A mostrar 4,281 - 4,300 resultados de 4,391 para a pesquisa '((((justification OR justification) OR purification) OR modifications) OR codification)', tempo de pesquisa: 0.12seg Refinar resultados
  1. 4281

    Supplementary file 1_Dietary breadth and ecological plasticity facilitate invasion potential in a large omnivorous lizard.docx Por Madison E. A. Harman (22821428)

    Publicado em 2025
    “...<p>Invasive species are a widely recognized threat to ecosystems, where they can negatively affect native species through mechanisms such as predation, competition, and ecosystem modification, including altering seed dispersal. Quantifying these effects is essential to properly assess risk and inform management efforts. ...”
  2. 4282

    Data Sheet 1_Evaluation of the levels of interleukins IL-4, IL-13, IL-5, IL-10 and IL-33 in atopic dermatitis patients with and without dupilumab therapy.docx Por Jarmila Čelakovská (17116060)

    Publicado em 2025
    “...Nonparametric Kruskal-Wallis analysis of variance with post-hoc Dunn’s test with Bonferroni modification of significance level was used.</p>Results<p>The significantly higher plasma level of stimulated IL-5 was confirmed in AD patients treated with dupilumab and significantly higher plasma IL-10 levels were confirmed in both dupilumab and non-dupilumab treated patients compared to control group. ...”
  3. 4283

    HLQ domain description and item order. Por Muslim Abbas Syed (18593839)

    Publicado em 2025
    “...</p><p>Discussion</p><p>Evidence generated from the study can increase health literacy levels among service users by modification of health behavior through effective health education. ...”
  4. 4284

    Data Sheet 1_Association of triglyceride glucose body mass index with osteoporosis risks in a large Chinese adult cohort.docx Por Hongshun Liu (22293508)

    Publicado em 2025
    “...Stratified analyses were performed to explore the effect modification by age, sex, renal function, smoking, and medication use....”
  5. 4285

    Enhancing Astaxanthin Biosynthesis in Synthetic Yeast Through Combinatorial Metabolic Engineering and Genome-Scale Evolution Por Shuilian Guo (22139679)

    Publicado em 2025
    “...Through combinatorial implementation of genome-scale diversification using the Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) system coupled with an absorption-based semi-high-throughput screening platform (<i>A</i><sub>450</sub>/<i>A</i><sub>600</sub>), we successfully isolated an elite mutant strain, YgM97, that achieved 6.85 mg/L astaxanthin production in shake-flask culture. ...”
  6. 4286

    Multiphoton Luminescence Imaging: A Label-Free Tool for Visualizing the Long-Term Fate of Gold Nanoparticles in Tissue Por Sean Burkitt (21983541)

    Publicado em 2025
    “...We demonstrate that MPL imaging detects up to 98% more AuNP-positive regions than brightfield microscopy in challenging low-dose (1 nM) conditions and requires no modification of standard histology workflows. Correlative imaging with SEM–EDS confirms high spatial specificity (AUC = 0.955) of MPL for AuNP localization. ...”
  7. 4287

    Image 10_Succinylation heterogeneity in lung adenocarcinoma: from prognostic model to KLK6-driven tumor microenvironment remodeling.tif Por Jichang Liu (1263291)

    Publicado em 2025
    “...Protein succinylation, a key post-translational modification, is implicated in tumor progression. However, its comprehensive landscape and clinical significance in LUAD remain largely unexplored....”
  8. 4288

    The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota Por Tobias Tandrup (9312591)

    Publicado em 2025
    “...Despite its abundance, alginate’s heterogeneous composition limits its full utilization. Modification by epimerases and lyases can help to overcome this limitation, but typically requires distinct enzymes for each polysaccharide structure. ...”
  9. 4289

    Table 2_Immunopathology in PMM2-CDG: Defective glycosylation impact in the TNFα -TNFR1 signalling pathway.xlsx Por Carlota Pascoal (6020735)

    Publicado em 2025
    “...Introduction<p>Glycosylation is a post-translational modification that plays a crucial role in immune system activity. ...”
  10. 4290

    Table 1_Adherence to a healthy lifestyle in association with female infertility risk: the mediating role of uric acid.docx Por Zhihui Huang (2541538)

    Publicado em 2025
    “...These findings provide supporting evidence that comprehensive lifestyle modification may be an effective, low-cost strategy for managing infertility....”
  11. 4291

