Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 by Ramada R. Khaswaneh (22224544)

“…Severe hypoxia found to decrease the survival chances of MSCs after transplantation; however, little is known about the impact of severe hypoxia on modulating the complement system activity and its effect on MSCs survival. …”

Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up by Wahiba Elhag (5245547)

“…The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). …”

Impact of severe hypoglycemia on the heat shock and related protein response by Alexander S. Atkin (18520107)

“…In the post-hypoglycemia follow-up period, most proteins normalized to baseline by 24-h; however, STIP1 (p = 0.003), UBE2N (p = 0.004) and UBE2L3 (p < 0.04) were decreased in controls at 24-h. …”

Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort by Mohamed Adil Shah Khoodoruth (14589828)

“…Multivariate analysis highlighted significant differences in platelet count, mean platelet volume (MPV), TG, HbA1c, BMI, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and ferritin among the groups. …”

Football-induced fatigue in hypoxia impairs repeated sprint ability and perceptual-cognitive skills by Samuel A. Pullinger (8154627)

“…Simulated matches in hypoxia revealed larger decreases, in RS and perceptual-cognitive skills, highlighting the need for optimal acclimatisation strategies, including physical and technical preparation, prior to playing at altitude.…”

Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer by Adviti Naik (673163)

“…Following <i>LDHC</i> knockdown, we observed an increase in the secretion of tumor-derived pro-inflammatory cytokines (IFN-γ, GM-CSF, MCP-1, CXCL1), a decrease in the soluble levels of tumor-derived immunosuppressive factors (IL-6, Gal-9) and reduced tumor cell surface PD-L1 expression. …”

Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample by Menatalla Mekhaimar (14103708)

“…In patients with HF and DM, mean (SD) age slightly decreased from 71 (13) to 70 (13) years, in which 47.5% were males in 2005 as compared with 52% in 2014 (p trend < 0.001 for both). …”

Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills by Abbas, Tariq

“…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …”
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications by Amr Nasr Fekry (22521185)

“…Comprehensive isotherm analysis revealed the Dubinin-Radushkevich model provided the best fit (R² = 0.998), indicating physical adsorption as the predominant mechanism, as the calculated mean free energy (E = 5.00 kJ/mol) falls within the 1–8 kJ/mol range characteristic of physical adsorption. …”

Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels by Haya Al-Sulaiti (5449256)

“…Rats (n = 14) were divided into three groups: control (<i>n</i>= 2), AuNPs (<i>n</i>= 6) and AgNPs (<i>n</i>= 6), to mimic potential biomedical exposure scenarios. …”

Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis by Maria K. Smatti (4675852)

“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations.…”

Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery by Stephen L. Atkin (6684368)

“…</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">BMI decreased by 3.8 kg/m² 21 days postoperatively. …”

The Effect of Olanzapine, Tart Cherry, Fish Oil and High Fat in the Composition of the Gut Microbiome in Obese Mice by Amal Awadalla Mohamed Ali (20433692)

“…In comparing between LF and HF diet, <i>Faecalibaculum</i> was high in LF, whereas <i>Mucispirillum, Ruminiclostridium, </i>and<i> Roseburia</i> increased in HF diet.…”

Long-Haul Northeast Travel Disrupts Sleep and Induces Perceived Fatigue in Endurance Athletes by Christopher J. Stevens (3391547)

“…After this time, sleep duration returned to baseline for several days until it was very likely decreased on the night prior to competition (-1.2 ± 1.0 h; 1.18; ±0.93). …”

The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar by Komal Rafique (17075074)

“…In women who were taking metformin, those having risk factors had lower mean BW (3015± 608.1 gms vs 3179.2± 506.2 grams; p<0.001), higher risk of PTD (20% vs 10.2%; p<0.001), LBW (16.5% vs 7.2%. p<0.001), SFD (8.0% vs 3.6%; p=0.006), and admission to NICU (19.5% vs 11.3%; p<0.001) and cesarean (48.0% vs 36.8%; p<0.001) compared to those who without risk factors. …”

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 by Hedyeh Ebrahimi (7321358)

“…From 2010 to 2019, the number of new tracheal, bronchus, and lung cancer cases increased by 23·3% (12·9 to 33·6) globally and the number of larynx cancer cases increased by 24·7% (16·0 to 34·1) globally. Global age-standardised incidence rates of tracheal, bronchus, and lung cancer decreased by 7·4% (−16·8 to 1·6) and age-standardised incidence rates of larynx cancer decreased by 3·0% (−10·5 to 5·0) in males over the past decade; however, during the same period, age-standardised incidence rates in females increased by 0·9% (−8·2 to 10·2) for tracheal, bronchus, and lung cancer and decreased by 0·5% (−8·4 to 8·1) for larynx cancer. …”

Clotted blood samples in the neonatal intensive care unit: A retrospective, observational study to evaluate interventions to reduce blood sample clotting by Matheus F. P. T. van Rens (17993767)

“…The overall rate of clotted specimens decreased from 4.8% in 2017 and 2018 to 2.4% in 2019, with odds ratios of 1.42 (95% confidence interval [CI] 1.13–1.78, p = .002), 1.46 (95% CI 1.17–1.81, p < .001) and 0.49 (95% CI 0.39–0.63, p < .001), respectively. …”

High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis by Nabil Shallik (15900256)

“…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …”

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019 by Christopher J L Murray (18278781)

“…</p><h3>Findings</h3><p dir="ltr">Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). …”

A Multidecadal Assessment of Haze Development and Fluctuations in Visibility for Arabian Peninsula by Luqman Atique (16036586)

“…Visibility in KWT was 0.5 km in 1994, indicating a period of exceptionally poor visibility whereas the daily mean visibility for KSA was approximately 0.6 km. …”