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121
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …”
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122
Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS
Published 2018“…Skewed data were log transformed and expressed as mean ± SEM.</p><h3>Results</h3><p dir="ltr">Before exercise, women with PCOS had a higher HOMA-IR and lower VO2 max than controls. …”
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123
Wasted Da’am: Evaluating the Impact of Food Waste Management Practices on the Environment in Hotels in Qatar
Published 2025“…Interestingly, the result showed that for every decrease in the number of guests, methane decreased by 0.009 kilograms, and the absence of technological efficiency increased methane by 3.30kg. …”
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124
Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts
Published 2022“…The mean Hibbs angle decreased from 153.07 to 142.32° (MD = 10.54°, p < 0.001). …”
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125
The Economic Impact of Optimizing a COVID-19 Management Protocol in Pre-Existing Cardiovascular Disease Patients
Published 2023“…In the critically ill patients, however, the cost increased from QAR202,094 (USD 55,505) to QAR292,856 (USD 80,433) per patient, with added cost of QAR90,762 (USD 24,928). …”
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126
An Improved Genghis Khan Optimizer based on Enhanced Solution Quality Strategy for Global Optimization and Feature Selection Problems
Published 2024“…In order to address this issue in GKSO, a more refined version called I-GKSO is implemented. …”
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127
A potential therapeutic agent for sickle cell anaemia
Published 2016“…Oxidative stress is an imbalance that results when more ROS are produced than the body’s antioxidant defences can handle. …”
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128
Qatar’s immigrants at higher risk of diabetes
Published 2015“…Of the South Asian and Filipino participants, 38% had glycated haemoglobin levels of more than 6%, which is indicative of impaired glucose metabolism or undiagnosed T2D. …”
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129
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Published 2023“…Age-standardised prevalence, YLDs, and underlying causes of HF were compared by 5-year age groups (considering 15 years old and more), sex (male and female), and countries. FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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130
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
Published 2024“…FindingsIn 2021, the global age-standardised mortality rate of appendicitis was 0·358 (95% uncertainty interval [UI] 0·311–0·414) per 100 000. Mortality rates ranged from 1·01 (0·895–1·13) per 100 000 in central Latin America to 0·054 (0·0464–0·0617) per 100 000 in high-income Asia Pacific. …”
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131
The Impact of COVID-19 on the HIV Cascade of Care in Botswana – An Interrupted Time Series
Published 2024“…In multivariable Poisson interrupted time series regression, the COVID-19 lockdown was associated with a 27% decrease in the monthly numbers of HIV tests (IRR 0.73, 95%CI 0.72–0.73), a 25% decrease in HIV positive tests (IRR 0.75, 95%CI 0.71–0.79), and a 43% reduction in ART initiations (IRR 0.57, 95%CI 0.55–0.60). …”
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132
Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting
Published 2023“…Nonetheless, GWG in more than one-third of women who were overweight or obese exceeded the IOM recommendation.…”
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133
Independent and Combined Effects of Antioxidant Supplementation and Circuit Resistance Training on Selected Adipokines in Postmenopausal Women
Published 2019“…Our findings demonstrated that visfatin, vaspin, and leptin levels significantly decreased over the intervention period (all p < 0.05), with these values were lower in EG and ZMEG in comparison to CG at post-intervention (all p < 0.05). …”
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134
Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Published 2025“…InterpretationAlthough the burden attributable to HAP has decreased considerably, HAP remains a substantial risk factor, especially in sub-Saharan Africa and south Asia. …”
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135
Investigating the Impact of Salinity Variations on Aerobic Granules and Activated Sludge Flocs: Emphasis on Performance Monitoring and Identification of Influential Salinity Compon...
Published 2022“…These observations are more prevalent with unacclimated seed sludge. Moreover, most studies have been limited in the different salts used, reducing the ability to understand the characteristics of salinity (molar concentration, ionic strength, density etc) that leads to system failure. …”
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Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO<sub>2</sub>- saturated saline solution
Published 2023“…Nevertheless, the AGGPAM-inhibited solution exhibited a corrosion rate of 26.7 mils per year at 50 °C, which is still lower than that of blank at 25 °C. …”
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137
Bond durability of sand coated and ribbed basalt FRP bars embedded in high-strength concrete
Published 2023“…However, specimens with high-strength concrete achieved most of or above their maximum bond strength after the descending stage, while those with normal-strength concrete showed a decrease in bond strength to an approximately constant value with continuous slip. …”
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138
Blockchain, climate damage, and death: Policy interventions to reduce the carbon emissions, mortality, and net-zero implications of non-fungible tokens and Bitcoin
Published 2022“…With CO<sub>2</sub>-related deaths attributable to NFT transactions, social pressure from the art market has helped to progress the switch away from the deliberately polluting proof-of-work blockchains to more sustainable consensus protocols.</p><p dir="ltr">Nonetheless, many popular types of blockchain have resisted the pressure to decrease their environmental impact, including Bitcoin, whose attributed 2021 annual emissions will produce emissions responsible for around 19,000 future deaths. …”
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Salicylic acid restricts mercury translocation by activating strong antioxidant defense mechanisms in sweet pepper (Capsicum annum L.)
Published 2023“…., 0 μ M, 50 μ M, 100 μ M, and 150 μ M. The maximum decrease in photosynthetic machinery, plant growth attributes (shoot length, root length, no. of leaves, fresh and dry biomass (shoot and root)), and more accumulation of Hg in leaves, roots, and fruits of sweet pepper. …”
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New algorithm based active method to eliminate stick-slip vibrations in drill string systems
Published 2022“…This phenomenon can decrease the rate of penetration of drilling, wear of expensive equipment prematurely and cause catastrophic failures. …”