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461
Case report: Safety and efficacy of voxelotor in a patient with sickle cell disease and stage IV chronic kidney disease
Published 2022“…Herein we report a 49-year-old man, with sickle cell disease and stage IV chronic kidney disease, who was managed successfully with voxelotor and resulted in decreasing transfusion requirement and vaso-occlusive painful crisis without affecting kidney function.…”
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462
On the Performance of the Node Control Volume Finite Element Method for Modeling Multi-phase Fluid Flow in Heterogeneous Porous Media
Published 2020“…</p><h2>Other Information</h2> <p> Published in: Transport in Porous Media<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s11242-020-01481-2" target="_blank">http://dx.doi.org/10.1007/s11242-020-01481-2</a></p>…”
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463
Successful minimally invasive management of nonvascular grade IV blunt renal trauma with complete transection in a 7-year-old girl
Published 2022“…Although such injuries have a decreased likelihood of spontaneous resolution, not all require open operative repair. …”
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464
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”
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465
12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
Published 2013“…Treatment of REC with HETE also increased ROS generation and expression of NOX2 and pVEGF-R2 and decreased pSHP1 expression. Treatment of diabetic mice with baicalein significantly decreased retinal HETE, ICAM-1, VCAM-1, IL-6, ROS generation, and NOX2 expression. …”
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466
Heat Shock-Related Protein Responses and Inflammatory Protein Changes Are Associated with Mild Prolonged Hypoglycemia
Published 2021“…At hypoglycemia, UBE2N, STIP1, and UBE2L3 increased (all p < 0.05), whilst TLR4:MD-2 and HSPA8 decreased (p < 0.05) in T2D versus baseline. In follow-up after hypoglycemia, HSPs normalized to baseline by 24 h, except UBE2L3 (p < 0.05), which was decreased in controls versus baseline. …”
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467
Effects of COVID-19 on Autism Spectrum Disorder in Qatar
Published 2024“…Parents also reported decreased access to family and social support networks, as well as decreased quality of clinical and community support. …”
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468
Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …”
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469
A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country
Published 2022“…Among SGLT2is, empagliflozin prescriptions showed an increase from 537 (10.65%) to 2881 (34.40%) compared to dapagliflozin, which decreased by the end of 2018 from 4505 (89.35%) to 5494 (65.6%).…”
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470
Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”
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471
Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort
Published 2024“…Elevated QTc was observed in CAD patients, whereas decreased QTc was correlated with decreased levels of calcium and potassium. …”
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472
Global time differences in road traffic injuries among children and adolescents between and 1990 and 2013: Regional and economical perspectives from global burden of diseases study
Published 2015“…Mortality rates for VRUs and nVRUs also decreased remarkably except among non-VRUs from LICs where the mortality rates increased by 16%. …”
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473
Thermal energy storage with phase change materials to increase the efficiency of solar photovoltaic modules
Published 2017“…The results show that, compared to the case without PCM module, the peak temperature of the solar module for a daily cycle can be decreased by approximately 20 K by an adequate design with a limited usage of metallic structure. …”
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474
Determining the influencing factors in the residential rooftop solar photovoltaic systems adoption: Evidence from a survey in Qatar
Published 2022“…<p>Renewable energy sources have developed rapidly, decreased in cost, and proven to have the potential to limit global warming. …”
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475
The influence of different preparation methods on the erosion behavior of NiP-ZrO<sub>2</sub> nanocomposite coating
Published 2023“…The results shows that the erosion rate decreases linearly with increasing angle of incidence and increases with increasing particle velocity. …”
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476
Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth
Published 2021“…The lowest number of functional groups occurred in the early ages (2–3 years old), and some groups either increased or decreased their frequency and abundance along the years. …”
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477
Adsorption of enhanced oil recovery polymer, schizophyllan, over carbonate minerals
Published 2020“…Our results indicate the adsorption capacity is higher on calcite and dolomite compared to silica and kaolin and the adsorption capacity decreases with salinity. Moreover, the adsorption kinetics follows pseudo-second order mechanism regardless of the mineral type. …”
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478
Run Rules-Based EWMA Charts for Efficient Monitoring of Profile Parameters
Published 2021“…</p><h2>Other Information</h2><p>Published in: IEEE Access<br>License: <a href="https://creativecommons.org/licenses/by/4.0/legalcode" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/access.2021.3061990" target="_blank">https://dx.doi.org/10.1109/access.2021.3061990</a></p>…”
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479
Acute spasticity in malignant MCA stroke: a case report and review of literature
Published 2025“…We report a case of a 40-year-old male patient who presented with spasticity accompanied by aphasia and decreased consciousness. Left MCA occlusion was demonstrated on Computed tomography (CT) angiography. …”
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480
Fast Sampling of Score-Based Models With Cyclical Diffusion Sampling
Published 2024“…</p><h2>Other Information</h2><p dir="ltr">Published in: IEEE Access<br>License: <a href="https://creativecommons.org/licenses/by-nc-nd/4.0/" target="_blank">https://creativecommons.org/licenses/by-nc-nd/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/access.2024.3365146" target="_blank">https://dx.doi.org/10.1109/access.2024.3365146</a></p>…”