Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"

Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery حسب Stephen L. Atkin (6684368)

"…</p><p dir="ltr"><br></p><h3>Methods: </h3><p dir="ltr">Twenty-nine type 2 patients with severe obesity (mean BMI 46.2 kg/m²) and diabetes underwent Roux-en-Y gastric bypass (RYGB) surgery. …"

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... حسب Michael, Brauer

"…From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …"
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Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th... حسب Jaimie D Steinmetz (18015919)

"…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global crude prevalence of avoidable vision impairment and blindness in adults aged 50 years and older did not change between 2010 and 2019 (percentage change −0·2% [95% UI −1·5 to 1·0]; 2019 prevalence 9·58 cases per 1000 people [95% IU 8·51 to 10·8], 2010 prevalence 96·0 cases per 1000 people [86·0 to 107·0]). …"

Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort حسب Fatima Qafoud (14778571)

"…Elevated QTc was observed in CAD patients, whereas decreased QTc was correlated with decreased levels of calcium and potassium. …"

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Brittney S Sheena (9715568)

"…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …"

Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish حسب Fatiha M. Benslimane (6695087)

"…<p dir="ltr">Ultrasonography is the most widely used imaging technique in cardiovascular medicine. …"

Machine Learning-Based Management of Electric Vehicles Charging: Towards Highly-Dispersed Fast Chargers حسب Mostafa Shibl (18810412)

"…The substantial power used through charging EVs has undeniable negative impacts on the power grid. …"

Flavonoids Alleviate Peripheral Neuropathy Induced by Anticancer Drugs حسب Manaal Siddiqui (18891637)

"…Methods: PubMed and Google Scholar were used, and studies that investigated flavonoids in models of CIPN and models of neuropathic pain similar to CIPN were included. …"

Effects of visual field impairment on driving حسب Jan Andersson (218600)

"…An advanced driving simulator was used to develop a simulated driving task, which also included a choice reaction test performed while driving on a rural road. …"

Technical assessment of different extraction methods and transcriptome profiling of RNA isolated from small volumes of blood حسب Mahesh Kumar Reddy Kalikiri (17886695)

"…<p dir="ltr">Transcriptome profiling of human whole blood is used to discover biomarkers of diseases and to assess phenotypic traits. …"

Therapeutic targeting of the TPX2/TTK network in colorectal cancer حسب Hibah Shaath (5599658)

"…</p><h3>Methods</h3><p dir="ltr">RNA-Seq was conducted using the illumina platform, while bioinformatics analyses were conducted using CLC genomics workbench and iDEP.951. …"

Reduced graphene aerogels as energy efficient selective oil sorbents حسب Junaid Saleem (14670322)

"…<p dir="ltr">Graphene aerogels are widely used in the oil–water system as they possess high internal surface area and super-oleophilic properties. …"

Aorta deformation linked to heart disease حسب Nature Research (16552612)

"…<p>A cardiovascular condition called hypertrophic cardiomyopathy is associated with abnormal mechanical properties of the aorta, which could be used in the clinic to assess risk for the disease, according to new research published in the journal Global Cardiology and Practice . …"

An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH₄-CO₂-H₂S حسب Hani Ababneh (9218272)

"…A model based on equilibrium stage separation unit was used to study the separation of three different feed compositions of this ternary system. …"

Topical Vancomycin for Prevention of Surgical Site Infection after Craniotomy: Meta-analysis and Systematic Literature Review حسب Ahmed Saleh (3150639)

"…</p><h3>Conclusions</h3><p dir="ltr">The results of this meta-analysis suggest that the use of topical vancomycin after performing craniotomies is safe and effective in decreasing the incidence of cSSIs, although there is a need to perform randomized controlled trials to strongly support this conclusion.…"

Postmicturition dribble in men with no previous urogenital surgery: Systematic review and meta‐analysis of treatment modalities حسب Ahmed Albakr (14058051)

"…Study quality and risk of bias were evaluated using established tools. We extracted a range of variables including treatment modality used and its effectiveness on PMD volume and patient complaint. …"

Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank حسب Al-Hamdani, Mohammed

"…The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is used to assess the severity of symptoms related to pain, stiffness, and function in diseased hip and knee joints. …"
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Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model حسب Wiem Elloumi (17148337)

"…Results showed that the topical application of PDL (at a concentration of 20 mg/ml) (PDL 20), MM, and QM increased wound healing and decreased inflammatory cells infiltration compared to the negative control group. …"

Tranexamic Acid Application in Facial Aesthetic Surgery: An Umbrella Review حسب Mohamed Badie Ahmed (10223510)

"…While in the case of septorhinoplasty, 3 studies revealed that TXA use decreased BLV. Moreover, in the case of rhytidectomy, 3 out of 6 systematic reviews showed reduction in BLV, while 2 reported reductions in DOS. …"