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latest decrease » largest decrease (Expand Search), greatest decrease (Expand Search), largest decreases (Expand Search)
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FOXO1-mediated Downregulation of RAB27B Leads to Decreased Exosome Secretion in Diabetic Kidneys
Published 2021“…Overexpression of RAB27B restored exosome secretion in HG-treated cells, suggesting a role of RAB27B downregulation in the decrease of exosome secretion in DKD. …”
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The effect of tensile feedback on constrictions in a disrupted zone with decreased constriction probability.
Published 2021“…<p>(<b>A,B</b>) Simulation snapshots for the AGF model with a band of cells whose constriction probability is decreased by the factor <i>α</i><sub>r</sub> = 0.6 (top) 0.4 (middle) and 0.2 (bottom) relative to the probability outside the affected zone. …”
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<b>The loss of insulin-positive cell clusters precedes the decrease of islet frequency and beta cell area in type 1 diabetes</b>
Published 2025“…Insulin-positive (INS+) single cells (≤10µm), cell clusters (>10 to <35µm), small- and medium-sized islets (35-100µm and 100-200µm) were significantly lost at type 1 diabetes onset, while large INS+ islets (>200µm) were preserved. Moreover, changes in endocrine composition also occurred in mAAb+ donors, including a significant decrease in the INS+ islet fraction. …”
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