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401
Case report: Safety and efficacy of voxelotor in a patient with sickle cell disease and stage IV chronic kidney disease
منشور في 2022"…The data about the safety and efficacy of voxelotor use in chronic kidney disease is limited. Herein we report a 49-year-old man, with sickle cell disease and stage IV chronic kidney disease, who was managed successfully with voxelotor and resulted in decreasing transfusion requirement and vaso-occlusive painful crisis without affecting kidney function.…"
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402
On the Performance of the Node Control Volume Finite Element Method for Modeling Multi-phase Fluid Flow in Heterogeneous Porous Media
منشور في 2020"…Large artificial fluid smearing is observed in coarse meshes; however, it decreases with the increase in mesh resolution. These findings prompt the use of high-resolution meshes for the method and the need for development of novel numerical methods to address this unphysical flow.…"
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403
Acute spasticity in malignant MCA stroke: a case report and review of literature
منشور في 2025"…The patient was a known smoker with androgenic anabolic steroid use. This case represents a rare presentation of malignant MCA infarction with acute spasticity and adds a unique aspect to the clinical spectrum of stroke presentation. …"
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404
The nexus between debt structure, firm performance, and the financial crisis: non-linear panel data evidence from Japan
منشور في 2022"…<p dir="ltr">This study seeks to analyze the non-linear relationship between a firm’s debt structure and performance based on evidence from Japan through the use of a panel data fixed effects model for a sample of 1,670 listed firms. …"
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405
Annual performance assessment of an off‐grid and self‐sufficient sustainable climate refuge for hot arid climates
منشور في 2023"…<p></p><div> <p>To overcome the problem of walking in the scorching heat and to encourage people to use more public transport (ie, trams and metros), the idea of sustainable climate refuge shelter is highly needed. …"
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406
Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy...
منشور في 2024"…For aetiology estimation, we used a counterfactual approach to quantify population-attributable fractions (PAFs). …"
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407
Road safety and traffic medicine in Iran: Achievements and challenges
منشور في 2015"…The number of annual fatalities, which had been on the rise for several decades, reached to the maximum number of over 27500 deaths in 2005. The number decreased to 23000 in 2010 and less than 18000 in 2013. …"
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408
Driving against the clock: Investigating the impacts of time pressure on taxi and non-professional drivers’ safety and compliance
منشور في 2024"…<p>Drivers often encounter time pressure, which can lead to riskier driving habits, decreased safety margins, and a higher chance of accidents. …"
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409
Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model
منشور في 2019"…<div><p>The use of chitosan nanoparticles (ChNPs) in various biological and environmental applications is attracting great interest. …"
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410
Qatar’s Evolving National Identity in Schools: A Twitter Perspective from 2015 to 2019
منشور في 2022"…This paper aims to address the issue of how schools are used as tools to instill the state’s vision of its own national identity. …"
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411
Role of Edge Groups in Defining the Stability of Aromatic Molecules Under Electron Irradiation
منشور في 2024"…The simulation results show that the binding energy of the thiol unit to the molecule decreases by more than 15% by including the CH<sub>2</sub> group. …"
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412
Prediction of critical total drawdown in sand production from gas wells: Machine learning approach
منشور في 2023"…This study used 23 datasets to develop the proposed models. …"
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413
Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments
منشور في 2023"…<div><p>Traditional cancer treatments use nonspecific drugs and monoclonal antibodies to target tumor cells. …"
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414
Effect of Mg incorporation on the properties of PCL/Mg composites for potential tissue engineering applications
منشور في 2024"…However, its low mechanical strength and slow biodegradation restrict its use in tissue engineering. Magnesium (Mg), a biocompatible metal with excellent osteoconductivity and biodegradability, is a promising choice for tissue engineering applications. …"
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415
Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies
منشور في 2021"…This review discusses the properties, characterization, profiling, and the diverse molecular mechanisms of circRNAs and their use as potential therapeutic targets in different human malignancies.…"
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416
Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
منشور في 2024"…A deterministic model was also used to describe NG transmission from clients to their spouses. …"
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417
Characterization of Electronic and Ionic Transport in Li<sub>1-</sub><sub><em>x</em></sub>Ni<sub>0.33</sub>Mn<sub>0.33</sub>Co<sub>0.33</sub>O<sub>2</sub>(NMC<sub>333</sub>) and Li...
منشور في 2016"…Here, the transport properties of NMC<sub>333</sub> and NMC<sub>523</sub> are investigated using impedance spectroscopy and DC polarization and depolarization techniques. …"
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418
Antibody‐based methods for the measurement of α‐synuclein concentration in human cerebrospinal fluid – method comparison and round robin study
منشور في 2018"…Each of the four methods showed high analytical precision, excellent correlation between laboratories (R2 0.83–0.99), and good correlation with each other (R2 0.64–0.93), although the slopes of the regression lines were different between the four immunoassays. The use of common reference CSF samples decreased the differences in α‐synuclein concentration between detection methods and technologies. …"
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419
Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials
منشور في 2020"…<h3>Background</h3><p dir="ltr">Angiotensin receptor blockers (ARBs) are commonly used as a treatment for many cardiovascular diseases, but their safety has been called into question. …"
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420
3D printing of circular materials: Comparative environmental analysis of materials and construction techniques
منشور في 2023"…The main environmental "hot spot" identified for the geopolymer-based 3D printed construction process was the amount of electrical energy required for the mechanical processing of waste materials, which was more than 61% of the total GWP impact. In addition to decreasing solid CDW, the developed approach has significant potential for improvement by using more sustainable energy sources and reducing the amount of solid CDW generated.…"