Table 2_Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model.docx por M. N. Rossi (22100030)

“…Recent studies suggest that epigenetic modifications, particularly DNA methylation (DNAm), play a critical role in the development of chronic kidney disease. …”

Data Sheet 1_Fasting elicits gut microbiome signature changes that extend to type 1 diabetes patients.docx por Franziska A. Graef (11237282)

“…A correlation analysis between fasting-mediated microbiota modifications and changes in clinical parameters revealed several significant associations between the Oscillospiraceae and Lachnospiraceae families and cholesterol and blood pressure changes in the T1D cohort, corroborating previous studies reporting on these associations in non-diabetic subjects. …”

Image 2_Construction of a glycosylation-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in soft tissue sarcoma.jpeg por Ningning Yuan (4231858)

“…Background<p>Altered glycosylation, one of the most common post-translational protein modifications, plays a critical role in the initiation and progression of soft tissue sarcoma (STS). …”

Table 2_Multi-omics integration to identify immune-associated biomarkers and potential therapeutics in periodontitis.xlsx por Ling Jin (133762)

“…Background<p>Periodontitis, a chronic inflammatory disease of periodontal tissues, is linked to immune response and epigenetic modifications, with DNA methylation playing a crucial role. …”

Data Sheet 1_Case Report: Solitary adrenal metastasis from esophageal adenocarcinoma.pdf por Riddhi Machchhar (21731564)

“…The patient then began a new chemotherapy regimen with Taxol/Ramucirumab with dose modifications in response to side effects. Continued adjustments to the treatment and dosages were made for progressive side effects and the patient elected to receive palliative radiation to the esophagus, along with holistic supportive care. …”

Concentration-Specific Neurotoxic Pathways of Tetrabromobisphenol A and Tetrabromobisphenol A Bis(2-Hydroxyethyl Ether) in Zebrafish Larvae por Hai Xu (141126)

“…In contrast, exposure to environmentally relevant concentrations induced similar phenotypes (craniofacial malformations and apoptosis) without major changes in neurotransmitter levels, suggesting that low-dose neurotoxicity might be mediated by alternative, less understood mechanisms, possibly involving epigenetic modifications or compensatory neuronal adaptations. These findings underscore the complexity of low-dose toxicity and the need for further research into the molecular pathways underlying the neurotoxic effects of TBBPA and its derivatives, particularly at environmentally relevant concentrations.…”

Image 1_Association between the serum albumin-to-creatinine ratio and 28-day all-cause mortality in sepsis: a retrospective cohort study.jpeg por Kerui Wu (10329647)

“…Explored the relationship between ACR and 28-day all-cause mortality using Cox proportional risk regression and Kaplan–Meier survival curves, and conducted subgroup analysis to evaluate the effect modifications across different patient populations. Applied the restricted cubic spline (RCS) curves to assess the nonlinear relationships, and the receiver operating characteristic (ROC) curve to assess the predictive performance.…”

Enhanced Adsorption and Enzymatic Hydrolysis of Polyethylene Terephthalate by Cutinase with an N‑Terminal Hydrophobic Tether por Md Sadikur Rahman Shuvo (22374895)

“…The enzyme kinetic parameters of both conjugated and unconjugated cutinases revealed that the modifications have a minimal impact on catalytic activity. …”

Table 3_Association between the serum albumin-to-creatinine ratio and 28-day all-cause mortality in sepsis: a retrospective cohort study.docx por Kerui Wu (10329647)

“…Explored the relationship between ACR and 28-day all-cause mortality using Cox proportional risk regression and Kaplan–Meier survival curves, and conducted subgroup analysis to evaluate the effect modifications across different patient populations. Applied the restricted cubic spline (RCS) curves to assess the nonlinear relationships, and the receiver operating characteristic (ROC) curve to assess the predictive performance.…”

Multiscale Modeling of Phosphorene-Based Sensing Devices for Volatile Organic Compounds por Calin-Andrei Pantis-Simut (22071037)

“…In this way, we account for the electronic structure modifications induced in the active layer by the attached biomarkers with different configurations, which are extracted from ab initio molecular dynamics simulations. …”

Supplementary file 1_Meta-analysis of mesenchymal stem cell therapy for intrauterine adhesions: a comprehensive consideration of efficacy and safety.docx por Jiawei Gao (11758514)

“…</p>Trial registration<p>The review protocol is registered on PROSPERO with registration number CRD42025643871, and no modifications were made to the information provided at registration.…”

Image 1_EEG-based characterization of auditory attention and meditation: an ERP and machine learning approach.png por Eyad Talal Attar (22124251)

“…The research findings deliver strong evidence that meditation induces distinct neural modifications detectable through ERP and spectral analysis. …”

Environmental Census: Modeling Synthetic Biology Ecological Risk with Metagenomic Enzymatic Data and High-Performance Computing por John Docter (22772100)

“…When further utilizing <i>EnCen</i> to investigate the receiving environments comprising the central database, key enzyme classes are mapped as characteristics to select environments, prioritizing certain modifications likely leading to a greater risk (or effectiveness) of establishment. …”

Supplementary file 2_Evaluation of the effects of clearing agents, fixation, and process durations on cardiovascular tissue imaging with second harmonic generation and multi-photon... por Maedeh Makki (21785114)

“…However, significant modifications are required for clearing different tissue types. …”

Systems biology and functional assessments of human iPSC-cardiomyocyte models of insulin resistance captures key hallmarks of diabetic cardiomyopathy por Ryan D. Carter (22055295)

“…However, 3D EHT provide additional insights into physiological and structural modifications. This highlights the potential of IR EHT for both mechanistic studies and drug screening in DbCM.…”

Table 3_A scoping review on the impact of versatile Digital Health innovations on pharmacy education.docx por Fahad T. Alsulami (19929083)

“…However, faculty development, curriculum gaps, workload integration, insufficient telehealth training, regional disparities, and inadequate AI ethics instruction all point to the need for adequate and relevant curriculum modifications to qualify graduates to deal with Digital healthcare challenges.…”

Image 8_EEG-based characterization of auditory attention and meditation: an ERP and machine learning approach.png por Eyad Talal Attar (22124251)

“…The research findings deliver strong evidence that meditation induces distinct neural modifications detectable through ERP and spectral analysis. …”

A Robust Hybrid Skeleton for Omnidirectional Underwater Bubble Collection por Lei Dong (165252)

“…This study provides a practical solution for underwater bubble collection, overcoming the constraints of surface-only modifications and the material limitations of polymers and metals prevalent in current research.…”

A Robust Hybrid Skeleton for Omnidirectional Underwater Bubble Collection por Lei Dong (165252)

“…This study provides a practical solution for underwater bubble collection, overcoming the constraints of surface-only modifications and the material limitations of polymers and metals prevalent in current research.…”

Figure 1 from INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors por Catherine Dietrich (18084160)

“…<b>B,</b> Derivation of INX-315 through serial modifications of trilaciclib, a CDK4/6i. Table indicates biochemical IC₅₀s (± SEM) to cyclin/CDK pairings shown using the Nanosyn biochemical assay. …”