    Table 4_Immunopathology in PMM2-CDG: Defective glycosylation impact in the TNFα -TNFR1 signalling pathway.xlsx Por Carlota Pascoal (6020735)

    Publicado em 2025
    “...Introduction<p>Glycosylation is a post-translational modification that plays a crucial role in immune system activity. ...”
  12. 4292

    Image 9_Succinylation heterogeneity in lung adenocarcinoma: from prognostic model to KLK6-driven tumor microenvironment remodeling.tif Por Jichang Liu (1263291)

    Publicado em 2025
    “...Protein succinylation, a key post-translational modification, is implicated in tumor progression. However, its comprehensive landscape and clinical significance in LUAD remain largely unexplored....”
  13. 4293

    Autophagy dictates PHGDH-mediated serine metabolism in a timely manner to support oocyte development Por Hainan He (12265937)

    Publicado em 2025
    “...At the molecular level, we demonstrated that SAM regulates <i>Igf1</i> expression by altering the H3K4me3 modification level in its promoter region, highlighting a serine-SAM-H3K4me3<i>-Igf1</i> regulatory axis during oocyte maturation. ...”
  14. 4294

    Table 1_Integrated analysis of N-glycosylation and Alzheimer’s disease: identifying key biomarkers and mechanisms.xls Por Hao Zhang (15339)

    Publicado em 2025
    “...N-glycosylation, a critical post-translational modification, is dysregulated in neurodegenerative disorders, yet its role in AD and diagnostic potential remain underexplored....”
  15. 4295

    List of qPCR primer/probes used in the study. Por Ashley P. E. Roberts (4744257)

    Publicado em 2025
    “...While the composition and modification of viral chromatin has been extensively studied on bulk populations of infected cells by chromatin immunoprecipitation, this key regulatory process remains poorly defined at single-genome resolution. ...”
  16. 4296

    Table 1_Early-life undernutrition, immune dysregulation, and cancer incidence in later life: a national life-course analysis from the China health and retirement longitudinal study... Por Hailin Wang (67695)

    Publicado em 2025
    “...Multivariable logistic and Cox mixed-effects models, with interaction terms, quantified dose-response relations and effect modification; estimates from both cohorts were pooled with inverse-variance weighting....”
  17. 4297

    Multiphoton Luminescence Imaging: A Label-Free Tool for Visualizing the Long-Term Fate of Gold Nanoparticles in Tissue Por Sean Burkitt (21983541)

    Publicado em 2025
    “...We demonstrate that MPL imaging detects up to 98% more AuNP-positive regions than brightfield microscopy in challenging low-dose (1 nM) conditions and requires no modification of standard histology workflows. Correlative imaging with SEM–EDS confirms high spatial specificity (AUC = 0.955) of MPL for AuNP localization. ...”
  18. 4298

    Image 8_Succinylation heterogeneity in lung adenocarcinoma: from prognostic model to KLK6-driven tumor microenvironment remodeling.tif Por Jichang Liu (1263291)

    Publicado em 2025
    “...Protein succinylation, a key post-translational modification, is implicated in tumor progression. However, its comprehensive landscape and clinical significance in LUAD remain largely unexplored....”
  19. 4299

    Effect of the number of FNS additions on soil pH. Por Yuanyuan Li (18671)

    Publicado em 2025
    “...The results demonstrated that citric acicd-FeSO<sub>4</sub> significantly enhanced sodium persulfate activation (p < 0.01), achieving within 28 days a 36% higher TPH degradation efficiency than unmodified persulfate at 2% dosage. This modification amplified oxidation intensity and efficiency by up to 2.3-fold over the remediation period.For the contaminated soil with a petroleum hydrocarbon content of 16524 mg/kg, after a 28-day remediation period,FNS amendment achieved significant TPH reductions of 76.9% (to 3820 mg/kg) at 4% dosage-below Class II construction land in China’s soil environmental quality standard (4500 mg/kg). ...”
  20. 4300

    Table 1_Serum small RNA profiling identifies prognostic biomarkers for sepsis mortality prediction.docx Por Yiming Wang (163598)

    Publicado em 2025
    “...Serum samples underwent optimized small RNA profiling using high-throughput sequencing with de-modification protocols to enhance tsRNA and miRNA detection. ...”