Effects ofS-nitroso-N-acetylcysteine on contractile function of reperfused skeletal muscle by Nasser, Rima M.

“…However, it has become apparent that the success of replantation and microsurgical reconstructive operations should not be measured by survival alone but also by quantification of subsequent function. The ultimate goal is to regain normal function or, at least, to improve impaired function. …”
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Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans by Kevin S. Chen (9201767)

“…Next, we devised a method for semi-automated and blinded quantification of motor impairment for a population of simultaneously recorded animals with multi-worm tracking and custom image processing. …”

Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case Study by Alaa Abd-alrazaq (17058018)

“…Furthermore, future studies could evaluate more efficient modeling algorithms, especially those combining topic modeling with statistical uncertainty quantification, such as conformal prediction.</p><h2>Other Information</h2><p dir="ltr">Published in: JMIR Formative Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2196/49411" target="_blank">https://dx.doi.org/10.2196/49411</a></p>…”

Global, regional, and national sex differences in the global burden of tuberculosis by HIV status, 1990–2019: results from the Global Burden of Disease Study 2019 by Jorge R Ledesma (9715460)

“…A compartmental meta-regression tool (DisMod-MR 2.1) was then used to synthesise all available data sources, including prevalence surveys, annual case notifications, population-based tuberculin surveys, and tuberculosis cause-specific mortality, to produce estimates of incidence, prevalence, and mortality that were internally consistent. …”

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration by Megan F. Duffy (5713772)

“…</p><h3>Methods</h3><p dir="ltr">Male Fischer 344 rats (<i>N</i> = 114) received unilateral intrastriatal injections of α-syn PFFs, PBS, or rat serum albumin with cohorts euthanized at monthly intervals up to 6 months. Quantification of dopamine neurons, total neurons, phosphorylated α-syn (pS129) aggregates, major histocompatibility complex-II (MHC-II) antigen-presenting microglia, and ionized calcium-binding adaptor molecule-1 (Iba-1) immunoreactive microglial soma size was performed in the substantia nigra. …”

Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Christopher J L Murray (13580635)

“…<p>Background Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. …”