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581
Source data.
Published 2025“…Under wide-field imaging in primary somatosensory and visual cortices in mice with high labeling density (80–90%), SomaFRCaMPi exhibits up to 40% higher SNR and decreased artifactual correlation across neurons. Altogether, SomaFRCaMPi improves the accuracy and scale of neuronal activity imaging at single-neuron resolution in densely labeled brain tissues due to a 2–3-fold enhanced automated neuronal segmentation, 50% higher fraction of responsive cells, up to 2-fold higher SNR compared to jRGECO1a. …”
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582
In vitro biophysical properties of red GECIs.
Published 2025“…Under wide-field imaging in primary somatosensory and visual cortices in mice with high labeling density (80–90%), SomaFRCaMPi exhibits up to 40% higher SNR and decreased artifactual correlation across neurons. Altogether, SomaFRCaMPi improves the accuracy and scale of neuronal activity imaging at single-neuron resolution in densely labeled brain tissues due to a 2–3-fold enhanced automated neuronal segmentation, 50% higher fraction of responsive cells, up to 2-fold higher SNR compared to jRGECO1a. …”
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583
Source data.
Published 2025“…Under wide-field imaging in primary somatosensory and visual cortices in mice with high labeling density (80–90%), SomaFRCaMPi exhibits up to 40% higher SNR and decreased artifactual correlation across neurons. Altogether, SomaFRCaMPi improves the accuracy and scale of neuronal activity imaging at single-neuron resolution in densely labeled brain tissues due to a 2–3-fold enhanced automated neuronal segmentation, 50% higher fraction of responsive cells, up to 2-fold higher SNR compared to jRGECO1a. …”
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584
2526 Epitope Mapping for influenza HA, SARS-CoV-2 spike, and HIV-1 Env.
Published 2024“…Removal of the stem glycan N23 dramatically decreased binding. WT, wild type HA. (B) 2526 was tested against full SARS-CoV-2 spike as well as subunit constructs in an ELISA format, binding strongly to the full spike as well as the N-terminal domain (NTD) construct. …”
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585
Supplementary Material for: Head positioning for stroke blood flow augmentation assisting reperfusion therapies (HEAD-START) study
Published 2025“…Trendelenburg positioning was maintained for 24h if lesion volume significantly decreased (≥5mL) and stroke reperfusion was suboptimal or undetermined. …”
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586
Structure–Activity Relationships and Discovery of (<i>S</i>)‑5‑(<i>tert</i>-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2′,1′:2,3]imidazo[4,5‑<i>h</i>]quin...
Published 2024“…Optimization of a novel series of PAPD5/7 inhibitors that decrease HBsAg levels led to the tetracyclic 2-pyridone <b>AB-161</b>, which was similarly potent to <b>AB-452</b> <i>in vitro</i> and <i>in vivo</i> but showed dramatically higher rodent liver-to-plasma ratios. …”
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587
Data Sheet 1_Gut microbiota interacting with vitamin D but not anandamide might contribute to the pathogenesis of preeclampsia: a preliminary study.pdf
Published 2025“…Compared with the LP group, the relative abundances of Prevotella, Erysipelotrichaceae_UCG-003, and Dorea were increased dramatically in the PE group, whereas the relative abundances of Subdoligranulum, Parabacteroides, Bacteroides were significantly decreased in the PE group. …”
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588
Data Sheet 1_Thermodynamic integration in combined fuel and power plants producing low carbon hydrogen and power with CCUS.docx
Published 2024“…<p>Demand for low-carbon sources of hydrogen and power is expected to rise dramatically in the coming years. Individually, steam methane reformers (SMRs) and combined cycle gas power plants (CCGTs), when combined with carbon capture utilisation and storage (CCUS), can produce large quantities of on-demand decarbonised hydrogen and power respectively. …”
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589
Data from: Long-lived winter honey bees show unexpectedly high levels of flight activity compared to short-lived summer bees
Published 2024“…<p dir="ltr">This dataset results from the automated RFID monitoring of honey bees marked throughout the year, from 2021-05-21, to 2022-04-27. …”
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590
Supplementary Material for: Effect of Surface Perturbation Treadmill Training Program on Strategies and Kinematics of Reactive Stepping during Standing in Older Adults: A Single-Bl...
Published 2025“…Introduction: perturbation-based balance training reduces fall rates dramatically by triggering and improving balance recovery skills. …”
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591
Table_1_Feasibility and assessment of self-reported dietary recalls among newly diagnosed multiple sclerosis: a quasi-experimental pilot study.docx
Published 2024“…From baseline to 12 months, the HB group had a decreased mean ratio in total grains (0.64; 95% CI 0.43–0.93; p = 0.02) and added sugars (0.52; 95% CI 0.35–0.75; p ≤ 0.001), and an increased mean ratio intake of cured meats (1.74; 95% CI 1.05–2.90; p = 0.04); whereas, the SOC group had a decreased mean ratio intake for beef, veal, pork, lamb, and game meat (0.60; 95% CI 0.40–0.90; p = 0.01). …”
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592
Data Sheet 1_Machine-learning detection of stress severity expressed on a continuous scale using acoustic, verbal, visual, and physiological data: lessons learned.pdf
Published 2025“…Resources needed may be decreased using automatization of experimental procedures, which may, however, lead to additional technological challenges, potentially causing other recruitment setbacks. …”
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593
Applications of Human Biostasis in Crewed Space Exploration
Published 2025“…This reduction allows for smaller habitat designs, lighter spacecraft, and decreased fuel needs, ultimately reducing mission costs. …”
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594
Additional file 1 of Deficiency in nucleoside diphosphate kinase B leads to endothelial activation of the hexosamine biosynthesis pathway and cardiac dysfunction
Published 2025“…Beating rates of CMs decrease dramatically in NDPKB-depleted hiPSC-CMs. …”
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595
Data inputs for BKMR.
Published 2025“…Over the past two decades, China has dramatically reduced maternal mortality in more developed (eastern) and less developed (western) regions. …”
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596
Digitized maps of vascular plant species distributions in Denmark in the early 20th century
Published 2025“…By comparing with modern distribution data, species increases and decreases can be determined, contributing to large-scale synthesis of national, European or worldwide plant diversity changes in the modern era.…”
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597
Graphical overview of study.
Published 2024“…Database-based complex-centric approaches (<i>middle</i>) are automated workflows, which compare the abundance of known protein complexes. …”
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598
Effects of activators and inhibitors on TcPiezo channels.
Published 2025“…Addition of 20 µ M Yoda1 (+Yoda1) dramatically stimulated TcPiezo2-mediated Ca<sup>2+</sup> release from lysosomes. …”
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599
<b>Data from: </b><b>Experimentally increased food availability allows for earlier departure in a long-distance migratory shorebird</b>
Published 2025“…Food accessibility was controlled by using automated cat feeders (Cat Mate C300, closerpets.eu) that open and close at set times. …”
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600
<b>Distributed Hydraulic Micro-Cooling (MHD): A Low-Cost, High-Impact Urban Heat Mitigation Strategy</b> / <b>Enfriamiento Hidráulico Micro-Distribuido (MHD): Estrategia Urbana de...
Published 2025“…</li><li><b>Urban Heat Island Mitigation</b><br>Reducing stored surface heat by even <b>5–10%</b> leads to measurable decreases of <b>1–3°C</b> in near-surface ambient air temperature. …”