Comprehensive representation of the training process for paired stain synthesis and computation of loss functions H&E ↔ stain <i>i.</i> per Mehdi Ounissi (22470332)

“…Each panel illustrates the modifications of the model aimed at enhancing the precision and consistency of stain synthesis and discrimination in paired training scenarios.…”

Schematic of the silkworm larva (B100rw) hydrogel preparation. per Maki Yamazaki (12464688)

“…This schematic diagram is adapted from a previous study [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0335864#pone.0335864.ref007" target="_blank">7</a>] with some modifications.</p>…”

<i><b>N</b></i>‑Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral Activity per Anirban Ghoshal (4338757)

“…Structure–activity studies revealed modifications that improve metabolic stability while retaining antiviral activity. …”

Improving Urban Climate Adaptation Modeling in the Community Earth System Model (CESM) Through Transient Urban Surface Albedo Representation per Yuan Sun (17888210)

“…Results highlight the cooling effects of roof albedo modifications, which reduce the annual-mean canopy urban heat island intensity from 0.8°C in 2015 to 0.2°C by 2099. …”

Table 2_Histone-related gene WDR77 promotes tumor progression through cell cycle regulation in skin cutaneous melanoma.xls per Haoxue Zhang (12208580)

“…Epigenetic dysregulation, particularly histone modifications, contributes to disease progression. However, effective histone-based prognostic biomarkers are still lacking in clinical practice.…”

UUATAC Data per Camille Myers (17379841)

“…</p><p dir="ltr"><b>CUTTag_data.tar:</b> CUT&Tag sequencing data for murine adrenal and pituitary glands, profiling histone modifications (H3K4me1, H3K4me3, H3K27ac) and the transcription factor CTCF.…”

Table 2_Multidimensional analysis suggests that ZNF433 is a promising biomarker for the diagnosis and prognosis of human cancers.xlsx per Lingyu Xie (21596492)

“…Background<p>Zinc finger proteins, particularly members of the Krüppel-associated box zinc finger proteins (KRAB-ZFPs), play critical roles in regulating gene expression, cell cycle progression, and epigenetic modifications. Despite the growing body of research on KRAB-ZFPs, the role of ZNF433, a relatively less studied member of this family, remains poorly understood in the context of cancer.…”

Data Sheet 1_Effects of meteorological factors on outpatient visits for chronic rhinosinusitis in Wuhan, China (2018–2019): a time-series analysis.docx per Xiaoli Guan (9723784)

“…Stratified analyses were conducted to identify potential effect modifications by age and season.</p>Results<p>A total of 14,259 CRS outpatient visits were recorded. …”

Data Sheet 1_Potential use of repetitive transcranial magnetic stimulation in treating pediatric avoidant/restrictive food intake disorder: a case report.pdf per Ru Wang (282586)

“…Currently, the management of ARFID is multidisciplinary, involving dietary modifications, pharmacological treatments, and psychotherapy, but no standardized treatment protocol exists. …”

Fusion transcripts landscape in hepatocellular carcinoma and potential impact on the expression of fusion partners per Yasemin Öztemur Islakoğlu (21686283)

“…Detailed characterization of SERPINA1-H19 identified 16 transcript variants with distinct structural modifications that may impact its functional output. …”

Table 1_The role of teachers in the prevention and management of childhood obesity among school-aged children in Ghana: a cross-sectional study.docx per Chantal Kayitesi (22768781)

“…</p>Conclusion<p>The results highlight the necessity for specific measures, including professional development initiatives, institutional policy modifications, and resource distribution, to improve teachers’ ability to combat childhood obesity. …”

Image 1_Functional characterization and clinical significance of IGSF8 in pan-cancer: an integrated bioinformatic and experimental study.tif per Jie Wang (16762)

“…IGSF8 was also closely associated with multiple indicators of tumor heterogeneity, stemness, as well as significant RNA methylation modifications across various cancers. Drug sensitivity analysis identified BX-795 and tozasertib as potential treatments for tumors with high IGSF8 expression. …”

Exploring the impact of serine phosphorylation flanking the KxGS motif in the repeat 3 domain of human tau on tubulin detachment per Selvaa Kumar C. (20504321)

“…Post-translational modifications, such as the phosphorylation of serine residues within these repeat domains, regulate the tau protein’s association and dissociation with tubulin protein. …”

Image 2_Multi-omics integration to identify immune-associated biomarkers and potential therapeutics in periodontitis.tif per Ling Jin (133762)

“…Background<p>Periodontitis, a chronic inflammatory disease of periodontal tissues, is linked to immune response and epigenetic modifications, with DNA methylation playing a crucial role. …”

Data Sheet 2_Establishment of a CT-based radiomic feature robustness databank for OPC patients via image perturbation in a multi-institutional study: a practical method to safeguar... per Yongqiang Wang (211682)

“…The original images and corresponding masks underwent systematic perturbations to simulate potential variations encountered during CT image rescanning, including translational shifts, rotational changes, random noise additions, and contour modifications. For each radiomic feature (RF), including unfiltered, wavelet-filtered, and Laplacian-of-Gaussian (LoG)-filtered features, we systematically quantified robustness against these perturbations by intraclass correlation coefficients (ICCs).…”

Table 1_Gender differences in the association between smoking and the risk of suicide in depressed patients: a longitudinal national cohort study.docx per Yoo Jin Jang (22465372)

“…Subgroup analyses explored effect modifications by covariates, including age, income, and alcohol use.…”

Image 7_Pan-cancer analysis reveals ELFN1 as a novel prognostic biomarker and immunotherapeutic target associated with tumor microenvironment remodeling and promoting malignant phe... per Sha-Sha Hu (6417878)

“…</p>Methods<p>Through integrative analysis of TCGA and GTEx datasets, we systematically characterized ELFN1 across 33 cancer types, including its expression patterns, prognostic value, mutation landscape, methylation modifications, protein-protein interaction (PPI) networks, and the relationship between ELFN1 expression and immune infiltration. …”

Table 1_Construction of a glycosylation-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in soft tissue sarcoma.docx per Ningning Yuan (4231858)

“…Background<p>Altered glycosylation, one of the most common post-translational protein modifications, plays a critical role in the initiation and progression of soft tissue sarcoma (STS). …”

Construct validity, internal consistency and test-retest reliability of the Swedish version of the Hearing and Functioning in Everyday Life Questionnaire (HFEQ) per Elin Karlsson (500465)

“…</p> <p>With some modifications of the original HFEQ structure, a CFA showed sufficient model fit and confirmed the HFEQ construct. …”

Data Sheet 1_Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model.pdf per M. N. Rossi (22100030)

“…Recent studies suggest that epigenetic modifications, particularly DNA methylation (DNAm), play a critical role in the development of chronic kidney disease. …”