Mechanistic basis of phenothiazine‐driven inhibition of Tau aggregation by Akoury, Elias

“…Phenothiazines, such as methylene blue and its azure derivatives, have a unique mechanism, specifically modifying the Tau cysteine residues. The modification keeps Tau in a monomeric disordered conformation preventing the formation of filaments and their toxic precursors.…”
Get full text
Get full text
Get full text
Get full text

Effect of fibre volume on tensile properties of real unidirectional fibre-reinforced composites by Karam, G.N.

“…Based on the reduction of interfacial surfaces due to fibre-fibre interaction, a modification to the rule of mixtures is proposed. The experimentally observed non-linear variation of tensile strength with fibre volume can be predicted by the modified rule. …”
Get full text
Get full text
Get full text
Get full text

"Building Information Modeling (BIM)” Implementation in Construction project and its effects in dispute avoidance and resolution by ALGHAZALI, WESAM M J

“…This research has highlighted the implementation of BIM for the purpose of dispute avoidance. Moreover, the modification in the standard form of contracts and in the legal systems in the process of BIM adoption has also been clearly discussed in this study. …”
Get full text

A Study on the Innovative Business Strategies Adopted by Different Firms in the Construction Industry during the Global Economic Crisis in the U.A.E by Gafoor, Neyas Abdul

“…Various strategic approaches adopted, at the time of recession, by the companies in the construction sector, were studied; the modification of strategies appropriately can maintain or improve their performance in time of crisis.…”
Get full text

Bevacizumab Improves Pathologic Response and Protects Against Hepatic Injury in Patients Treated With Oxaliplatin-Based Chemotherapy for Colorectal Liver Metastases by Ribero, David

“…Bevacizumab-containing regimens significantly reduced the degree of tumor viability compared with 5FU/OX-only chemotherapy (32.9% vs 45.3%; P = .02). After stratification according to the magnitude of tumor viability, a higher proportion of patients treated with bevacizumab than without had <25% residual viable tumor cells (45% vs 23%; P = .02). …”
Get full text
Get full text
Get full text

Suboptimal accuracy of carcinoembryonic antigen in differentiation of mucinous and nonmucinous pancreatic cysts by Azar, Riad R.

“…Future studies should focus on novel cyst fluid markers to improve risk stratification of pancreatic cystic neoplasms.…”
Get full text
Get full text
Get full text
Get full text

Physical drivers of chlorophyll and nutrients variability in the Southern-Central Arabian Gulf by Jassem A. Al-Thani (17337871)

“…Here, using data of chlorophyll, nutrients and hydrographic parameters collected in two cruises in summer 2019 and winter 2020, we examined variability in nutrients and chlorophyll concentrations, and the driving mechanisms. Summer thermal stratification enhanced by intrusion of fresher surface water plume from the Arabian Sea developed a hypoxic zone (DO < 2.0 mL/L) below the thermocline. …”

Refining the Charlson Comorbidity Index for use in long-term care patients by Brijesh Sathian (479264)

“…This context-specific tool improves risk stratification, underscoring the need for tailored prognostic models in Qatar’s evolving healthcare system.…”

An Early Warning Tool for Predicting Mortality Risk of COVID-19 Patients Using Machine Learning by Muhammad E. H. Chowdhury (14150526)

“…The prognostic model, nomogram, and LNLCA score can help in early detection of high mortality risk of COVID-19 patients, which will help doctors to improve the management of patient stratification.</p><h2>Other Information</h2> <p> Published in: Cognitive Computation<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s12559-020-09812-7" target="_blank">http://dx.doi.org/10.1007/s12559-020-09812-7</a></p>…”

Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... by Muhanad Alhujaily (11630107)

“…Spliceosomal proteins were targets of MG modification. Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. …”

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal by Zehra Irshad (18614869)

“…Flux of glucose metabolism, MG formation and glycation and changes in cytosolic protein abundances, MG modification and proteotoxic responses were assessed. …”

Adult appendicitis score versus Alvarado score: A comparative study in the diagnosis of acute appendicitis by Mohamed Said Ghali (16810713)

“…</p><h3>Results</h3><p dir="ltr">AAS risk stratification was applied to the study population. Group I for a low probability, and groups II and III for an intermediate and high probability of AA. …”

Increased complications of COVID-19 in people with cardiovascular disease: Role of the renin–angiotensin-aldosterone system (RAAS) dysregulation by Robin Augustine (3976964)

“…This has impeded adequate risk stratification and treatment strategies for CVD patients with SARS-CoV-2 infections. …”

Network-based identification of key master regulators associated with an immune-silent cancer phenotype by Raghvendra Mall (581171)

“…Defining mechanisms associated with immune evasion is imperative to refine stratification algorithms, to guide treatment decisions and to identify candidates for immune-targeted therapy. …”

A climatological overview of surface currents in the Arabian Gulf with special reference to the Exclusive Economic Zone of Qatar by Afnan Abdirashid Mussa (22504382)

“…The climatological mean current speeds are higher during summer compared to winter, due to the seasonal changes in thickness of the surface layer by the stratification/destratification processes. The highest mean current speeds along the coast of Qatar are found in June and the lowest in winter months. …”

RT-QuIC Using C-Terminally Truncated α-Synuclein Forms Detects Differences in Seeding Propensity of Different Brain Regions from Synucleinopathies by Ilaria Poggiolini (296742)

“…Using recombinant C-αSyn and PD and DLB brain lysates as seeds in the real-time quaking-induced conversion (RT-QuIC) assay, we explored how C-αSyn may be involved in disease stratification. Comparing the seeding activity of aqueous-soluble fractions to detergent-soluble fractions, and using αSyn 1-130 as substrate for the RT-QuIC assay, the temporal cortex seeds differentiated PD and DLB from healthy controls. …”

An EM-Based Forward-Backward Kalman Filter for the Estimation of Time-Variant Channels in OFDM by Al-Naffouri, T.Y.

“…We also suggest a suboptimal modification that is able to track the channel and recover the data with no latency. …”
Get full text
Get full text

Multilayer perceptron-based DFE with lattice structure by Zerguine,, Azzedine

“…The adaptive lattice algorithm is a modification to the one developed by Ling and Proakis (1985). …”

Multilayer perceptron-based DFE with lattice structure by Zerguine, A.

“…The adaptive lattice algorithm is a modification to the one developed by Ling and Proakis (1985). …”
Get full text
Get full text

Incremental & classical genetic algorithm. (c2001) by Awad, Mohamad M.

Get full text
Get full text