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1741
Image 1_Potential antitumoral effects of SRPK1 inhibition through modulation of VEGF splicing in pituitary somatotroph tumoral cells.jpg
منشور في 2025"…SRPK1 is considered a proto-oncogene and its inhibition by small molecule inhibitors SRPIN340 and SPHINX31 have shown antitumoral effects via the SRPK1-SRSF1-VEGF pathway modulation in different cancer types. …"
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1742
COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISEASE
منشور في 2024"…Due to the relatively small size of the FAEs, these are ideal candidates for transport into the brain using GLUT1, SVCT2 and LAT1. …"
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1743
Supplementary file 1_Early life microbiome disbalance impacts neuroendocrine outcomes in pre-pubertal mice in a sexually dimorphic manner.zip
منشور في 2025"…Maternal antibiotics during nursing caused: (1) microbial dysbiosis in the offspring as evident by markedly enlarged ceca, no detectable by-products of bacterial fermentation (sp. SCFA) and dramatic changes in microbial composition, diversity (reduced - alpha Chao1and beta Bray-Curtis, as compared to their respective controls) and predictive metabolic activity; (2) alteration in the transcriptional signature of the adrenal medullae and attenuated peripheral stress responses in male offspring, associated with gap junction signaling pathways; (3) increased anxiety-like testing metrics, and decreased locomotor activity; all in a sexually dimorphic manner.…"
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1744
Scale and environmental data for the analysis of year class growth of coregonids from Lake Starnberg
منشور في 2025"…During the observed period, phosphorus concentrations decreased, indicating reduced nutrient availability, whereas spring temperatures showed no significant long-term trend. …"
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1745
Table 1_Dual variants of uncertain significance in a case of hyper-IgM syndrome: implications for diagnosis and management.docx
منشور في 2025"…Background<p>Hyper-IgM syndrome (HIGM) is a genetic immunodeficiency characterized by elevated to normal IgM levels and decreased IgG, IgA, and IgE. The overlapping clinical presentations of different gene mutations complicate diagnosis and management.…"
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1746
Data Sheet 1_Dual variants of uncertain significance in a case of hyper-IgM syndrome: implications for diagnosis and management.pdf
منشور في 2025"…Background<p>Hyper-IgM syndrome (HIGM) is a genetic immunodeficiency characterized by elevated to normal IgM levels and decreased IgG, IgA, and IgE. The overlapping clinical presentations of different gene mutations complicate diagnosis and management.…"
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1747
Supplementary file 1_Haptic feedback as affective amplifier: enhanced fear perception affects cognitive performance and avoidance actions in VR height exposure.docx
منشور في 2025"…The integration of physiological, behavioral, and subjective measures provides a mechanistic model for affective-motor competition, demonstrating how somatic threat cues translate into altered actions.…"
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1748
Image_1_Prices for veterinary care of dogs, cats and horses in selected countries in Europe.pdf
منشور في 2025"…Additionally, we sought to compare price data from veterinary clinics (ranging from animal hospitals to small private clinics) using a similar approach to VP. …"
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1749
<b>Exploring left lateral decubitus position, and its influence on infant mortality in pregnant women in their third trimester, brought to the emergency through the GVK Ambulance S...
منشور في 2024"…No large studies have been done to adequately understand the immediate and long-term implications of maternal sleep position as a modifiable risk factor, which if addressed may potentially improve infant outcomes like small for gestational babies, stillbirth, and failure-to-thrive. …"
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1750
Table1_Microbe-immune interactions: new perspectives on coagulation deficiencies, purpura, and other hemorrhagic conditions under the regulation of the gut microbiota.xlsx
منشور في 2024"…The mediating effect is opposite to the overall trend and has a relatively small impact. No significant heterogeneity or pleiotropy was observed.…"
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1751
Data Sheet 1_TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury.zip
منشور في 2025"…Spleen tyrosine kinase (SYK) inhibition was achieved using R406, and TREM-1 small interfering RNA (siRNA) and overexpressing plasmids were performed to validate its role in NF-κB signaling and pyroptosis quantified using WB and enzyme-linked immunosorbent assay (ELISA). …"
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1752
Image_1_Prices for veterinary care of dogs, cats and horses in selected countries in Europe.pdf
منشور في 2025"…Additionally, we sought to compare price data from veterinary clinics (ranging from animal hospitals to small private clinics) using a similar approach to VP. …"
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1753
Table2_Microbe-immune interactions: new perspectives on coagulation deficiencies, purpura, and other hemorrhagic conditions under the regulation of the gut microbiota.docx
منشور في 2024"…The mediating effect is opposite to the overall trend and has a relatively small impact. No significant heterogeneity or pleiotropy was observed.…"
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1754
Data Sheet 1_Helminthic larval stage induces cellular apoptosis via caspase 9-mediated mitochondrial dysfunction.pdf
منشور في 2025"…This process is primarily mediated by small molecules (< 30 kDa), and remained unaffected by heat and proteinase treatment. …"
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1755
Data_Sheet_1_Prices for veterinary care of dogs, cats and horses in selected countries in Europe.xlsx
منشور في 2025"…Additionally, we sought to compare price data from veterinary clinics (ranging from animal hospitals to small private clinics) using a similar approach to VP. …"
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1756
Speech sound difficulties, language and reading (Walquist-Sørli et al., 2025)
منشور في 2025"…However, a precision-effect test and the precision-effect estimate with standard errors analysis suggested a potential decrease in effect size due to publication bias from small sample sizes in primary studies.…"
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1757
Data_Sheet_2_Prices for veterinary care of dogs, cats and horses in selected countries in Europe.docx
منشور في 2025"…Additionally, we sought to compare price data from veterinary clinics (ranging from animal hospitals to small private clinics) using a similar approach to VP. …"
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1758
Table3_Microbe-immune interactions: new perspectives on coagulation deficiencies, purpura, and other hemorrhagic conditions under the regulation of the gut microbiota.xlsx
منشور في 2024"…The mediating effect is opposite to the overall trend and has a relatively small impact. No significant heterogeneity or pleiotropy was observed.…"
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1759
Data_Sheet_1_Prices for veterinary care of dogs, cats and horses in selected countries in Europe.xlsx
منشور في 2025"…Additionally, we sought to compare price data from veterinary clinics (ranging from animal hospitals to small private clinics) using a similar approach to VP. …"
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1760
Table_1_Prices for veterinary care of dogs, cats and horses in selected countries in Europe.xlsx
منشور في 2025"…Additionally, we sought to compare price data from veterinary clinics (ranging from animal hospitals to small private clinics) using a similar approach to VP. …"