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661
Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism
Published 2024“…</p><h3>Results</h3><p dir="ltr">Patients within the PTH target range of 150 to 500pg/ml improved from 8% in June 2021 (on Cinacalcet) to 54% in June 2023 (on Etelcalcetide) (p=0 .0032) while patients with PTH above 1,000pg/ml decreased from 50% to 4% during the same period (p=0.00001) (Figure 2). …”
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662
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
Published 2024“…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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663
Geomorphological changes in the coastal area of Farasan Al-Kabir Island (Saudi Arabia) since mid Holocene based on a multi-proxy approach
Published 2018“…The mid Holocene evolution of the borehole area is resulted from the detailed analysis of five sedimentary units detected along the core Matar-1, and includes three distinct stages: (a) from 5253 ± 223 y cal BP to 3138 ± 223 y cal BP, carbonate coarse-grained material consisting of coral fragments, molluscs, calcareous algae and benthic foraminifera are deposited on a shallow marine fringing reefal platform, which becomes progressively a nearshore backreef (around 3675 ± 215 y cal BP), and later (around 3138 ± 223 y cal BP) a reef ramp; (b) since 3040 ± 220 y cal BP the borehole area obtains the characteristics of a high-energy beach that receives increasing inputs of terrigenous material; (c) subsequently, a supratidal backshore setting is established influenced mostly by terrestrial processes and occasionally by marine processes, as it is indicated by the decreasing and sometimes sporadic presence of benthic foraminifera, and recently, a sedimentary veneer consisting of terrigenous, carbonate and evaporite material is formed by terrestrial, mainly wadi and aeolian, processes. © 2018 Elsevier Ltd and INQUA…”
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664
Examining time-to-transport decisions in Emergency Medical Services
Published 2024“…</p><h3>Results</h3><p dir="ltr">Figure 1 indicates the transport probabilities as inferred from the Cox regression. …”
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665
Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts
Published 2020“…In an in-vitro cell model, these compounds decreased the insoluble phosphorylated α-syn and aggregation. …”
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666
Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health
Published 2019“…<p>Glycation, oxidation, nitration, and crosslinking of proteins are implicated in the pathogenic mechanisms of type 2 diabetes, cardiovascular disease, and chronic kidney disease. Related modified amino acids formed by proteolysis are excreted in urine. …”
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667
3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations
Published 2022“…<p dir="ltr">Despite the efforts devoted to drug discovery and development, the number of new drug approvals have been decreasing. Specifically, cardiovascular developments have been showing amongst the lowest levels of approvals. …”
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668
Enhancing the corrosion resistance of reinforcing steel under aggressive operational conditions using behentrimonium chloride
Published 2019“…Using only a 50 μmol L<sup>−1</sup> of BTC, we are able to measure an inhibition efficiency of 91, 79, and 71% in SCP solution with 3.5% NaCl at pH of 12.5, 10 and 7, respectively without showing any effect on the mechanical properties on the cured mortars. …”
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669
Efficient multi-objective neural architecture search framework via policy gradient algorithm
Published 2024“…Notably, compared with other multi-objective NAS methods, our NAS framework effectively decreases the computational burden (accounting for just 1/6 of the NSGA-Net). …”
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670
Performance and analysis of kappa-carrageenan hydrogel for PFOA-contaminated soil remediation wastewater treatment
Published 2024“…Finally, the kC-0.3%AC hydrogel removed 81.1% of PFOA from wastewater of 179 mg/L initial concentration compared to 79.3% for the kC-3%V hydrogel. …”
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671
Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients
Published 2022“…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …”
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672
Pilot scale evaluation of thin film composite membranes for reducing wastewater volumes: osmotic concentration process
Published 2023“…The membrane achieved a water flux of 10 LMH, which slightly decreased to 9.6 after 48 h of operation, mainly due to inorganic scaling. …”
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673
Vertical Distribution of Phosphorous Fractions and Bioavailability of the Nutrient in the Southern Indian Ocean
Published 2022“…The lower iron bound P fraction at specific depths was attributed to the nature of Fe minerals present within sediments. Decreased level of organic phosphate fraction was due to mineralization. …”
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674
Thermal challenges in lithium-ion battery technology: Investigating performance and thermal stability
Published 2025“…Results show a significant reduction in discharge capacity, decreasing from 38.12 mAh in the first cycle to 24.36 mAh after 350 cycles at 55 °C, corresponding to a 36.1 % capacity loss. …”
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Simultaneous adsorption-photocatalytic degradation of tetracycline by CdS/TiO<sub>2</sub> nanosheets/ graphene nanocomposites : Experimental study and modeling
Published 2021“…Cadmium sulfide (CdS) nanoparticles with various Cd/Ti molar ratios (0.35, 0.70, 1.40) were impregnated on the TNs/rGO(x) samples by the hydrothermal procedure. …”
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676
Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H<sub>2</sub>S: DFT study
Published 2021“…Moreover, the adsorption distance (D) between H<sub>2</sub>S and Cu/Zn-ZGNR decreased remarkably to 2.23 Å and an S–Cu bond was generated. …”
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677
Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data
Published 2023“…Within BMI categories, a similar increasing trend was observed in underweight, normal, and overweight patients, while from 2018 to 2020, there was a decreasing trend in rivaroxaban prescribing in all obese classes. …”
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Anabolic steroids-induced delirium
Published 2020“…Laboratory results showed a decreased plasma testosterone level of 9.59 nmol/l (10.4–37.4 nmol/l). …”
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680