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Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
Published 2024“…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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523
Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study
Published 2021“…<p dir="ltr">Density functional theory is used to study the adsorption of natural gas components in calcite (10.4) cylindrical nanopores with 1–4 nm diameters. The change of adsorption energy with the diameter of the nanopores is studied for CH<sub>4</sub> and CO<sub>2</sub> gases. …”
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524
Simulation of microscale particle interactions for optimization of an electrodynamic dust shield to clean desert dust from solar panels
Published 2017“…Dust transport distance per 10 cycles generally decreased as cycle frequency increased from 0.5 to 10Hz; however, transport distance per time was largest with an intermediate frequency of 1Hz. …”
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525
The Effects of Spirulina Supplementation on Cardiometabolic Risk Factors: A Narrative Review
Published 2024“…<p dir="ltr">Spirulina (<i>Arthrospira platensis</i>) is a cyanobacterium associated with multiple health benefits. …”
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526
Engineering the Surface and Mechanical Properties of Water Desalination Membranes Using Ultralong Carbon Nanotubes
Published 2018“…More pronounced effect on membrane’s mechanical properties was observed due to compatibility of CNTs with PS matrix when compared to other factors (i.e., changes in the CNT aspect ratio). The water contact angle for PS membranes incorporated with commercial CNT sharply decreased from 73° to 53° (membrane hydrophilization) for membranes with 0.1 and 1.0 wt. % of CNTs, while for the same loading of produced CNTs the water contact angles for the membrane samples increased from 66° to 72°. …”
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527
Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar
Published 2024“…Antimicrobials use and resource utilization, and their associated costs, declined after the maturity of ASP (i.e. positive cost saving), with a cost saving of QAR 458 (US$ 125) per 100-patient beds per year, signifying a benefit of QAR 458 generated for each QAR 1 invested in the ASP service. …”
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The cost associated with the development of the antimicrobial stewardship program in the adult general medicine setting in Qatar
Published 2024“…The operational costs decreased with the developed ASP. Whereas antimicrobial consumption and resource utilisation, and their associated costs, appear to have declined with the developed ASP, with a cost saving of QAR458 (US$125) per 100-patient beds, the avoided cost was negative, by QAR4,807 (US$1,317) per 100-patient beds, adding to a total QAR4,224 (US$1,160) increase in the 100-patient beds cost after ASP development.…”
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529
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
Published 2019“…Silencing of HK-2 prevented increased glucose metabolism and MG formation. trans-Resveratrol and hesperetin combination (tRES-HESP) corrected increased MG and glucose metabolism by increasing expression of Glo1 and decreasing expression of HK-2. Increased MG glycation activates the UPR in endothelial cells and thereby may contribute to endothelial cell dysfunction in diabetic vascular disease where tRES-HESP may provide effective therapy.…”
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530
Optoelectronic properties of highly porous silver oxide thin film
Published 2021“…</p><h2>Other Information</h2><p dir="ltr">Published in: SN Applied Sciences<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s42452-020-04091-1" target="_blank">https://dx.doi.org/10.1007/s42452-020-04091-1</a></p>…”
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Characterizing the Protein Coding RNAs (mRNA) and Long Non-Coding RNAs (LncRNAs) in Chemo Resistant Triple Negative Breast Cancer
Published 2023“…Our data highlighted cytokines and inflammatory response as the hallmark of doxorubicin resistance. Nonetheless, NEAT1 and MALAT1 lncRNAs were among the identified upregulated lncRNAs in response to doxorubicin treatment. …”
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532
Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials
Published 2020“…The pooled estimates revealed that ARBs do not increase the risk of all-cause mortality (RR 1.00; 95%CI 0.97–1.04), myocardial infarction (RR 1.01; 95%CI 0.96–1.06), and stroke (RR 0.92; 95%CI 0.83–1.01). …”
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CRISPR-Cas Controls Cryptic Prophages
Published 2022“…We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. Specifically, compared to the wild-type strain, reducing the amounts of specific interfering RNAs (crRNA) decreases growth by 40%, increases cell death by 700%, and prevents persister cell resuscitation. …”
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Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Published 2021“…B19V DNA prevalence statistically decreased with age (p = 0.03). Anti-B19V IgG was detected in 60.3% (561/930) of the tested samples, while only 2.1% (20/930) were IgM-positive and 1.2% (11/930) were both IgM- and IgG-positive. …”
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536
Global time differences in road traffic injuries among children and adolescents between and 1990 and 2013: Regional and economical perspectives from global burden of diseases study
Published 2015“…<p dir="ltr">In 2010, road traffic injuries (RTIs) are the leading cause of deaths in those aged 1-19 years globally and half of those victims are vulnerable road users (VRUs), defined as pedestrians, bicyclists and motorcyclists. …”
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537
The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort
Published 2019“…Braking force was decreased by 3.4±9.1% at LS and by 2.7±9.8% at HS for EVA compared to CON (P = 0.03, η<sup>2</sup> = 0.20). …”
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538
SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines
Published 2024“…We analyzed ADCC activity targeting SARS‐CoV‐2 spike (S) and nucleocapsid (N) proteins in convalescent sera following WT SARS‐CoV‐2‐infection (<i>n</i> = 91), including symptomatic and asymptomatic infections, omicron‐infection (<i>n</i> = 8), COVID‐19 vaccination with messenger RNA‐ (mRNA)‐ (BNT162b2 or mRNA‐1273, <i>n</i> = 77), adenovirus vector‐ (<i>n</i> = 41), and inactivated virus‐ (<i>n</i> = 46) based vaccines, as well as post‐mRNA vaccination BTI caused by omicron (<i>n</i> = 28). …”
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539
Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy
Published 2022“…This reduction was confirmed by FTIR analysis, as the phospholipid band (C=O) at 1740 cm−1 in Ex-4 treated cells is significantly decreased compared to steatotic cells. …”
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