Adaptation via altruistic mutations for all <i>k</i>. by Hanna Isaksson (747571)

“…Below the black lines mutations are not able to fix. For life cycles with a low value of <i>k</i>, e.g. binary fission, altruistic mutations spread in a large area that does not substantially vary with the environment. …”

Modelling of Large Protein Complexes by Patrick Bryant (11606596)

“…However, predicting protein complexes with more than a handful of chains is still unfeasible, as the accuracy rapidly decreases with the number of chains and the protein size is limited by the memory on a GPU. …”

The HMR complex components BOH1 and BOH2 largely colocalize with HMR in proximity to centromeres and HP1a domains (related to Fig 1). by Andrea Lukacs (3752956)

DataSheet_1_Large plants enhance aboveground biomass in arid natural forest and plantation along differential abiotic and biotic conditions.docx by Bai-Yu Yang (13952523)

“…Large plants increased slightly with increasing climatic water availability in the natural forest but decreased in plantation, whereas soil fertility inhibited large plants in plantation only. …”

Capturing the Transient Microstructure of a Physically Assembled Gel Subjected to Temperature and Large Deformation by Rosa Maria Badani Prado (11501833)

“…Here, we report the real-time change in the structure of physically assembled triblock copolymer gels that consist of 10 and 20 wt % of poly­(styrene)–poly­(isoprene)–poly­(styrene) [PS–PI–PS] triblock copolymer in mineral oil (i) during the gelation process with decreasing temperature, (ii) subjected to large oscillatory deformation, and (iii) during the stress-relaxation process after the application of a step strain. …”

Capturing the Transient Microstructure of a Physically Assembled Gel Subjected to Temperature and Large Deformation by Rosa Maria Badani Prado (11501833)

“…Here, we report the real-time change in the structure of physically assembled triblock copolymer gels that consist of 10 and 20 wt % of poly­(styrene)–poly­(isoprene)–poly­(styrene) [PS–PI–PS] triblock copolymer in mineral oil (i) during the gelation process with decreasing temperature, (ii) subjected to large oscillatory deformation, and (iii) during the stress-relaxation process after the application of a step strain. …”

<i>N</i>. <i>bombycis</i> infected oocyte from the follicle and nurse cells. by Chunxia Wang (766713)

TEM demonstrated the infection of follicle and nurse cells by <i>N</i>. <i>bombycis</i>. by Chunxia Wang (766713)

Data_Sheet_1_The Proximal Drivers of Large Fires: A Pyrogeographic Study.docx by Hamish Clarke (8666307)

“…As in most fire-prone environments, the majority of annual burned area is due to a relatively small number of large fires. We train and test an Artificial Neural Network’s ability to predict spatial patterns in the probability of large fires (>1,250 ha) in forests and grasslands as a function of proxies of the four major controls on fire activity. …”

Addition of <i>precA</i> decreases the sensitivity of <i>rarA ruvB</i> cells to DNA damage. by Kanika Jain (2884439)

Extreme morphological adaptations to accommodate large teeth in fish jaws. by Nick Peoples (21593888)

Structural en-face optical coherence tomography angiography images of an intermediate age-related macular degeneration eye, showing large choroidal vessels (LCV) within the chorioc... by Valentin Hacker (9956024)

Rotation of a CLSM acquisition showing the large decrease in cathepsin D decoration of <i>L</i>.... by Sandrine Cojean (274005)

Species richness (<i>SR</i>, upper panels) and Shannon’s entropy (<i>SE</i>, lower panels) vs. the rate in which new species are trying to invade the community, <i>νN</i>. by Immanuel Meyer (12306666)

“…A comparison between the case of <i>Q</i> = 10 [panels (b) and (e)] and <i>Q</i> = 3 [panels (a) and (d)] suggest that the crossover from the storage-dominated regime, where global competition is better, to the regime in which global competition acts to decrease biodiversity, occurs when the number of species is equal to the number of temporal niches. …”

Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma by Hao Shi (158171)

“…</p> <p><b>Abbreviation</b>: 3-MA, 3-methyladenine; AL, autolysosome; AP, autophagosome; Baf-A1, bafilomycin A₁; BARA, β-α repeated autophagy specific domain; BH3, BCL2 homology 3 domain; CCD, coiled-coil domain; CHX, cycloheximide; Co-IP, co-immunoprecipitation; CQ, chloroquine; CTR, control; DAPI, 4′,6-diamidino-2-phenylindole; EBSS, Earle’s balanced salt solution; ECD, evolutionarily conserved domain; EEE, three-tyrosine phosphomimetic mutations Y229E Y233E Y352E; ER, endoplasmic reticulum; FFF, three-tyrosine non-phosphomimetic mutations; FFPE, formalin-fixed paraffin-embedded; FL, full-length; GIST, gastrointestinal stromal tumor; IB, immunoblotting; IHC, immunohistochemistry; KIT-HEK293, KIT stably expressing HEK293 cells; KRT20/CK20, keratin 20; LT, large T-antigen; LT339, MCPyV truncated LT antigen; LTco, codon-optimized MCPyV LT antigen; MCC, Merkel cell carcinoma; MCPyV⁻, MCPyV-negative; MCPyV, Merkel cell polyomavirus; MCPyV⁺, MCPyV-positive; PARP1, poly(ADP-ribose) polymerase 1; PCI, pan-caspase inhibitor; PI, propidium iodide; PtdIns3K, class III phosphatidylinositol 3-kinase; PtdIns3P, phosphatidylinositol-3-phosphate; RB1, RB transcriptional corepressor 1; RTKs, receptor tyrosine kinases; KITLG/SCF, KIT ligand; sT, small T-antigen; sTco, codon-optimized MCPyV sT antigen; T-B, Tat-BECN1; T-S, Tat-scrambled; TEM, transmission electron microscopy.…”

VACV sA28 and sH2 <i>in vitro</i> protein binding analyses. by Chi-Fei Kao (11414234)

Data Sheet 1_Large, but short-term, increase in fecal indicator bacteria following extreme flooding from Hurricane Harvey in Houston, TX.docx by Maitreyee Mukherjee (10860393)

DataSheet_1_Year-round foraging across large spatial scales suggest that bowhead whales have the potential to adapt to climate change.pdf by Sarah M. E. Fortune (4610563)

“…Our findings suggest that, compared to related species (e.g., right whales), bowheads forage at relatively low rates and over a large geographic area throughout the year. This suggests that bowhead whales have the potential to adjust their behaviours (e.g., increased time allocated to feeding) and shift their distributions (e.g., occupy higher latitude foraging grounds) to adapt to climate-change induced environmental conditions. …”

<b>Supporting data for manuscript</b> "<b>Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins</b>" by Kira Shaw (18796168)

“…<p dir="ltr">The CSV file 'Eyreetal_DrainingVein_SourceData' contains the averaged time series traces and extracted metrics from individual experiments used across Figures 1-5 in the manuscript "Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins". …”

3D reconstruction from confocal planes (thresholded for Nemp1 intensity to emphasize Nemp1 aggregates, top panels) of erythroblasts undergoing a large nuclear envelope opening. by Didier Hodzic (132944)