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441
Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
منشور في 2024"…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …"
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442
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
منشور في 2020"…To characterize variability in lake extents, we analyzed summertime lake area loss (i.e., shrinkage) on two deltas over the past 20 years, using Landsat-derived water masks. …"
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443
Factors Associated with Meeting Current Recommendation for Physical Activity in Scottish Adults with Diabetes
منشور في 2019"…Furthermore, meeting the recommended physical activity levels decreased with age (OR 0.96; 95% CI 0.95–0.97), having a longstanding illness (OR 0.56; 95% CI 0.34–0.93) and body mass index (OR 0.94; 95% CI 0.92–0.97), but increased with higher fruit and vegetable intake (OR 1.16; 95% CI 1.07–1.25) and mental wellbeing (OR 1.04; 95% CI 1.02–1.06). …"
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444
Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression
منشور في 2021"…Expression of FSCN1<sup>high</sup> (identified in BRCA dataset from TCGA) in conjunction with elevated expression of the top 10 upregulated or decreased expression of the top 10 downregulated genes (identified in our FSCN1<sup>CON</sup> vs. …"
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445
Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient
منشور في 2023"…</p><h3>Hypothesis</h3><p dir="ltr">1) LRBA deficiency in the patient leads to decreased surface CTLA-4 expression level and therefore immune mediated type 1 diabetes mellitus. 2) LRBA protein may be involved in the insulin biosynthesis and secretion in β-cells.…"
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446
Persona Transparency: Analyzing the Impact of Explanations on Perceptions of Data-Driven Personas
منشور في 2019"…Contrary to our hypothesis, the perceived credibility of the personas decreases with the increased transparency, possibly due to the technical complexity of the persona profiles disrupting the facade of the personas being real people. …"
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447
The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery – A Follow-Up Study...
منشور في 2021"…LGS intervention significantly decreased CD4+ T-lymphocytes and effector memory (TEM) cells but increased T-regulatory (Treg), naïve, and central memory (TCM) cells, with all p values < 0.05. …"
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448
Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
منشور في 2023"…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …"
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449
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
منشور في 2022"…Two biochar application rates improved soil quality by increasing soil porosity from 49.3 to ≥ 53.4%, more than doubling cation exchange capacity to ≥ 21.1 cmolc.kg−1, providing a small reduction in bulk density of approximately 10% and decreasing electrical conductivity of the extract by at least 40% in comparison to control condition. …"
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450
The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature
منشور في 2021"…We additionally identified that short-term endurance training at moderate intensities and the combination of endurance, strength, balance, and flexibility training increase plasma IL-10 and reduce plasma IL-6 and TNF-α in healthy elderly adults and male patients with chronic heart failure. Strength training for 6-12 weeks did not alter plasma IL-1β, IL-2, IL-6 and TNF-α concentration in healthy elderly adults and patients with chronic-degenerative diseases, while 12 weeks of resistance training decreased muscle TNF-α mRNA in frail elderly individuals. …"
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451
Relationship between Asymmetry Indices, Anthropometric Parameters, and Physical Fitness in Obese and Non-Obese High School Students
منشور في 2022"…The purpose of this study was to investigate the relationship between age, anthropometric measurement, and asymmetry index (AI) in an adolescent high school population. Twenty-six male students (15 ± 1.0 years) were randomly selected. …"
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452
Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study
منشور في 2025"…Hemoglobin levels significantly increased from 6.4 to 11.1 g/dl (<i>p</i> < 0.001) after IV iron treatment, as did ferritin levels, while total iron-binding capacity decreased. …"
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453
Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
منشور في 2025"…A CSTR nutrient-recovery line on digested <i>Scenedesmus</i> recovered 68 % N and 72 % P via struvite, reducing synthetic fertilizer ∼35 %; flue-gas CO<sub>2</sub> (12 % v/v) lifted biomass 22 % and reduced carbon-supplement cost 86 %. …"
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454
Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats
منشور في 2023"…Consequently, this study sought out to explore the ameliorative effects of IL-35 and THYO against PAR-induced hepatotoxicity in rats. Sixty male rats were separated into six groups (10 rats/group): I control (0.5 mL NaCl, 0.9%/rat via oral gavage); II (IL-35), and III (TYHO) received intraperitoneal (i.p) injection of IL-35 (200 ng/kg) or THYO (0.5 mg/kg), respectively. …"
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455
The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort
منشور في 2019"…Braking force was decreased by 3.4±9.1% at LS and by 2.7±9.8% at HS for EVA compared to CON (P = 0.03, η<sup>2</sup> = 0.20). …"
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456
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
منشور في 2022"…The hypomorph mice are viable and fertile, with no overt defects.</li> <li>Decreased SOCE in the hypomorph mice is due to poor translocation of the mutant STIM1 to endoplasmic reticulum–plasma membrane contact sites resulting in fewer STIM1 puncta.…"
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457
Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models
منشور في 2020"…An extended dataset will enable a means to independently validate the defined models and test other modelling approaches. …"
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458
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459
Crystallization properties of arsenic doped GST alloys
منشور في 2019"…Optical band gap (E<sub>opt</sub>) values of the as-deposited films show a clear increasing trend; 0.6 eV for GST to 0.76 eV for (GST)<sub>0.85</sub>As<sub>0.15</sub>. The decreases in E<sub>opt</sub> for the samples annealed at higher temperatures shows significant optical contrast between the as-deposited and annealed samples. …"
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460
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
منشور في 2023"…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. …"