From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease by Ahmad Raza (18205961)

“…Current vascular insults include the breakdown of the blood-brain barrier (BBB) and decreased brain perfusion, along with other contributory factors to conditions conducive to neurotoxicity. …”

Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study by Zlatan Zvizdic (9212371)

“…The median follow-up period was 42.6 months (IQR 12.5–71.2 months), revealing only one patient with testicular atrophy. The final testicular salvage rate was 35%.…”

Does Ultrasound Really Good Enough to Evaluate the Pneumothorax in the Emergency Department by Atilla Temel (17788481)

“…Thorax ultrasonography is a useful technique with high specificity in diagnosing pneumothorax, but its sensitivity decreases significantly when the size is below 1 cm.…”

Novel proteins implicated in lipid metabolism disorders by Nature Research (16552612)

“…Treating mice that have an <i>angptl3</i> gene mutation by introducing recombinant <i>angptl3</i> or by inducing overproduction of the protein has been found to elevate triglyceride and cholesterol levels.…”

Nutritional Status and Clinical Outcomes of Children with Medical Complexity in the United Arab Emirates: A Retrospective Cross-Sectional Study by Al Slaybe, Maryam

“…Results: Undernutrition was highly prevalent, with 60.8% of children classified as underweight, 49.1% as wasted, and 41.7% as stunted. According to the CIAF, 75.1% exhibited at least one form of anthropometric failure, while 54.9% presented with multiple concurrent forms. …”
Get full text
Get full text
Get full text

Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma by Abou-Ghazal, Mohamed

“…WP1066 achieved an IC50 of 1.6 μM, 2.3 μM, and 1.5 μM against the human melanoma cell line A375, murine melanoma cell line B16, and B16EGFRvIII, respectively. …”
Get full text
Get full text
Get full text

Enhanced thermoelectric properties of Bi₂Te_2.55Se_0.45 nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable... by Farah M. El-Makaty (14157090)

“…However, adding higher amounts (0.1, 0.5, and 1) decreased the electrical and thermal conductivities due to the dominant effect of bulky precipitates in increasing the scattering of charge carriers and phonons. …”

An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH₄-CO₂-H₂S by Hani Ababneh (9218272)

“…However, acid gases have to be removed before the natural gas produced from these fields could be used. One of the novel concepts in this field is the utilization of solid phase formation of carbon dioxide and/or hydrogen sulfide. …”

Past and future climate effects on population structure and diversity of North Pacific surfgrasses by Ana I. Tavares (6942986)

“…</p><h3>Results</h3><p dir="ltr">SDMs revealed southward range shifts during the LGM and potential poleward expansions in the future. Genetic diversity of <i>Phyllospadix torreyi </i>decreases from north to south, but in <i>Phyllospadix scouleri</i> the trend is variable. …”

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity by Mohamed Abu-Farha (18535590)

“…In obese, the proteomic profiling before and after 3 months of physical exercise showed differential expression of 38 proteins. Thrombospondin 1 (TSP1) was among the proteins that were upregulated in obese subjects and then decreased by physical exercise. …”

Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care by Ahmad Kloub (16855149)

“…VTE incidence after protocol implementation decreased from 4 to 1.3% (OR 0.31; 95% CI 0.1–0.9, P = 0.03) without increasing the bleeding rate. …”

Direct Oral Anticoagulants Compared to Warfarin in Patients with Intermediate‐ to High‐Risk Pulmonary Embolism: A Systematic Review and Meta‐Analysis by Mohamed Nabil Elshafei (9960500)

“…There was no significant difference in the safety outcomes (major and minor bleeding events), with a trend towards a decreased risk among direct oral anticoagulant treated cohorts (OR 0.3, 95% CI 0.08–1.1) and (OR 0.64, 95% CI 0.24–1.7), respectively.…”

Occurrence and removal characteristics of phthalate esters from bottled drinking water using silver modified roasted date pits by Fedae A. Alhaddad (14152161)

“…</p> <h2>Results</h2> <p>The results indicated that the most abundant phthalate esters were DMP followed by DEP under 30 °C; however, DNOP was not detected in any of the tested water samples, except for one sample under 30 °C with a concentration of 0.031 μg/mL. …”

Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study by Ayman Al-Dahshan (8962568)

“…The multivariate analysis identified having hypertension (AOR 1.71; 95% CI: 1.38–2.13), diabetes (AOR 2.38; 95% CI: 1.97–2.87), dyslipidemia (AOR 1.29; 95% CI: 1.06–1.56), cardiovascular disease (AOR 1.56; 95% CI: 1.25–1.95) and asthma (AOR 1.39; 95% CI: 1.13–1.72) to be independent parameters associated with polypharmacy. …”

Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study by Ayman Al-Dahshan (8962568)

“…The multivariate analysis identified having hypertension (AOR 1.71; 95% CI: 1.38–2.13), diabetes (AOR 2.38; 95% CI: 1.97–2.87), dyslipidemia (AOR 1.29; 95% CI: 1.06–1.56), cardiovascular disease (AOR 1.56; 95% CI: 1.25–1.95) and asthma (AOR 1.39; 95% CI: 1.13–1.72) to be independent parameters associated with polypharmacy. …”

دور مكاتب الإصلاح والوساطة والتوفيق الأسري في الأردن في الحد من النزاعات الأسرية من وجهة نظر العاملين بها... by Al-Oqaili , Amneh Irshied

Get full text

Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans by Kevin S. Chen (9201767)

“…Three of these compounds also decreased α-synuclein oligomers in mammalian neurons, including rifabutin which has not been previously investigated for Parkinson’s disease. …”

Exergames versus self-regulated exercises with instruction leaflets to improve adherence during geriatric rehabilitation: a randomized controlled trial by Peter Oesch (3572426)

“…Adherence was comparable at day one (38 min. in the EG and 42 min. in the CG) and significantly higher in the CG at day 10 (54 min. in the CG while decreasing to 28 min. in the EG, <i>p</i> = 0.007, ES 0.94, 0.39–0.151). …”

The role of IT governance in enhancing the competitiveness of for-profit private schools' business by Jasim, Alaa H

Get full text

Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases by Glazer, Evan

“…Chemotherapy changes the activity of a malignant lesion,1,10,11 but exactly how much is unclear. There appears to be a correlation between decreasing PET uptake and reduction in tumor burden; however, hypometabolic lesions may still harbor viable malignant cells.10,11 In addition, the authors reviewed the temporal relationship between chemotherapy and false-negative and false-positive results on PET. …”
Get full text
Get full text
Get full text