Image 1_Pharmacogenetic variations and clinical implications of actionable CYP2D6/CYP2C19 variants in Central Indian patients with common mental disorders.tif по Santenna Chenchula (14775163)

“...Overall, 7.5% of patients carried CYP2D6 variants and 20.6% carried CYP2C19 variants, for which CPIC guidelines recommend alternative drug selection or dose modification.</p>Discussion<p>This study demonstrates a high prevalence of actionable CYP2D6 and CYP2C19 variants in the Central Indian population, underscoring the need for pharmacogenetic integration in psychiatric prescribing in Indian clinical settings, to enhance treatment efficacy and minimize adverse events....”

Table 2_Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacement.xlsx по Xiao-Yi Xiong (8552478)

“...Both MG and Mo/MΦ experience modification of immune responses after microglial repopulation, with more prominent changes in MG. ...”

Table 6_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.csv по Xiaofeng Li (342614)

“...Aberrant crotonylation, a type of epigenetic modification, has been implicated in the proliferation, metastasis, and immune evasion of various cancers. ...”

Data Sheet 1_Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: eviden... по Matej Stuhec (5643284)

“...The study included inpatients aged ≥65 years with mental disorders who were referred for medication reviews between 2013 and 2018 and had at least one therapy modification related to somatic comorbidities (heart failure, arterial hypertension, or diabetes). ...”

Data Sheet 1_Pharmacogenetic variations and clinical implications of actionable CYP2D6/CYP2C19 variants in Central Indian patients with common mental disorders.pdf по Santenna Chenchula (14775163)

“...Overall, 7.5% of patients carried CYP2D6 variants and 20.6% carried CYP2C19 variants, for which CPIC guidelines recommend alternative drug selection or dose modification.</p>Discussion<p>This study demonstrates a high prevalence of actionable CYP2D6 and CYP2C19 variants in the Central Indian population, underscoring the need for pharmacogenetic integration in psychiatric prescribing in Indian clinical settings, to enhance treatment efficacy and minimize adverse events....”

Table 3_Short-term heavy drinking in a non-human primate model skews monocytes toward a hypo-inflammatory phenotype.xlsx по Madison B. Blanton (21583589)

“...These changes may be driven by reduced levels of H3k4me3, a histone modification shown to be deposited at promoter regions of genes involved in inflammation and pathogen response signaling....”

Table 2_Short-term heavy drinking in a non-human primate model skews monocytes toward a hypo-inflammatory phenotype.xlsx по Madison B. Blanton (21583589)

“...These changes may be driven by reduced levels of H3k4me3, a histone modification shown to be deposited at promoter regions of genes involved in inflammation and pathogen response signaling....”

Table 3_The association of exogenous dietary antioxidant micronutrient intake and consumption timing with urinary albumin excretion among U.S. adults.xls по Hangxu Li (20457785)

“...Subgroup analysis revealed effect modification by BMI: the protective association was attenuated in participants with obesity (BMI ≥ 30)....”

Table 2_The association of exogenous dietary antioxidant micronutrient intake and consumption timing with urinary albumin excretion among U.S. adults.docx по Hangxu Li (20457785)

“...Subgroup analysis revealed effect modification by BMI: the protective association was attenuated in participants with obesity (BMI ≥ 30)....”

Image 1_Association between controlling nutritional status score and mortality in older patients with dysphagia in Japan: a retrospective cohort study.tif по Yan Wang (15435)

“...Mortality associations were assessed through multivariable Cox proportional hazards models, with subgroup analyses conducted to evaluate effect modification. Survival patterns were visualized using Kaplan-Meier methodology. ...”

Table 1_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.xlsx по Xiaofeng Li (342614)

“...Aberrant crotonylation, a type of epigenetic modification, has been implicated in the proliferation, metastasis, and immune evasion of various cancers. ...”

Table 1_The association of exogenous dietary antioxidant micronutrient intake and consumption timing with urinary albumin excretion among U.S. adults.docx по Hangxu Li (20457785)

“...Subgroup analysis revealed effect modification by BMI: the protective association was attenuated in participants with obesity (BMI ≥ 30)....”

Two-Photon Polymerization of Bioinspired Microstructure with Tunable Wettability Controlled by Dielectric Elastomer Actuator по Zefu Ren (14268389)

“...In addition, the DEA-induced programmable microstructure enabled surface adhesion modification, allowing droplet manipulation and transportation. ...”

Supplementary file 1_Dietary breadth and ecological plasticity facilitate invasion potential in a large omnivorous lizard.docx по Madison E. A. Harman (22821428)

“...<p>Invasive species are a widely recognized threat to ecosystems, where they can negatively affect native species through mechanisms such as predation, competition, and ecosystem modification, including altering seed dispersal. Quantifying these effects is essential to properly assess risk and inform management efforts. ...”

Data Sheet 1_Evaluation of the levels of interleukins IL-4, IL-13, IL-5, IL-10 and IL-33 in atopic dermatitis patients with and without dupilumab therapy.docx по Jarmila Čelakovská (17116060)

“...Nonparametric Kruskal-Wallis analysis of variance with post-hoc Dunn’s test with Bonferroni modification of significance level was used.</p>Results<p>The significantly higher plasma level of stimulated IL-5 was confirmed in AD patients treated with dupilumab and significantly higher plasma IL-10 levels were confirmed in both dupilumab and non-dupilumab treated patients compared to control group. ...”

HLQ domain description and item order. по Muslim Abbas Syed (18593839)

“...</p><p>Discussion</p><p>Evidence generated from the study can increase health literacy levels among service users by modification of health behavior through effective health education. ...”

Data Sheet 1_Association of triglyceride glucose body mass index with osteoporosis risks in a large Chinese adult cohort.docx по Hongshun Liu (22293508)

“...Stratified analyses were performed to explore the effect modification by age, sex, renal function, smoking, and medication use....”

Enhancing Astaxanthin Biosynthesis in Synthetic Yeast Through Combinatorial Metabolic Engineering and Genome-Scale Evolution по Shuilian Guo (22139679)

“...Through combinatorial implementation of genome-scale diversification using the Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) system coupled with an absorption-based semi-high-throughput screening platform (<i>A</i>₄₅₀/<i>A</i>₆₀₀), we successfully isolated an elite mutant strain, YgM97, that achieved 6.85 mg/L astaxanthin production in shake-flask culture. ...”

Multiphoton Luminescence Imaging: A Label-Free Tool for Visualizing the Long-Term Fate of Gold Nanoparticles in Tissue по Sean Burkitt (21983541)

“...We demonstrate that MPL imaging detects up to 98% more AuNP-positive regions than brightfield microscopy in challenging low-dose (1 nM) conditions and requires no modification of standard histology workflows. Correlative imaging with SEM–EDS confirms high spatial specificity (AUC = 0.955) of MPL for AuNP localization. ...”

Image 10_Succinylation heterogeneity in lung adenocarcinoma: from prognostic model to KLK6-driven tumor microenvironment remodeling.tif по Jichang Liu (1263291)

“...Protein succinylation, a key post-translational modification, is implicated in tumor progression. However, its comprehensive landscape and clinical significance in LUAD remain largely unexplored....”