Table 7_Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2.xlsx od Vineetha Shaji (21626417)

“…</p>Discussion and Conclusions<p>This study presents a framework for predicting human kinases of specific SARS-CoV-2 protein phosphosites by integrating kinase specificity, virus–host interactions, and post-translational modifications. MAP2K1 was identified as a key host kinase, showing stronger interactions than SRPK1, and is proposed as an antiviral drug target for repurposing in SARS-CoV-2 infections.…”

Table 5_Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2.xlsx od Vineetha Shaji (21626417)

“…</p>Discussion and Conclusions<p>This study presents a framework for predicting human kinases of specific SARS-CoV-2 protein phosphosites by integrating kinase specificity, virus–host interactions, and post-translational modifications. MAP2K1 was identified as a key host kinase, showing stronger interactions than SRPK1, and is proposed as an antiviral drug target for repurposing in SARS-CoV-2 infections.…”

Table 1_Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration.xlsx od Chencheng Zhang (6877691)

“…</p>Conclusion<p>This study establishes a visceral pain model centered on pancreatic parenchymal nociception rather than secondary neural effects, and for the first time proposes an interconnected regulatory network linking epigenetic modifications, immune reprogramming, and neural plasticity, revealing dual pain pathogenesis mechanisms: (1) immune microenvironment reshaping that potentiates neuroinflammation, and (2) direct ion channel regulation enhancing neuronal excitability. …”

Table 4_Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2.xlsx od Vineetha Shaji (21626417)

“…</p>Discussion and Conclusions<p>This study presents a framework for predicting human kinases of specific SARS-CoV-2 protein phosphosites by integrating kinase specificity, virus–host interactions, and post-translational modifications. MAP2K1 was identified as a key host kinase, showing stronger interactions than SRPK1, and is proposed as an antiviral drug target for repurposing in SARS-CoV-2 infections.…”

Image 1_Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2.tif od Vineetha Shaji (21626417)

“…</p>Discussion and Conclusions<p>This study presents a framework for predicting human kinases of specific SARS-CoV-2 protein phosphosites by integrating kinase specificity, virus–host interactions, and post-translational modifications. MAP2K1 was identified as a key host kinase, showing stronger interactions than SRPK1, and is proposed as an antiviral drug target for repurposing in SARS-CoV-2 infections.…”

Data Sheet 2_Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration.zip od Chencheng Zhang (6877691)

“…</p>Conclusion<p>This study establishes a visceral pain model centered on pancreatic parenchymal nociception rather than secondary neural effects, and for the first time proposes an interconnected regulatory network linking epigenetic modifications, immune reprogramming, and neural plasticity, revealing dual pain pathogenesis mechanisms: (1) immune microenvironment reshaping that potentiates neuroinflammation, and (2) direct ion channel regulation enhancing neuronal excitability. …”

m⁶A‑Methylated Taurine Transporter SLC6A6 Promotes Arsenic-Induced Malignant Transformation of Keratinocytes while Enhancing Sensitivity to Cuproptosis od Tianhe Zhao (21727376)

“…Furthermore, <i>N</i>⁶-methyladenosine (m⁶A) methyltransferase METTL3 catalyzed m⁶A modifications at multiple sites on SLC6A6 mRNA, promoting the stability and translation of SLC6A6 mRNA by recruiting m⁶A binding protein YTHDF1 during arsenite-induced transformation. …”

Data Sheet 1_Integrated modelling of shading effects on alfalfa growth across different agrivoltaic systems.docx od Michele Moretta (22534187)

“…In particular, yield differences among treatments reflected microclimatic modifications induced by the panels, with shading and rainfall redistribution likely affecting canopy temperature, soil moisture dynamics, and associated plant water relations. …”

Video 1_Real-time segmentation and phenotypic analysis of rice seeds using YOLOv11-LA and RiceLCNN.mp4 od Dejia Zhang (18526510)

“…YOLOv11-LA incorporates several enhancements over YOLOv11, including separable convolutions, CBAM (Convolutional Block Attention Module) attention mechanisms, and module pruning strategies. These modifications not only improve detection accuracy but also significantly reduce the number of parameters by 63.2% and decrease computational complexity by 51.6%. …”

Data Sheet 1_From counsel to consumption: examining sociocultural influences on perinatal nutrition in rural India.docx od Faiz A. Hashmi (21772319)

