Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments حسب Gunjan Dagar (9339276)

"…Despite success in blood cancers, CAR-T technology faces challenges in solid tumors, including lack of reliable tumor-associated antigens, hypoxic cores, immunosuppressive tumor environments, enhanced reactive oxygen species, and decreased T-cell infiltration. To overcome these challenges, current research aims to identify reliable tumor-associated antigens and develop cost-effective, tumor microenvironment-specific CAR-T cells. …"

Soil Characterization Utilizing GPR Technique حسب Al Kej, Fateh Tamam

احصل على النص الكامل

Pavement Crack Assessment Using Satellite Remote Sensing and Deep Learning Model حسب Al Adab, Maryam

احصل على النص الكامل

Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021 حسب Comfort, Haley

"…Findings: In 2021, the global stillbirth rate was 23·0 (95% uncertainty interval [UI] 19·7–27·2) per 1000 births (stillbirths plus livebirths) at 20 weeks' gestation or longer, compared to 16·1 (13·9–19·0) per 1000 births at 28 weeks' gestation or longer. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 حسب Austin, Carter

"…In 2021, sub-Saharan Africa had the highest PUV of 999·9 (857·4–1154·2) per 100 000 population, but this was a 64·5% (58·8–69·4) reduction in PUV from 2003 to 2021. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations حسب Isra Marei (11312895)

"…<p dir="ltr">Despite the efforts devoted to drug discovery and development, the number of new drug approvals have been decreasing. Specifically, cardiovascular developments have been showing amongst the lowest levels of approvals. …"

Effect of Surface Treatment of Halloysite Nanotubes (HNTs) on the Kinetics of Epoxy Resin Cure with Amines حسب Vahideh Akbari (18768001)

"…<p dir="ltr">The epoxy/clay nanocomposites have been extensively considered over years because of their low cost and excellent performance. Halloysite nanotubes (HNTs) are unique 1D natural nanofillers with a hollow tubular shape and high aspect ratio. …"

Zirconium Phosphate/Ionic Liquid Proton Conductors for High Temperature Fuel Cell Applications حسب Mohammed, Hanin

احصل على النص الكامل

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership حسب JASIM, ARIF FADHEL AHMED

"…These interpretive cognitive acts of meaning construction by leaders and followers include significant elements of conceptual thinking and explanation. …"
احصل على النص الكامل

Implementation of corporate governance rules and procedures in lebanese firms حسب Elgammal, Walid

"…It also helps the organization to determine the means to achieve its objectives and monitor its performance. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th... حسب Jaimie D Steinmetz (18015919)

"…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global crude prevalence of avoidable vision impairment and blindness in adults aged 50 years and older did not change between 2010 and 2019 (percentage change −0·2% [95% UI −1·5 to 1·0]; 2019 prevalence 9·58 cases per 1000 people [95% IU 8·51 to 10·8], 2010 prevalence 96·0 cases per 1000 people [86·0 to 107·0]). …"

Essays on the effect of excess compensation and governance changes on firm value حسب Dah, Mustafa A.

"…The first paper utilizes a cost minimization stochastic frontier approach to investigate the efficiency of director total compensation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Enhanced thermoelectric properties of Bi₂Te_2.55Se_0.45 nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable... حسب Farah M. El-Makaty (14157090)

"…These results highlight EMS as a low-cost, natural nanofiller with strong potential for scalable thermoelectric applications.…"

Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO₂ intercooled and reheated cycles under design and off‐d... حسب Wahib A. Al‐Ammari (18877408)

"…The ICC has the minimum levelized cost of electricity compared to the other cycles with 5.93 ¢/kWh at design conditions (dry‐cooling), 5.65 ¢/kWh at optimized conditions (wet‐cooling), and 7.2 ¢/kWh at minimum PD (21 MW). …"

A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater حسب Azar, Riad

"…Recent series report 5-year postoperative survival rates of 53–68%.7 Successful endoscopic removal of high-grade intraepithelial neoplasia, in situ tumors, and focal T1 cancers has been reported, but is not widely practiced.8, 9 and 10 For patients with slow-growing benign tumors, endoscopic resection is an attractive alternative with decreased cost and morbidity.11 and 12 Endoscopic papillectomy has a recurrence rate of 30% with 13.9% of endoscopically treated patients subsequently undergoing follow-up surgery. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP) حسب Anas Hamad (9545771)

"…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. However, the cancer-related burden on patients, healthcare systems, and the economy is expected to expand; thus, cancer remains a significant public healthcare issue in Qatar. …"

Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Joseph L Ward (9715619)

"…Since 1950, deaths in this age group decreased by 30·0% in females and 15·3% in males, and sex-based differences in mortality rate have widened in most regions of the world. …"

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Hedyeh Ebrahimi (7321358)

"…Global age-standardised incidence rates of tracheal, bronchus, and lung cancer decreased by 7·4% (−16·8 to 1·6) and age-standardised incidence rates of larynx cancer decreased by 3·0% (−10·5 to 5·0) in males over the past decade; however, during the same period, age-standardised incidence rates in females increased by 0·9% (−8·2 to 10·2) for tracheal, bronchus, and lung cancer and decreased by 0·5% (−8·4 to 8·1) for larynx cancer. …"

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... حسب Michael, Brauer

"…Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2·5th and 97·5th percentile values across the draws. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study حسب Rajesh, Sharma

"…Its heightened risk calls for increased cancer awareness, preventive measures, affordable early-stage detection, and cost-effective therapeutics in Asia. The current study can serve as a useful resource for policymakers and researchers in Asia for devising interventions for cancer management and control. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل