Chronic reduction of store operated Ca²⁺ entry is viable therapeutically but is associated with cardiovascular complications حسب Fang Yu (156838)

"…Here we address this issue using a novel genetic mouse model (SOCE hypomorph) with deficient SOCE, nuclear factor of activated T cells activation, and T cell cytokine production. …"

Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Esraa K. Al-Amleh (16023071)

"…Several treatments, including chemotherapy, radiation, hormone treatment, and immunological therapy, can be used to control this condition. The therapeutic impact on leukemic individuals varies, and the response to therapy varies between patients due to disease heterogeneity. …"

Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype... حسب Ilham Bettahi (363910)

"…The samples were processed using a quantitative proteomic analysis approach.…"

Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity حسب Abu Saleh Md Moin (6189512)

"…A hyperinsulinemic clamp was performed and normoglycemia induced in T2D [4.5 ± 0.07 mmol/L (81 ± 1.2 mg/dl)] for 1-h, following which blood glucose was decreased to ≤2.0 mmol/L (36 mg/dl). Proteomic analysis for the complement and coagulation cascades were measured using Slow Off-rate Modified Aptamer (SOMA)-scan.…"

Ratings of Perceived Exertion Misclassify Intensities for Sedentary Older Adults During Graded Cycling Test: Effect of Supramaximal High-Intensity Interval Training حسب Georges Jabbour (754884)

"…For both groups, RPE decreases with SCE at 10 min following graded test correlated significantly to V˙O₂ (r = 0.61, p < 0.01). …"

Masked phenomenon: renal and cardiovascular complications; review and updates حسب Elmukhtar Habas (14777677)

"…Normal blood pressure should be 120/80 mmHg, which generally decreases when a person is sleeping or sitting. High blood pressure or hypertension occurs when the blood pressure is too high. …"

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…<p dir="ltr">Dysregulated epigenetic modifications are common in lung cancer but have been reversed using demethylating agent like 5-Aza-CdR. 5-Aza-CdR induces/upregulates the NY-ESO-1 antigen in lung cancer. …"

Responding to Students' Writing in UAE Government Secondary Schools: Teachers' Attitudes and Practices, and Students' Perceptions حسب Abou Eissa, Aida Fares

احصل على النص الكامل

Modulation of gut microbiota: The effects of a fruits and vegetables supplement حسب Arun Prasath Lakshmanan (6807152)

"…The antioxidant capacity, measured by using the oxygen radical absorbance capacity (ORAC) method, was also slightly higher in the FVS group than in the PLA group but did not reach statistical significance. …"

Theoretical insight into effect of cation–anion pairs on CO₂ reduction on bismuth electrocatalysts حسب Sun Hee Yoon (7179263)

"…<p dir="ltr">This study presents theoretical insight into the mechanism of the CO₂ reduction reaction (CO₂RR) to formic acid (HCOOH) on Bi (0 1 2) surfaces in the presence of alkali metal cations (M⁺: Cs⁺, K⁺, and Li⁺) and/or halide anions (X⁻: Cl⁻, Br⁻, and I⁻) using density functional theory (DFT). The adsorption energy (Eads) and work function (Wf) of the anions increases with decreasing anion size (i.e., Cl⁻ > Br⁻ > I⁻). …"

Crystallization properties of arsenic doped GST alloys حسب Vinod E. Madhavan (8136774)

"…Structure properties of amorphous GST, Ge₂Sb_2−0.3As_0.3Te₅ and (GST)_0.85As_0.15 models were studied using first principles molecular dynamics simulations, compared their partial radial distribution functions, and q parameter order. …"

Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function حسب Sahar I. Da'as (17128747)

"…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild‐type CaM protein in the presence of Ca²⁺. …"

Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study حسب Ayman Al-Dahshan (8962568)

"…</p><h3>Methods </h3><p dir="ltr">A retrospective cross-sectional analysis was conducted using the Electronic Medical Record (EMR) database of all PHC centers in Qatar for six months (April-September 2017). …"

Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study حسب Ayman Al-Dahshan (8962568)

"…</p><h3>Methods </h3><p dir="ltr">A retrospective cross-sectional analysis was conducted using the Electronic Medical Record (EMR) database of all PHC centers in Qatar for six months (April-September 2017). …"

SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines حسب Hadeel T. Zedan (12535521)

"…Our data suggest that ADCC could be used to estimate the extra‐neutralization level against COVID‐19 and provides evidence that vaccination should focus on other Fc‐effector functions besides NAbs. …"

Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud... حسب Robert C Reiner (5147636)

"…Further, by doing a counterfactual analysis of the remaining disease burden using key risk factors, we identified potential intervention strategies for vulnerable populations. …"

Prognostic effects of cardiopulmonary resuscitation (CPR) start time and the interval between CPR to extracorporeal cardiopulmonary resuscitation (ECPR) on patient outcomes under e... حسب Amir Vahedian-Azimi (11177056)

"…These outcomes included longer CPR duration (OR: 1.779, 95%CI: 1.218–2.605, <i> P</i> = 0.034) and decreased survival rates for ECMO at 24 h (OR: 0.561, 95%CI: 0.183–0.903,<i> P</i> = 0.009) and 28 days (OR: 0.498, 95%CI: 0.106–0.802, <i> P</i> = 0.011). …"

Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1 حسب Natalie C Galles (9715361)

"…Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time.…"

Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 حسب Hmwe Hmwe Kyu (8674014)

"…</p><h3>Methods</h3><p dir="ltr">In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. …"

Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 حسب Natalia V, Bhattacharjee

"…To capture time-series trends in CCF50 not explained by these covariates, we used a first-order autoregressive model on the residual term. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل