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281
Exploring the LDHC Interactome as Novel Candidate Therapeutic Targets to Advance Breast Cancer Precision Medicine
منشور في 2024"…<p dir="ltr">Breast cancer remains a major health burden worldwide, being the second most commonly diagnosed cancer, and accounting for the highest cancer-related mortality rate among women. …"
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282
From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
منشور في 2025"…One of the notable elements in this connection is the “brain insulin resistance,” most frequently named as “type 3 diabetes,” which impairs glucose metabolism and facilitates amyloid beta (Aβ) plaque synthesis while reducing the action of insulin-degrading enzyme (IDE). …"
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283
Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study
منشور في 2024"…Preoperative color Doppler ultrasonography revealed absent or decreased testicular blood flow in the affected testes in 7/8 of patients. …"
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284
Phosphate-solubilizing bacteria-mediated rock phosphate utilization with poultry manure enhances soil nutrient dynamics and maize growth in semi-arid soil
منشور في 2025"…The integration of RP and PM, particularly with PSB inoculation, significantly (p < 0.05) improved soil and plant nitrogen (N), phosphorus (P), and potassium (K) levels. The most pronounced improvements were in the treatment with 90-RP + 6-PM + PSB, which increased soil total N by 285%, available P by 79%, and available K by 51%. …"
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285
Meta-Heuristic Algorithm-Tuned Neural Network for Breast Cancer Diagnosis Using Ultrasound Images
منشور في 2022"…<div><p>Breast cancer is the most menacing cancer among all types of cancer in women around the globe. …"
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286
Chiropractic manipulations gone wrong
منشور في 2016"…The prognosis of CeAD cases is generally good, with symptoms in most patients eventually resolving. However, significant neurologic complications or even death from a massive stroke occur in 2 to 5% of patients. …"
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287
Automatic image quality evaluation in digital radiography using for‐processing and for‐presentation images
منشور في 2024"…The expected positive effect that increasing IAK and decreasing tube potential should have on IQ was clearly exhibited in two IQ metrics only, the signal difference‐to‐noise‐ratio (SDNR) and the detectability index (d’), for both image types. …"
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288
Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
منشور في 2024"…However, agricultural areas decreased from 152.13 km<sup>2</sup> (18.5%) in 1980 to 140.38 km<sup>2</sup> (17%) in 2023, while barren lands decreased from 54.44 km<sup>2</sup> (6.6%) in 1980 to 34.71 km<sup>2</sup> (4.22%) in 2023. …"
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289
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
منشور في 2025"…Notable COX-2 inhibitory activities (IC<sub>50</sub> = 0.065–0.24 μM) were observed relative to celecoxib (IC<sub>50</sub> = 0.049 μM). The two most effective 15-LOX inhibitors, <b>2a</b> and <b>2b</b>, exhibited 69 % and 57% of quercetin's action, respectively. …"
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290
Evaluating the Successful Initiation of a New Dialysate Potassium Management Protocol: “Reduced Emergency Department Admission with Hyperkalemia in Hamad General Hospital Dialysis...
منشور في 2024"…Potassium disorders, hyperkalemia, and hypokalemia are the most common electrolyte disturbances associated with life threating arrhythmias among dialysis patients. …"
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291
Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study
منشور في 2024"…Tracheal, bronchus, and lung cancer (both sexes), breast cancer (among females), colon and rectum cancer (both sexes), stomach cancer (both sexes) and prostate cancer (among males) were among top-5 cancers in most Asian countries in terms of ASIR and ASMR in 2019 and cancers of liver, stomach, hodgkin lymphoma and esophageal cancer posted the most significant decreases in age-standardized rates between 1990 and 2019. …"
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292
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
منشور في 2024"…FindingsFrom 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. …"
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293
Genome-wide association study and meta-analysis of phytosterols identifies a novel locus for serum levels of campesterol
منشور في 2024"…The meta-analysis replicated most of the reported variants, and our study provided significant support for the association of variants in <i>SCARB1</i> and <i>ABO</i> with sitosterolemia. …"
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294
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
منشور في 2021"…Conclusion: Our results indicated a relatively high seroprevalence of B19V in Qatar. Most importantly, B19 DNA was detected among Qatari and non-Qatari blood donors. …"
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295
Machine Learning-Based Management of Electric Vehicles Charging: Towards Highly-Dispersed Fast Chargers
منشور في 2020"…LSTM provided the best results with an accuracy of 95% for predicting the most appropriate power rating (PR) for EVCS, followed by RF, DT, DNN, SVM, KNN, and NB. …"
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296
The investigation of treatment design parameters on carbon integration networks
منشور في 2023"…In fact, it has been previously reported in many studies that the most expensive step in Carbon Capture, Utilization and Sequestration (CCUS) is the treatment system. …"
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297
A Scoping Review to Find Out Worldwide COVID-19 Vaccine Hesitancy and Its Underlying Determinants
منشور في 2021"…Sometimes, several studies had been performed in the same country, and it was observed that vaccine hesitancy was high earlier and decreased over time with the hope of vaccine efficacy. …"
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298
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
منشور في 2024"…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild‐type CaM protein in the presence of Ca<sup>2+</sup>. …"
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299
Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
منشور في 2020"…The elderly population is the most susceptible to the negative effects of polypharmacy due to their altered pharmacokinetics and decreased drug clearance. …"
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300
Monitoring the Athlete Match Response: Can External Load Variables Predict Post-match Acute and Residual Fatigue in Soccer? A Systematic Review with Meta-analysis
منشور في 2019"…</p><h3>Conclusions</h3><p dir="ltr">Running distance above 5.5 m·s<sup>−1</sup> represents the most sensitive monitoring variable characterizing biochemical and neuromuscular responses, at least when assessed during the initial 24 h (not at 48 h/72 h) post-match recovery period. …"