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321
Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
Published 2018“…Increased glucose entry into glycolysis in fibroblast senescence is mainly mediated by increased hexokinase-2. SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …”
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322
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
Published 2020“…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…”
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323
Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
Published 2022“…During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). …”
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324
Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload
Published 2024“…Incretin effect impairment is characterized by decreased secretion of incretins from enteroendocrine cells and incretin resistance of pancreatic β-cells. …”
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325
LDL-C Targets in Secondary Prevention: How Low Should We Go?
Published 2019“…<h3>Abstract</h3><p dir="ltr">The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. …”
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326
Preterm birth in low-middle income Countries
Published 2024“…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …”
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327
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
Published 2022“…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …”
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328
The influence of different preparation methods on the erosion behavior of NiP-ZrO<sub>2</sub> nanocomposite coating
Published 2023“…The erosion mechanism is mainly fracturing of splats and ploughing action at low particle velocity due to the ductility merits of the different coatings. …”
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329
The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery – A Follow-Up Study...
Published 2021“…</p><h3>Results </h3><p dir="ltr">The means (SD) of age and BMI of class III obesity subjects was 32.32 (8.36) years and 49.02 (6.28) kg/m<sup>2</sup>, respectively. …”
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330
Characterizing the Protein Coding RNAs (mRNA) and Long Non-Coding RNAs (LncRNAs) in Chemo Resistant Triple Negative Breast Cancer
Published 2023“…While the five-year survival rate of cases diagnosed with early-stage localized BC is about 99%, this number drastically drop for advanced and metastatic cases. …”
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Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
Published 2023“…The present pilot study represents a novel dietary means by which to reduce BCAA, and as such, provides a blueprint for a potential dietary therapeutic in obesity/diabetes.…”
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333
The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms
Published 2025“…The gut microbiota, comprising mainly firmicutes and bacteroidetes, play a key role in CRC development and prevention. …”
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334
Cost-benefit analysis of antimicrobial stewardship program in a cancer setting in Qatar
Published 2024“…<h3>Background</h3><p dir="ltr">It is estimated that physicians prescribe antibiotics inappropriately in 50% of cases.1,2 We aimed to compare the economic advantage of mature antimicrobial stewardship program (ASP) versus premature ASP use in hematology and oncology settings in Qatar. …”
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335
Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study
Published 2021“…The nanopores absorbed up to 28 and 24 molecules of CH<sub>4</sub> and CO<sub>2,</sub> respectively, and the adsorption energy decreased to −0.0062 and −0.0075 eV/Å<sup>2</sup> for each. …”
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336
Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2021“…During the same period, age-standardised rates of stroke incidence decreased by 17·0% (15·0–18·0), mortality decreased by 36·0% (31·0–42·0), prevalence decreased by 6·0% (5·0–7·0), and DALYs decreased by 36·0% (31·0–42·0). …”
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337
Geomorphological changes in the coastal area of Farasan Al-Kabir Island (Saudi Arabia) since mid Holocene based on a multi-proxy approach
Published 2018“…The mid Holocene evolution of the borehole area is resulted from the detailed analysis of five sedimentary units detected along the core Matar-1, and includes three distinct stages: (a) from 5253 ± 223 y cal BP to 3138 ± 223 y cal BP, carbonate coarse-grained material consisting of coral fragments, molluscs, calcareous algae and benthic foraminifera are deposited on a shallow marine fringing reefal platform, which becomes progressively a nearshore backreef (around 3675 ± 215 y cal BP), and later (around 3138 ± 223 y cal BP) a reef ramp; (b) since 3040 ± 220 y cal BP the borehole area obtains the characteristics of a high-energy beach that receives increasing inputs of terrigenous material; (c) subsequently, a supratidal backshore setting is established influenced mostly by terrestrial processes and occasionally by marine processes, as it is indicated by the decreasing and sometimes sporadic presence of benthic foraminifera, and recently, a sedimentary veneer consisting of terrigenous, carbonate and evaporite material is formed by terrestrial, mainly wadi and aeolian, processes. © 2018 Elsevier Ltd and INQUA…”
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338
Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model
Published 2022“…Moreover, the cutaneous wound tissues treated with PDL 20, MM, and QM exhibited significantly higher hydroxyproline content than the negative control group, which means a high collagen biosynthesis in wound tissues. …”
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339
A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
Published 2022“…The results indicate that there are only a few cases of inadequate hole cleaning that drill-pipe rotation cannot control, and those cases are associated with the operation in vertical wellbore sections. …”
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Pilot scale evaluation of thin film composite membranes for reducing wastewater volumes: osmotic concentration process
Published 2023“…The membrane achieved a water flux of 10 LMH, which slightly decreased to 9.6 after 48 h of operation, mainly due to inorganic scaling. …”