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281
Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
Published 2023“…The present pilot study represents a novel dietary means by which to reduce BCAA, and as such, provides a blueprint for a potential dietary therapeutic in obesity/diabetes.…”
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282
Fanconi–Bickel Syndrome: A Review of the Mechanisms That Lead to Dysglycaemia
Published 2020“…Missense, nonsense, frame-shift (fs), in-frame indels, splice site, and compound heterozygous variants have all been identified in SLC2A2 gene of FBS cases. Approximately 144 FBS cases with 70 different SLC2A2 gene variants have been reported so far. …”
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283
Cost-benefit analysis of antimicrobial stewardship program in a cancer setting in Qatar
Published 2024“…<h3>Background</h3><p dir="ltr">It is estimated that physicians prescribe antibiotics inappropriately in 50% of cases.1,2 We aimed to compare the economic advantage of mature antimicrobial stewardship program (ASP) versus premature ASP use in hematology and oncology settings in Qatar. …”
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284
Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study
Published 2021“…The nanopores absorbed up to 28 and 24 molecules of CH<sub>4</sub> and CO<sub>2,</sub> respectively, and the adsorption energy decreased to −0.0062 and −0.0075 eV/Å<sup>2</sup> for each. …”
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285
Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2021“…During the same period, age-standardised rates of stroke incidence decreased by 17·0% (15·0–18·0), mortality decreased by 36·0% (31·0–42·0), prevalence decreased by 6·0% (5·0–7·0), and DALYs decreased by 36·0% (31·0–42·0). …”
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286
Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model
Published 2022“…Moreover, the cutaneous wound tissues treated with PDL 20, MM, and QM exhibited significantly higher hydroxyproline content than the negative control group, which means a high collagen biosynthesis in wound tissues. …”
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287
A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
Published 2022“…The results indicate that there are only a few cases of inadequate hole cleaning that drill-pipe rotation cannot control, and those cases are associated with the operation in vertical wellbore sections. …”
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288
Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure
Published 2015“…<p dir="ltr">For the last fourteen years in Japan, casualties due to traffic collisions have decreased. There were 9,073 traffic fatalities in 2000 and 4,113 in 2014. …”
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289
Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application
Published 2023“…Patient satisfaction from the provided interventions/services was determined by means of an overall rating. The correlation between practiced roles and patient satisfaction with received interventions/services was determined.…”
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290
Frugal innovation for sustainable rural development
Published 2023“…Using a grounded theory method and based on 22 interviews with key informants related to 13 cases of frugal enterprise in South Asia, this qualitative study attempts to accomplish the aim of the study. …”
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291
Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss
Published 2018“…Moreover, our preliminary data suggest that a relevant proportion of ARHL cases could be explained by SLC7A8 mutations.</p><h2>Other Information</h2><p dir="ltr">Published in: eLife<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.7554/elife.31511" target="_blank">https://dx.doi.org/10.7554/elife.31511</a></p>…”
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292
Non-Isolated DC–DC Power Converter With High Gain and Inverting Capability
Published 2021“…The parasitic of the components has been considered in the analysis to show the deviation from the ideal cases. A detailed comparison with the other available converters is presented. …”
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293
Driving and hypoglycemia
Published 2015“…Three hundred and eighty seven million people have diabetes worldwide and more than 37 million people in the MENA Region; by 2035 this will rise to 68 million. There were 303,700 cases of diabetes in Qatar in 2014. Large number of diabetic patients will seek or currently hold a license to drive. …”
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294
Understanding the Molecular Mechanisms of Dysglycemia in Patients with Fanconi-Bickel Syndrome
Published 2023“…In this study, we report three new cases of FBS with classical phenotypes of FBS associated with dysglycemia. …”
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295
Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity
Published 2020“…The purified scFvs showed specific activity towards α-syn fibrils and oligomers in comparison to monomers and recognized intracellular inclusions in human post-mortem brain tissue of Lewy body disease cases, but not aged controls. In vitro studies indicated scFvs inhibit the seeding of α-syn aggregation in a time-dependent manner, decreased α-syn seed-induced toxicity in a cell model of PD, and reduced the production of insoluble α-syn phosphorylated at Ser-129 (pS129-α-syn). …”
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296
Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31
Published 2020“…Using another affected member, DGDP289B, with a microdeletion at Xp22.31, in this family, we performed the genomic and clinical delineation with six published and nine unreported cases. We propose HDHD1 and PNPLA4 for X-linked intellectual disability in this region, since their high transcript levels in the human brain substantiate their role in intellectual functioning.…”
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297
Ozone and ozone/hydrogen peroxide treatment to remove gemfibrozil and ibuprofen from treated sewage effluent: Factors influencing bromate formation
Published 2020“…Bromate formation was decreased to 0.012 mg/L when the pH was increased to 9. …”
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298
Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient
Published 2023“…To our knowledge, all reported cases of diabetic patients with LRBA mutation were compiled in this research. …”
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299
Automatic image quality evaluation in digital radiography using for‐processing and for‐presentation images
Published 2024“…The expected positive effect that increasing IAK and decreasing tube potential should have on IQ was clearly exhibited in two IQ metrics only, the signal difference‐to‐noise‐ratio (SDNR) and the detectability index (d’), for both image types. …”
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300
Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
Published 2019“…</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">CPHN cell frequency decreased 84% (islets) and 42% (clusters) from fetal to infant life. …”
