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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound <b>2a</b>. …”
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Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy
Published 2022“…<div><p>Non-alcoholic fatty liver disease (NAFLD) is a common liver lesion that is untreatable with medications. …”
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Dynamic Stability Analysis in Hybrid Nanocomposite Polymer Beams Reinforced by Carbon Fibers and Carbon Nanotubes
Published 2020“…To model the structure realistically, exponential shear deformation beam theory (ESDBT) is applied and using energy methods, governing equations are achieved. …”
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Multi-Objective Optimisation of Injection Moulding Process for Dashboard Using Genetic Algorithm and Type-2 Fuzzy Neural Network
Published 2024“…Its purpose was to estimate shear and residual stress levels. Additionally, the multi-objective genetic algorithm (MOGA) was utilised to extract the most optimal parameters for the injection moulding process, aiming to minimise shear and residual stress and thereby increase the resistance of the final product. …”
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Fanconi–Bickel Syndrome: A Review of the Mechanisms That Lead to Dysglycaemia
Published 2020“…<p dir="ltr">Accumulation of glycogen in the kidney and liver is the main feature of Fanconi–Bickel Syndrome (FBS), a rare disorder of carbohydrate metabolism inherited in an autosomal recessive manner due to SLC2A2 gene mutations. …”
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Numerical Evaluation of Pre-Damaged Beam Using Recycled Concrete Aggregate Strengthened by FRP Sheets
Published 2022“…The purpose of having this kind of research is trying to predict the effect of strengthening RCA reinforced beam samples with CFRP without shear reinforcement on deflection and damage mode types (Shear- Moment). …”
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Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia
Published 2006“…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …”
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Effect of Crude Oil Products on the Geotechnical Properties of Sandy Soil
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Hepatoprotective, Antioxidant, and Anticancer Effects of the Tragopogon porrifolius Methanolic Extract
Published 2015“…Additionally, the extract caused a dose-dependent decrease in cell viability and proliferation. In conclusion, the methanolic extract of T. porrifolius displayed a relatively high antioxidant activity both in vitro and in vivo as well as hepatoprotective potential against liver toxicity in rats and anticancer effect on MDA-MB-231 and Caco-2 cells.…”
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Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions
Published 2017“…The results of a very systematic study are presented regarding rheological measurements of 7% mass concentration at different temperatures, ranging between 25 and 80 °C at atmospheric pressure. Higher temperature increased the shear stresses at low shear rates while the effect was much smaller at higher shear rates. …”
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Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
Published 2010“…The decrease in transfusion rate associated with the use of the 2-surgeon technique emphasizes the important role of the hepatobiliary surgeon in determining outcomes after liver resection. …”
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Strain response of hot-mix asphalt overlays for bottom-up reflective cracking
Published 2017“…Results obtained show that the rate of horizontal and shear strain increase at the bottom of the HMA overlay drop with higher vehicle speed, higher subgrade modulus, and higher subbase modulus. …”
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1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH
Published 2010“…In the Phase I study, mean IPSS showed a decrease of 6.5 points (34%), mean QoL a decrease of 2 points (44%) and mean prostate volume a decrease of 5.5 cc (13%) at 12-months compared to screening. …”
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Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats
Published 2015“…No hydroxycut-related changes in serum activities of serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate dehydrogenase (SGPT), lactate dehydrogenase (LDH), and creatinine phosphokinase (CPK) enzymes were noted, indicating no liver damage occurred. A decrease in liver fat content was observed with hydroxycut intake. …”
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Experimental Investigation of the Near Wake of a Pick-up Truck
Published 2003“…The cab shear layer evolves more slowly than the underbody flow shear layer and does not interact strongly with the tailgate for the present geometry. …”
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