Metformin: Is it a drug for all reasons and diseases? by Chris R. Triggle (4278688)

“…It remains unclear as to whether all of these putative beneficial effects are secondary to its actions as an anti-hyperglycemic and insulin-sensitizing drug, or result from other cellular actions, including inhibition of mTOR (mammalian target for rapamycin), or direct anti-viral actions. Clarification is also sought as to whether data from ex vivo studies based on the use of high concentrations of metformin can be translated into clinical benefits, or whether they reflect a ‘Paracelsus’ effect. …”

Regular, Intense Exercise Training as a Healthy Aging Lifestyle Strategy: Preventing DNA Damage, Telomere Shortening and Adverse DNA Methylation Changes Over a Lifetime by Maha Sellami (4351159)

“…Methylation and histone acetylation are two of the most well-studied examples of the epigenetic modifications that occur on histone proteins. DNA methylation is the type of epigenetic modification that alters gene expression without modifying gene sequence. …”

Functionalized Metal Organic Frameworks For Chemotherapy Drug Delivery by Ahmed, Ahmed H.S

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Ion-imprinted membranes for lithium recovery: A review by Sifani Zavahir (1657531)

“…The review thoroughly investigates the application of IIMs in Li extraction, covering extensive sections on 12-crown-4 ether (a fundamental crown ether for Li), its modifications, calixarenes, and other materials for creating imprinting sites. …”

Timing influenced general-cell genetic floorplanner by Sait, Sadiq M.

“…The second phase allows modification to the aspect ratios of individual modules to reduce further the area of the overall bounding box. …”
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A forward-backward Kalman for the estimation of time-variant channels in OFDM by Al-Naffouri, T.Y.

“…We also suggest a suboptimal modification that is able to track the channel and recover the data with no latency.…”
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A New Parallel Genetic Algorithm Model by Al-Somani, Turki F.

“…This paper presents an implementation of three Genetic Algorithm models for solving a reliability optimization problem for a redundancy system with several failure modes, a modification on a parallel a genetic algorithm model and a new parallel genetic algorithm model. …”
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On friction regimes in quantitative elastohydrodynamics by Habchi, W.

“…The measured thermo-physical properties of the oil are used without any modification to force agreement with experiments. The authors propose four friction regimes delimited by the combined values of three dimensionless parameters.…”
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Mechanistic basis of phenothiazine‐driven inhibition of Tau aggregation by Akoury, Elias

“…Phenothiazines, such as methylene blue and its azure derivatives, have a unique mechanism, specifically modifying the Tau cysteine residues. The modification keeps Tau in a monomeric disordered conformation preventing the formation of filaments and their toxic precursors.…”
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Effect of fibre volume on tensile properties of real unidirectional fibre-reinforced composites by Karam, G.N.

“…Based on the reduction of interfacial surfaces due to fibre-fibre interaction, a modification to the rule of mixtures is proposed. The experimentally observed non-linear variation of tensile strength with fibre volume can be predicted by the modified rule. …”
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"Building Information Modeling (BIM)” Implementation in Construction project and its effects in dispute avoidance and resolution by ALGHAZALI, WESAM M J

“…This research has highlighted the implementation of BIM for the purpose of dispute avoidance. Moreover, the modification in the standard form of contracts and in the legal systems in the process of BIM adoption has also been clearly discussed in this study. …”
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A Study on the Innovative Business Strategies Adopted by Different Firms in the Construction Industry during the Global Economic Crisis in the U.A.E by Gafoor, Neyas Abdul

“…Various strategic approaches adopted, at the time of recession, by the companies in the construction sector, were studied; the modification of strategies appropriately can maintain or improve their performance in time of crisis.…”
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... by Muhanad Alhujaily (11630107)

“…Spliceosomal proteins were targets of MG modification. Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. …”

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal by Zehra Irshad (18614869)

“…Flux of glucose metabolism, MG formation and glycation and changes in cytosolic protein abundances, MG modification and proteotoxic responses were assessed. …”

Application of behavioural theories, models, and frameworks in pharmacy practice research based on published evidence: a scoping review by Zachariah Nazar (8600154)

“…Few studies provided explicit and comprehensive justification for adopting a specific theory/model/framework and description of how it underpinned the research was lacking. …”

Micropolitics. (c2010) by Qatami, Nasser al-

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NFTs for the Unassailable Authentication of IoT Devices in Cyber-Physical Systems: An Implementation Study by Usman Khalil (7820876)

“…The deployment process culminates in the generation of NonFungible Tokens (NFTs) for user authentication, with transaction verification on the Goerli testnet confirming successful DSCoT edge system implementation. …”

A Novel Encryption Method for Dorsal Hand Vein Images on a Microcomputer by M. Z. Yildiz (16855476)

“…The results of the analysis have shown that the proposed encryption algorithm can be used in identification and verification systems. The encrypted images were analyzed with histogram, correlation, entropy, pixel change rate (NPCR), initial condition sensitivity, data loss, and noise attacks which are frequently used for security analyses in the literature. …”

Design of Secure and Efficient Framework for Vehicular Digital Twin Networks Using ECC by Vinod Kumar (48743)

“…In addition, the paper discusses formal and informal security analysis based on the random oracle model, Burrows-Abadi Needham (BAN) logic, and Scyther verification tool. The proposed protocol ensures security, privacy, and other related security attacks and attributes in VDT networks. …”

LNCRI: Long Non-Coding RNA Identifier in Multiple Species by Saleh Musleh (15279190)

“…However, the cost and time-consuming nature of transcriptomics verification techniques barred the research community from focusing on lncRNA identification. …”