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justifications » justification (Espandi la ricerca)
purification » publication (Espandi la ricerca)
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5561
Table 2_High-dose medium-term HMB supplementation did not trigger body composition changes in trained and untrained males under usual conditions or high-intensity functional exerci...
Pubblicazione 2025“...</p>Discussion<p>The individually adjusted high HMB dose did not change body mass and composition in trained or untrained individuals during a three-week exclusive supplementation or three-week supplementation in combination with additional HIFT stimuli. Therefore, any modifications in this area may likely require a longer treatment period....”
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5562
Table 2_Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2.xlsx
Pubblicazione 2025“...</p>Discussion and Conclusions<p>This study presents a framework for predicting human kinases of specific SARS-CoV-2 protein phosphosites by integrating kinase specificity, virus–host interactions, and post-translational modifications. MAP2K1 was identified as a key host kinase, showing stronger interactions than SRPK1, and is proposed as an antiviral drug target for repurposing in SARS-CoV-2 infections....”
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5563
Precise Modulation of Donor–Acceptor Spatial Configuration and Excited-State Energy Alignment for Efficient Red-Shifted TADF Emitters
Pubblicazione 2025“...A series of emitters (<b>6(7)-PXZ-FQ</b> and <b>6(7)-MeODPA-FQ</b>) were designed, wherein <b>6-PXZ-FQ</b> and <b>6-MeODPA-FQ</b> achieved emission peaks at 654 and 618 nm, respectively, demonstrating significant bandgap narrowing via D–A distance compression. Structural modifications concurrently enhanced ICT strength and transition dipole moments, inducing red-shifted emission while maintaining high photoluminescence quantum yields. ...”
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5564
Supplementary file 1_Development and Validation of an Indian Nutrition and Food Literacy Tool (INFOLIT) for adolescents.docx
Pubblicazione 2025“...</p>Conclusion<p>The INFOLIT is a validated and culturally relevant tool for assessing adolescent NFL and can be adapted for use in various Indian regions and contexts after minor modifications.</p>...”
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5565
Data Sheet 3_From counsel to consumption: examining sociocultural influences on perinatal nutrition in rural India.docx
Pubblicazione 2025“...Interventions must leverage culturally endorsed foods while promoting incremental modifications to restrictive practices. Educational interventions show promise, given the gradient effect of education on dietary practices. ...”
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5566
Display the effects of (a) pitch [
Pubblicazione 2025“...Refractive index changes in PCF are usually the cause of action for PCF-based biosensors. These modifications have an impact on how light travels within the fiber. ...”
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5567
Precise Modulation of Donor–Acceptor Spatial Configuration and Excited-State Energy Alignment for Efficient Red-Shifted TADF Emitters
Pubblicazione 2025“...A series of emitters (<b>6(7)-PXZ-FQ</b> and <b>6(7)-MeODPA-FQ</b>) were designed, wherein <b>6-PXZ-FQ</b> and <b>6-MeODPA-FQ</b> achieved emission peaks at 654 and 618 nm, respectively, demonstrating significant bandgap narrowing via D–A distance compression. Structural modifications concurrently enhanced ICT strength and transition dipole moments, inducing red-shifted emission while maintaining high photoluminescence quantum yields. ...”
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5568
Table 5_Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration.xlsx
Pubblicazione 2025“...</p>Conclusion<p>This study establishes a visceral pain model centered on pancreatic parenchymal nociception rather than secondary neural effects, and for the first time proposes an interconnected regulatory network linking epigenetic modifications, immune reprogramming, and neural plasticity, revealing dual pain pathogenesis mechanisms: (1) immune microenvironment reshaping that potentiates neuroinflammation, and (2) direct ion channel regulation enhancing neuronal excitability. ...”
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5569
Data Sheet 1_Dietary supplementation with a designer metabolic modulator improves MASLD and associated anxiety in mice.pdf
Pubblicazione 2025“...The therapeutic approach for MASLD relies on weight management through dietary and behavioral modifications. Nutritional interventions with essential amino acids (EAAs) have emerged as safe and promising tools in treating metabolic disorders and liver diseases. ...”
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5570
Supplementary file 1_Functional deletion of α7 nicotinic acetylcholine receptor impairs Ca2+-dependent glutamatergic synaptic transmission by affecting both presynaptic and postsyn...
Pubblicazione 2025“...From a molecular point of view, hippocampal neurons of α7-KO mice exhibited an increased expression of the pre-synaptic protein Synapsin-1 and of the NMDA subunits GluN2A and GluN2B, but no modifications in the expression of AMPA receptor subunits (GluA1 and GluA2) were found. ...”
