Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish حسب Fatiha M. Benslimane (6695087)

"…In the last few decades, echocardiography has been applied to <i>in vivo</i> cardiac disease models, mainly to rodents. …"