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justification » certification (Recherche élargie)
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modifications » modification (Recherche élargie)
codification » modification (Recherche élargie), notification (Recherche élargie), certification (Recherche élargie)
justification » certification (Recherche élargie)
purification » verification (Recherche élargie), publication (Recherche élargie), modification (Recherche élargie)
modifications » modification (Recherche élargie)
codification » modification (Recherche élargie), notification (Recherche élargie), certification (Recherche élargie)
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4321
Image 1_Integrated analysis of N-glycosylation and Alzheimer’s disease: identifying key biomarkers and mechanisms.tif
Publié 2025“…N-glycosylation, a critical post-translational modification, is dysregulated in neurodegenerative disorders, yet its role in AD and diagnostic potential remain underexplored.…”
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4322
Supplementary file 1_Bridging the gap in mental health literacy: co-adapting and feasibility testing a digital intervention to improve mental health literacy amongst young people a...
Publié 2025“…‘Co-adapting’ and ‘co-creating’ refer to collaborative modification and development of intervention content with stakeholders. …”
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4323
Image 5_Succinylation heterogeneity in lung adenocarcinoma: from prognostic model to KLK6-driven tumor microenvironment remodeling.tif
Publié 2025“…Protein succinylation, a key post-translational modification, is implicated in tumor progression. However, its comprehensive landscape and clinical significance in LUAD remain largely unexplored.…”
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4324
Table 3_Succinylation heterogeneity in lung adenocarcinoma: from prognostic model to KLK6-driven tumor microenvironment remodeling.xlsx
Publié 2025“…Protein succinylation, a key post-translational modification, is implicated in tumor progression. However, its comprehensive landscape and clinical significance in LUAD remain largely unexplored.…”
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4325
Data Sheet 1_A study on the correlation between the mean platelet volume to monocyte count ratio and long-term prognosis in patients with newly diagnosed coronary artery disease.xl...
Publié 2025“…Subgroup analyses were performed to test for effect modification. Restricted cubic spline (RCS) models were used to explore the dose–response relationship. …”
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4326
The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota
Publié 2025“…Despite its abundance, alginate’s heterogeneous composition limits its full utilization. Modification by epimerases and lyases can help to overcome this limitation, but typically requires distinct enzymes for each polysaccharide structure. …”
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4327
Supplementary Material for: Demographics, Comorbidity, Treatment, Healthcare Resource Utilization and Costs Analysis of Hidradenitis Suppurativa in Dubai
Publié 2025“…Study population was identified based on International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code L73.2. Patients’ demographics, common comorbidities, treatment patterns, specialty analysis, HCRU, and in patient length of stay were investigated. …”
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4328
Effects of FTO knock-down on THP-1 macrophage immune response induced by <i>T. gondii.</i>
Publié 2025“…<p>A: Changes of m<sup>6</sup>A modification on <i>TNF-α</i> mRNA in FTO knock-down cell lines after <i>T. gondii</i> infection. …”
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4329
Image 1_Succinylation heterogeneity in lung adenocarcinoma: from prognostic model to KLK6-driven tumor microenvironment remodeling.tif
Publié 2025“…Protein succinylation, a key post-translational modification, is implicated in tumor progression. However, its comprehensive landscape and clinical significance in LUAD remain largely unexplored.…”
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4330
Model of the effect of HtrA on GBS perinatal virulence.
Publié 2025“…We also identified human fibronectin (Fn) as a host substrate of GBS HtrA and speculate that proteolytic modification of Fn by GBS HtrA may favor downstream signaling that leads to PTL during WT COH1 infection. …”
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4331
Chemoproteomics Reveals FAM114A2 as a Functional Target of Wikstroelide E for Reversal of HIV‑1 Latency
Publié 2025“…Furthermore, photoreactive probe #2-PP was synthesized through modification of the C<sub>20</sub>–OH of Wikstroelide E with a diazirine alkyne tag for covalent bonding to the target proteins in cells. …”
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4332
Harnessing AEM Electrolyzer-Level Performance through Strategically Designing the Electronic Structure of Electrocatalysts, Enabling Dynamic Functional Switching
Publié 2025“…Detailed studies, including DFT analyses, revealed that electronic structure modification enhances charge delocalization, driving its impressive performance on an industrially significant scale.…”
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4333
Image 7_Succinylation heterogeneity in lung adenocarcinoma: from prognostic model to KLK6-driven tumor microenvironment remodeling.tif
Publié 2025“…Protein succinylation, a key post-translational modification, is implicated in tumor progression. However, its comprehensive landscape and clinical significance in LUAD remain largely unexplored.…”
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4334
Data Sheet 1_From blueprint to practice: an innovative dynamic 9-box grid improves exercise participation and aerobic capacity in graduate students.pdf
Publié 2025“…Weekly feedback demonstrates superior efficacy in sustaining behavior modification and facilitating tier progression. This model provides a replicable, theory-informed strategy for health behavior management in graduate student populations.…”
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4335
Table 2_History of large-for-gestational-age birth is independently associated with subsequent gestational diabetes in Chinese multiparous women: a retrospective cohort study.docx
Publié 2025“…Stratified analyses assessed effect modification by prior GDM, maternal age, and pre-pregnancy BMI in the first pregnancy.…”
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4336
Survey of dysphagia protocol use (Carnaby et al., 2025)
Publié 2025“…Using bolus/texture modification guidelines (i.e., International Dysphagia Diet Standardization Initiative Framework) is uncommon.…”
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4337
Table 1_Multiomics profiling Identifies MCMBP as a prognostic biomarker and a potential immune-related target in pancreatic ductal adenocarcinoma via the JAK–STAT3 pathway.xlsx
Publié 2025“…Low DNA methylation and high m6A modification of MCMBP may promote PAAD progression and correlate with adverse prognosis. …”
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4338
Data Sheet 1_The longitudinal bidirectional association between cardiovascular disease and depressive symptoms among middle-aged and elderly adults: evidence from a nationwide coho...
Publié 2025“…Cross-lagged panel models were performed to evaluate bidirectional associations and strength of temporal relationships simultaneously. Effect modification by demographic and lifestyle factors was also examined to identify vulnerable populations for each directional pathway.…”
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4339
π‑Extended Ru–COUBPY Photosensitizers for <i>In Vivo</i> Anticancer Phototherapy Using One-Photon 780 nm Near-Infrared Light
Publié 2025“…Herein, we report a novel series of ruthenium(II) polypyridyl complexes (<b>Ru4–7</b>) featuring π-extended COUBPY ligands, designed <i>via</i> a vinylogation strategy and synthesized through an innovative postcoordination ligand assembly approach. This structural modification enhances molar absorptivity and red-shifts the absorption bands well into the NIR region without substantially compromising photostability. …”
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4340
Table 1_Zinc deficiency and risk of intracerebral hemorrhage: a retrospective cohort study.docx
Publié 2025“…The ICH association remained consistent across patient subgroups, with no significant effect modification. Multivariate analysis confirmed zinc deficiency as an independent ICH predictor (adjusted HR: 1.87, 95% CI: 1.53–2.29, p < 0.001).…”