Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy حسب Jia-Zhen Wu (6844793)

"…We also found increased levels of LAMP-1 and LAMP-2A both <i>in vitro</i> and <i>in vivo</i>, along with decreased levels of α-synuclein. …"

Chemical and microbiological investigations of metal ion interaction with norfloxacin حسب Na'was, T. E.

"…The ratios were NFX:AL3+, 2:1 and 3:1 for the NFX:Mg2+ complex. The formation of a complex with Al3+ enhanced the water solubility of the drug. …"
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Cost-benefit analysis of antimicrobial stewardship program in a cancer setting in Qatar حسب Dina Abushanab (10696501)

"…</p><h3>Results</h3><p dir="ltr">The benefit-to-cost ratio was 640, representing a benefit of 1,017 QAR generated for each 1 QAR invested in the ASP service. …"

ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder حسب Sara Cuvertino (18892069)

"…We also demonstrate that <i>ACTB</i> haploinsufficiency leads to reduced cell proliferation, altered expression of cell-cycle genes, and decreased amounts of nuclear, but not cytoplasmic, β-actin. …"

Treatment sequencing strategy for hepatic epithelioid haemangioendothelioma حسب Thomas, Ryan

"…However, 5-year survival for patients treated with chemotherapy at any point during their disease course was decreased compared with those who did not receive any chemotherapy (43.6% versus 82.9%, respectively; P = 0.02) and was predictive of a decreased overall survival on univariate analysis [HR 3.1 (CI 0.9–10.7), P = 0.02]. …"
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Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud... حسب Robert C Reiner (5147636)

"…Findings The greatest declines in diarrhoeal mortality were seen in south and southeast Asia and South America, where 54·0% (95% uncertainty interval [UI] 38·1–65·8), 17·4% (7·7–28·4), and 59·5% (34·2–86·9) of units, respectively, recorded decreases in deaths from diarrhoea greater than 10%. …"

Heat Transfer Coefficient Estimation of Falling Film for Horizontal Tube Multi-Effect Desalination Evaporator Using CFD حسب Furqan Tahir (14429547)

"…For a liquid load of Γ_1/2 = 0.09 kg/(m•s), the heat transfer coefficient at T_i = 85°C is 43.5 % higher as compared to that of at T_i = 5°C. …"

Genotypic and phenotypic characterization of Candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin حسب Toutounji, Maggie

"…Caspofungin sensitive strains showed decreased resistance to Congo red yet increased virulence and biofilm formation. …"
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Dividend policy and corporate investment under information shocks حسب Harakeh, Mostafa

"…Overall, I show how reducing information asymmetry mitigates agency conflicts over dividend policy and thereby decreases the probability of forgoing valuable investments to pay dividends, which is found to maximize shareholders’ wealth.…"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …"
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Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution حسب Kashif Bilal (16896357)

"…Moreover, user preferences and network’s contextual information can differentiate between live and cached access patterns optimizing edge caching decisions. …"

The Sources of Variance in the Helsinki Stock Exchange حسب Ben Sita, Bernard

"…Furthermore, inserting the ratio of volume expectation to duration expectation in the ARMA model and the vector error correction (VEC) model, we find that the short-term variance increases (decreases) when more (less) than 1 unit share is traded for 1 unit time.…"
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Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. حسب Daher, Costantine F.

"…In the chronic study, blood samples from fasted animals were subjectedto analyses after six months of either water [control] or water-juice [1:1] intake. Results: In the acutestudy, pineapple and grapefruit significantly decreased plasma triacylglycerol [TAG], and chylomicron[CM] TAG and cholesterol concentrations concomitantly with delayed gastric emptying. …"
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Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel حسب Ahmed Ben Ali (17792594)

"…In contrast, increasing the crosslinker content decreases the swelling ratio and increases the gel strength. …"

Potent anti-tumor promoting effects of Daucus carota oil extract in mice حسب Abou Zeinab, RM

"…Inraperitoneal treatment inhibited tumor yield by 43%, and decreased the tumor volume by 85% at week 20. Gavage treatment failed to inhibit the promotion of tumors but decreased tumor volume by 20%. …"
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Genotypic and phenotypic characterization of candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin. (c2018) حسب Toutounji, Maggie Nazih

"…Caspofungin sensitive strains showed decreased resistance to Congo red yet increased virulence and biofilm formation. …"
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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging حسب Dimassi, Hani

"…The children with white-matter abnormalities and decreased tone had significantly less signal intensity abnormality than the other study groups. …"
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study حسب Houssein H., Ayoub

"…Increasing symptomatic treatment coverage among FSWs from 0 % to 100 % decreases prevalence from 10.6 % to 4.5 %, 0.8 % to 0.4 %, and 0.3 % to 0.1 %, respectively. …"
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Effect of phosphorus supplementation on weight gain and waist circumference of overweight/obese adults حسب Bassil, MS

"…Similarly, BMI and waist circumference were significantly lower in the phosphorus group when compared with the placebo group (−0.24 kg m−2 (95% CI −0.59 to 0.12) vs 0.42 kg m−2 (95% CI 0.05 to 0.78), P=0.01; −3.62 cm (95% CI−4.90 to −2.33) vs 0.38 cm ( 95% CI−0.44 to 1.20), P<0.001; respectively). Several parameters of subjective appetite scores were decreased in the phosphorus-supplemented group. …"
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The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties حسب Jelena Eric (21015107)

"…</p><h3>Results</h3><p dir="ltr">Shade analysis revealed that, in the short term, HP treatment significantly increased lightness and Hue and decreased chroma compared to DW (<i>p </i>< 0.05); however, 1 week after treatment some of the initial gains in tooth lightness were partially lost. …"