-
481
Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient
منشور في 2023"…LRBA was knocked down using siRNA in MIN6 cell line to investigate the role of LRBA in β-cells in more details. …"
-
482
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
منشور في 2020"…., shrinkage) on two deltas over the past 20 years, using Landsat-derived water masks. We find that monthly shrinkage rates have a pronounced structured variability around the channel network with the shrinkage rate systematically decreasing farther away from the channels. …"
احصل على النص الكامل
-
483
Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
منشور في 2022"…</p><h3>Methods</h3><p dir="ltr">In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. …"
-
484
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
منشور في 2022"…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …"
-
485
Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application
منشور في 2023"…Pharmacists can play a substantial role in decreasing the burden of the disease.</p><h3>Purpose</h3><p dir="ltr">The primary aim of this study was to develop and validate a scale assessing the pharmacist role in hypertension management in the community pharmacy setting. …"
-
486
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
منشور في 2024"…To capture time-series trends in CCF50 not explained by these covariates, we used a first-order autoregressive model on the residual term. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
487
Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud...
منشور في 2020"…Further, by doing a counterfactual analysis of the remaining disease burden using key risk factors, we identified potential intervention strategies for vulnerable populations. …"
-
488
Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
منشور في 2023"…The present pilot study represents a novel dietary means by which to reduce BCAA, and as such, provides a blueprint for a potential dietary therapeutic in obesity/diabetes.…"
-
489
Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17
منشور في 2020"…Many units were able to transition from the least safe facilities in 2000 to safe facilities by 2017; for units in which populations primarily practised open defecation in 2000, 686 (95% UI 664–711) of the 1830 (1797–1863) units transitioned to the use of improved sanitation. Geographical disparities in access to improved water across units decreased in 76·1% (95% UI 71·6–80·7) of countries from 2000 to 2017, and in 53·9% (50·6–59·6) of countries for access to improved sanitation, but remained evident subnationally in most countries in 2017. …"
-
490
Plasma volume variations in response to high intensity interval training in obese women: The influential role of menopausal status and age
منشور في 2025"…These measurements were derived using hematocrit (Ht) and hemoglobin (Hb) values. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
491
A Case Study in Qatar for Optimal Energy Management of an Autonomous Electric Vehicle Fast Charging Station with Multiple Renewable Energy and Storage Systems
منشور في 2020"…This interest has focused mainly on reducing the reliance on fossil fuel-based means of transportation and decreasing the harmful emissions produced from this sector. …"
-
492
Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
منشور في 2020"…To mimic hypertension, the rat portal vein (RPV) was mechanically stretched, and the protective effects of APN on mechanical stretch-induced vascular remodeling and the molecular mechanisms involved were examined by using 10 <i>μ</i>g/ml APN. Mechanically stretching the RPV significantly decreased APN protein expression after 24 hours and APN mRNA expression in a time-dependent manner in VSMCs. …"
-
493
LDL-C Targets in Secondary Prevention: How Low Should We Go?
منشور في 2019"…<h3>Abstract</h3><p dir="ltr">The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. …"
-
494
Thermal, electrical, and mechanical properties of highly filled HDPE/graphite nanoplatelets composites
منشور في 2020"…On the other hand, the degree of crystallinity and melting temperature decreased with GNPs content. The incorporation of GNPs greatly decreased the electrical resistivity by 10 orders of magnitude and 400% increase in thermal conductivity for filled HDPE was also observed. …"
-
495
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
منشور في 2025"…Protein structure was analyzed using circular dichroism (CD) spectroscopy and dynamic light scattering (DLS). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
496
Numerical investigation of MIL-101(Cr)/GrO composite performance in adsorption cooling systems
منشور في 2017"…The 5%GrO_phys composite showed a decreased SCP and an increased COP at the same cycle time. …"
-
497
Characterization of Electronic and Ionic Transport in Li<sub>1-</sub><sub><em>x</em></sub>Ni<sub>0.33</sub>Mn<sub>0.33</sub>Co<sub>0.33</sub>O<sub>2</sub>(NMC<sub>333</sub>) and Li...
منشور في 2016"…The lithium ion diffusivity is at least one order of magnitude lower, and decreases with increasing <i>x</i> to at <i>x</i> = ∼0.5. …"
-
498
Basin of Attraction through Invariant Curves and Dominant Functions
منشور في 2015"…We study a second-order difference equation of the form z<inf>n+1</inf> = z<inf>n</inf> F (z<inf>n-1</inf>) + h, where both F (z) and z F (z) are decreasing. We consider a set of invariant curves at h = 1 and use it to characterize the behaviour of solutions when h > 1 and when 0 < h < 1. …"
احصل على النص الكامل
احصل على النص الكامل
-
499
Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Global gene expression profiling was performed using the Agilent® microarray platform. Effects on in vivo ectopic bone formation were assessed by implanting hMSC mixed with hydroxyapatite-tricalcium phosphate granules subcutaneously in 8-week-old female nude mice, and the amount of bone formed was assessed using quantitative histology. …"
-
500
The therapeutic potential of matcha tea: A critical review on human and animal studies
منشور في 2023"…To date, randomized clinical trials (RCT) showed that matcha decreases stress, slightly enhances attention and memory, and has no effect on mood. …"