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5571
Video 2_Real-time segmentation and phenotypic analysis of rice seeds using YOLOv11-LA and RiceLCNN.mp4
Pubblicazione 2025“...YOLOv11-LA incorporates several enhancements over YOLOv11, including separable convolutions, CBAM (Convolutional Block Attention Module) attention mechanisms, and module pruning strategies. These modifications not only improve detection accuracy but also significantly reduce the number of parameters by 63.2% and decrease computational complexity by 51.6%. ...”
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5572
Supplementary file 1_Design and validation of a mixed reality workflow for structural cardiac procedures in interventional cardiology.docx
Pubblicazione 2025“...</p>Methods<p>The system was built using Unity with modifications to the UnityVolumeRendering plugin for Digital Imaging and Communications in Medicine (DICOM) data processing and volume rendering, Mixed Reality Toolkit (MRTK) for user interactions, and Photon Unity Networking (PUN2) for multi-user synchronization. ...”
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5573
Anonymized Raw Data.
Pubblicazione 2025“...Conversely, the odds of enrolling MSM were highest at selected health facilities. Modifications to the sampling approach were introduced in Kenge and Goma, but these did not affect the enrollment of MSM or SW participants. ...”
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5574
CDK6 271123 6Plex TMT.csv
Pubblicazione 2025“...Search criteria included oxidation of methionine (+15.995Da), acetylation of the protein N-terminus (+42.011Da) and Methionine loss plus acetylation of the protein N-terminus (-89.03Da) as variable modifications and carbamidomethylation of cysteine (+57.0214) and the addition of the TMTpro mass tag (+304.207) to peptide N-termini and lysine as fixed modifications....”
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5575
Data Sheet 1_Inflammatory markers partially mediate the association between volatile organic compounds exposure and hyperlipidemia: a nationally representative cross-sectional stud...
Pubblicazione 2025“...Subgroup analyses assessed effect modifications by sex and age. Multiple-mediator analysis examined the roles of inflammatory biomarkers (white blood cell, lymphocyte, and neutrophil counts) in the association between VOC exposure and hyperlipidemia....”
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5576
Image 1_Impact of long-acting glucocorticoids on ICU mortality in septic patients with acute respiratory failure: a MIMIC-IV based cohort study.jpeg
Pubblicazione 2025“...Additionally, a multivariable Cox proportional hazards regression model was employed to adjust for illness severity and treatment-related covariates, with further exploratory subgroup analyses performed to assess potential effect modifications.</p>Results<p>This study analyzed a cohort of 10,707 patients diagnosed in Septic Patients with Acute Respiratory Failure, among whom 2,298 (21.5%) succumbed to ICU mortality. ...”
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5577
Supplementary file 1_Biodegradation potential of Gordonia spp. on polypropylene and polystyrene: enhanced degradation through pretreatment.docx
Pubblicazione 2025“...</p>Results<p>Notably, Gordonia polyisoprenivorans B253 demonstrated remarkable degradation capabilities, as evidenced by: (1) characteristic chemical modifications including hydroxyl group formation (3,280 cm<sup>−1</sup>), carbon-carbon double bond generation (1,640 cm<sup>−1</sup>), and ether group appearance (1,100 cm<sup>−1</sup>) in ATR-FTIR spectra; (2) pronounced surface erosion patterns observed via SEM; and (3) significant mass reduction (1.927% ± 0.038% of PS) compared to controls. ...”
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5578
Baseline characteristics of study participants.
Pubblicazione 2025“...</p><p>Conclusions</p><p>The escalating prevalence of MetS in the elderly is a matter of increasing concern, underscoring the need for targeted policy interventions aimed at promoting healthy aging, empowering the elderly, and advocating for lifestyle modifications.</p></div>...”
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5579
Table 1_Role of histone-lysine N-methyltransferase 2D (KMT2D) in MEK-ERK signaling-mediated epigenetic regulation: a phosphoproteomics perspective.xlsx
Pubblicazione 2025“...Among these, post-translational modifications, especially phosphorylation, serve as an essential regulator, fine-tuning KMT2D stability, localization and functional interactions for maintaining cellular homeostasis. ...”
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5580
Data Sheet 1_The traditional Chinese medicine manipulation combined with Schroth exercises for adolescent idiopathic scoliosis: protocol for a randomized controlled trial.docx
Pubblicazione 2025“...ITMCTR2025000131). Any important modifications to the protocol will be submitted for approval by the institutional ethics committee and updated in the ITMCTR....”