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Showing 781 - 800 results of 878 for search '(((( three decrease ) OR ((( methrees decrease ) OR ( peters decrease ))))) OR ( mean decrease ))*', query time: 0.13s Refine Results
  1. 781

    Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease by Satra Nim (11540447)

    Published 2023
    “…We find that the most potent peptide inhibitor disrupts the direct interaction between the C-terminal region of α-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B), a component of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III). We show that α-synuclein impedes endolysosomal activity via this interaction, thereby inhibiting its own degradation. …”
  2. 782

    Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients by Asmaa Al-mansouri (16931739)

    Published 2021
    “…There was a strong negative correlation between TBQ score and KDQOL-36™ score [rs (251) = −0.616, p < 0.001], signifying that HR-QOL decreases as treatment burden increases.</p><h3>Conclusions</h3><p dir="ltr">This study suggests that a considerable proportion of CKD patients suffered from treatment-related burden and deterioration in HR-QOL at a varying degree of seriousness. …”
  3. 783

    Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments by Gunjan Dagar (9339276)

    Published 2023
    “…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Journal of Translational Medicine<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12967-023-04292-3" target="_blank">https://dx.doi.org/10.1186/s12967-023-04292-3</a></p>…”
  4. 784
  5. 785

    One-year experience of hybrid closed-loop system in children and adolescents with type 1 diabetes previously treated with multiple daily injections: drivers to successful outcomes by Goran Petrovski (129836)

    Published 2022
    “…The participants used the sensor 88.4 ± 6.5% of the time with Auto Mode usage 85.6 ± 7.4% during 12 months of HCL system use. HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline, to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at 3 months (p = 0.02) and remained stable to 7.1 ± 0.6 (54 ± 6.6 mmol/mol) at 12 months (p = 0.02). …”
  6. 786

    The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 20... by Sudabeh Alatab (11257335)

    Published 2020
    “…Findings In 2017, there were 6·8 million (95% UI 6·4–7·3) cases of IBD globally. The age-standardised prevalence rate increased from 79·5 (75·9–83·5) per 100 000 population in 1990 to 84·3 (79·2–89·9) per 100 000 population in 2017. …”
  7. 787
  8. 788

    From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease by Ahmad Raza (18205961)

    Published 2025
    “…Moreover, the overactivity of glycogen synthase kinase-3 beta (GSK-3β) also triggers taurine protein pathology. …”
  9. 789

    A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion by Issa, Elio

    Published 2023
    “…The collective’s role in fostering social support was evident through decreased fearful reactions. Many lost trust in the judicial system and favored emigration over standing for justice. …”
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  10. 790

    Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains by Riachi, Naji J.

    Published 1991
    “…We studied 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in 5 strains of rats by assessing mortality and brain monoamine changes after MPTP injections into the internal carotid artery. …”
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  11. 791

    Bulk passivation of perovskite films utilizing halide anion ionic liquids by Alashkar, Adnan

    Published 2023
    “…These values show that the presence of the IL with chloride anion greatly improves the average lifetime of the charge carrier by around 250%, while IL with iodide anion decreased the lifetime by 32% as compared with the pristine perovskite sample. …”
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  12. 792

    Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells by Mohamed Qasim, Al-Fahdawi

    Published 2021
    “…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …”
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  13. 793
  14. 794

    Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells by Sleiman, S.

    Published 2003
    “…The present study was designed to verify if human (h) Angiotensin II (Ang II) type-1 receptor (hAT1R) undergoes internalization, nuclear translocation, and de novo synthesis in primary culture of human aortic vascular smooth muscle cells (hVSMCs) and if overexpression of this receptor modulates sustained free cytosolic ([Ca]c) and nuclear ([Ca]n) calcium. 3-dimensional (3-D) confocal microscopy was used to monitor free intracellular Ca2+ and hAT1R-green fluorescence protein (GFP) fusion protein in cultured hVSMCs. …”
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  15. 795

    Breaking the barriers towards large-scale microalgae-based bio-hydrogen production by Isra Koko (22631396)

    Published 2025
    “…Results showed that cultivation dominates the process cost: typical biomass costs are $3.54–$5.78/kg in tubular PBRs versus $3.42–$4.13/kg in ORPs; an automation/modularization case decreased microalgae production cost from $89 to $16/kg at ∼200 t/yr. …”
  16. 796

    Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats by Maisa Siddiq Abduh (16381125)

    Published 2023
    “…Additionally, IL-35 or THYO decreased TNF-α, NF-κB, IL-10, IL-6 and IFN-γ in contrast to the PAR control group. …”
  17. 797

    Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Brittney S Sheena (9715568)

    Published 2022
    “…The number of HBV-related deaths increased between 1990 and 2019 (by 5·9% [–5·6 to 19·2]) and between 2015 and 2019 (by 2·9% [–5·9 to 11·3]). By contrast, all-age and age-standardised death rates due to HBV-related diseases decreased during these periods. …”
  18. 798

    Hippocampal Programmed Cell Death after Status Epilepticus by Abi-Habib, Ralph J.

    Published 2003
    “…Ceramide, a known mediator of PCD in multiple neural and nonneural tissues, increased at 2–3 h after KA intraperitoneal injection, and then decreased to control levels before increasing again from 12 to 30 h after injection. …”
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  19. 799

    Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer by Sampath, Lakshmi

    Published 2007
    “…The tumor-to-muscle ratio decreased in mice pretreated with trastuzumab and in mice injected with IRDye 800CW and (111In-DTPA)p-IgG-(IRDye800)q. …”
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  20. 800

    Trace element composition of size-fractionated suspended particulate matter samples from the Qatari Exclusive Economic Zone of the Arabian Gulf: the role of atmospheric dust by Oguz Yigiterhan (14151006)

    Published 2020
    “…Atmospheric dust in Qatar is depleted in Al and enriched in calcium (Ca), in the form of calcium carbonate (CaCO<sub>3</sub>), relative to the global average Upper Continental Crust (UCC). …”