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Improved Pharmacokinetic Profiles of HDAC6 Inhibitors via Cap Group Modifications
Publicado 2025“…Hydroxamic acid (HA)-based HDAC inhibitors often suffer from poor pharmacokinetic (PK) profiles, limiting their in vivo applications. Cap group modification offers a promising strategy to address these challenges. …”
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Research Progress on Histone Lactylation Modification in Ischemic Stroke: Mechanisms and Therapeutic Potential
Publicado 2025Materias: “…Histone lactylation modification…”
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<b>Lossless Altered Histone Modification Analysis System (LAHMAS)</b>m
Publicado 2025“…The resultant Lossless Altered Histone Modification Analysis System (LAHMAS) employs a PDMS-silane treated glass surface immersed in silicone oil to facilitate lossless liquid handling and prevent sample evaporation. …”
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Modification map illustrating the three-point force system for correcting pronation of the foot.
Publicado 2025Materias: -
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Summary of Substituted Cysteine Modification and Anesthetic Protection Studies in α1 Subunits.
Publicado 2025Materias: “…substituted cysteine modification…”
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Summary of Substituted Cysteine Modification and Anesthetic Protection Studies in β3 Subunits.
Publicado 2025Materias: “…substituted cysteine modification…”
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Characteristics of the interventions: tailoring, modification, how well (planned) and how well (actual).
Publicado 2025“…<p>Characteristics of the interventions: tailoring, modification, how well (planned) and how well (actual).…”
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Impact of RNA modification gene deletions on fitness during growth in sub-MIC tobramycin.
Publicado 2025Materias: -
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Table 2_Survival strategies of mycoplasmas: the critical role of post-translational modifications.docx
Publicado 2025Materias: “…post-translational modifications…”
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Model-inferred target product parameter values for population modification gene drive systems.
Publicado 2025“…<p>Model-inferred target product parameter values for population modification gene drive systems.</p>…”
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Summary of Substituted Cysteine Modification and Anesthetic Protection Studies in γ2L Subunits.
Publicado 2025Materias: “…substituted cysteine modification…”
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Additional file 3 of Exploring modifications to rapid response systems in Norwegian hospital units
Publicado 2025Materias: -
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Pharmacologic modification of the tumor microenvironment reduces astrogliosis and harmonizes astrocytic GLT1 expression.
Publicado 2025Materias: “…pharmacologically induced modification…”
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