“…Interventions must leverage culturally endorsed foods while promoting incremental modifications to restrictive practices. Educational interventions show promise, given the gradient effect of education on dietary practices. …”

Data Sheet 1_Serum levels of per- and polyfluoroalkylated substances and methylation of DNA from peripheral blood.pdf od Hanane Omichessan (4991552)

“…Previous research, which has primarily centered on global methylation patterns, has suggested that some effects of PFAS on human health may be linked to modifications in DNA methylation (DNAm). The aim of our study was to assess the relationship between the serum levels of PFOS and PFOA and CpG site-specific methylation of DNA from peripheral blood.…”

The dataset used to build images in this article. od Junda Zhu (7991426)

“…Using structure-guided mutagenesis and phosphoproteomics, we identified two critical phosphorylation sites within the IDR, S127 and S130, which are essential for the interaction between H5 and DNA. These modifications are mediated redundantly by host proteins and viral B1 kinases. …”

Table 1_Normal adrenocorticotropic hormone levels do not exclude adrenal insufficiency during immune checkpoint inhibitor therapy: evidence from clinical, steroid, and structural a... od Yuria Ishibashi (22459657)

“…Gel filtration chromatography identified high-molecular-weight ACTH forms in the preserved group, suggesting altered proopiomelanocortin processing or post-translational modifications that impaired ACTH bioactivity.</p>Conclusions<p>Adrenal insufficiency may occur when plasma ACTH levels remain within or above the normal range. …”

Data Sheet 2_From counsel to consumption: examining sociocultural influences on perinatal nutrition in rural India.docx od Faiz A. Hashmi (21772319)

“…Interventions must leverage culturally endorsed foods while promoting incremental modifications to restrictive practices. Educational interventions show promise, given the gradient effect of education on dietary practices. …”

Data Sheet 1_High-intensity interval training versus moderate-intensity continuous training for polycystic ovary syndrome: a meta-analysis of randomized controlled trials.pdf od Yi Zhao (14034)

“…Objective<p>Polycystic Ovary Syndrome (PCOS) is the most prevalent endocrine disorder affecting women of reproductive age. Lifestyle modifications, particularly exercise, are cornerstone management strategies, with High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) being commonly recommended modalities. …”

Display the effects of (a) pitch [ od Kayab Khandakar (20933911)

“…Refractive index changes in PCF are usually the cause of action for PCF-based biosensors. These modifications have an impact on how light travels within the fiber. …”

Table 1_Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2.xlsx od Vineetha Shaji (21626417)

“…</p>Discussion and Conclusions<p>This study presents a framework for predicting human kinases of specific SARS-CoV-2 protein phosphosites by integrating kinase specificity, virus–host interactions, and post-translational modifications. MAP2K1 was identified as a key host kinase, showing stronger interactions than SRPK1, and is proposed as an antiviral drug target for repurposing in SARS-CoV-2 infections.…”

Data Sheet 1_Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration.zip od Chencheng Zhang (6877691)

“…</p>Conclusion<p>This study establishes a visceral pain model centered on pancreatic parenchymal nociception rather than secondary neural effects, and for the first time proposes an interconnected regulatory network linking epigenetic modifications, immune reprogramming, and neural plasticity, revealing dual pain pathogenesis mechanisms: (1) immune microenvironment reshaping that potentiates neuroinflammation, and (2) direct ion channel regulation enhancing neuronal excitability. …”

Supplementary file 1_Metabolomic profiling of indigenous lactic acid bacteria reveals functional traits shaping the flavor and bioactivity of Ecuadorian coffee.docx od Victor Cifuentes (396475)

“…Functional group analysis via attenuated total reflectance Fourier transforms infrared (ATR-FTIR) spectroscopy provided insights into structural and biochemical changes, including protein, carbohydrate, and lipid modifications during LAB activity. Total polyphenol content (TPC) and total flavonoid content (TFC) were quantified to assess nutritional and antioxidant shifts.…”

Table 4_Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration.xlsx od Chencheng Zhang (6877691)

“…</p>Conclusion<p>This study establishes a visceral pain model centered on pancreatic parenchymal nociception rather than secondary neural effects, and for the first time proposes an interconnected regulatory network linking epigenetic modifications, immune reprogramming, and neural plasticity, revealing dual pain pathogenesis mechanisms: (1) immune microenvironment reshaping that potentiates neuroinflammation, and (2) direct ion channel regulation enhancing neuronal excitability. …”