Image 1_A case report: enhanced somatostatin receptor expression in metastatic pancreatic neuroendocrine tumor following everolimus therapy.pdf by Pei Zhang (232846)

“…In January 2024, everolimus therapy was started, resulting in a partial response by April 2024, with a significant reduction in liver metastases. Due to small intestinal ulcers, the dose of everolimus was reduced in August 2024. …”

Flow cytometric identification of dynamic immune cell populations in a rat model of post-traumatic elbow contracture by Rebecca F. Reals (22770489)

“…Previous findings implied immune system activation in capsules of contracted joints; however, quantifying immune cell populations in rodent joint tissues is challenging due to small size and low cellularity. Here, we used flow cytometry to investigate the temporal immune response and enumerate cell populations in the rat elbow capsule after traumatic injury.…”

Table 1_The real-world safety of Nivolumab: a pharmacovigilance analysis based on the FDA adverse event reporting system.docx by Yutong Wu (3130584)

“…The most frequently reported AEs included fatigue, dyspnea, musculoskeletal pain, decreased appetite, cough, nausea, and constipation. …”

Rinderine suppresses African swine fever virus replication in porcine alveolar macrophages by dual targeting of membrane-associated profilin 1 and phosphatidylethanolamine by Di Liu (30843)

“…<p>African swine fever (ASF) is a highly contagious disease caused by African swine fever virus (ASFV), posing a serious threat to the global pig industry. Natural small molecules have been reported to exhibit anti-ASFV potential. …”

Data Sheet 1_The global, regional, and national impact of laryngeal cancer from 1990 to 2021, along with forecasts for 2050: a comprehensive analysis for the Global Burden of Disea... by Tingting Duan (5181482)

“…In high SDI regions, the disease burden gradually decreases after reaching its peak, while in low SDI regions, the reduction or increase in the disease burden is relatively small. …”

Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf by Faruk Hossen (20275670)

“…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …”

Data Sheet 1_Succinic acid improves crop chemical components by regulating soil chemical properties, microbes and metabolites.docx by Dian-long Li (22465567)

“…Introduction<p>Small molecule metabolites can act as soil conditioners to improve the soil environment and thereby promote crop growth. …”

Data Sheet 1_Application of compost amended with biochar on the distribution of antibiotic resistance genes in a soil–cucumber system—from the perspective of high-dose fertilizatio... by Shuai Shi (333614)

“…Compared with those in the control treatment group, the absolute abundance of ermB, ermT, gyrA, qnrS, tetC, and intI1 decreased by 6–100% in the soil of the SBTC group. …”

Global incidence of female birdsong is predicted by territoriality and biparental care in songbirds by Karan J. Odom (9719358)

“…Daily nest predation rates decrease with body size in passerine birds. The American Naturalist, 196, 743-754. (2) life- and natural history traits from Dale et al. 2015: Dale, J., Dey, C. …”

Data from The impact of human disturbances on the regeneration layer of tropical rainforests by Ricard Arasa-Gisbert (20308659)

“…The Hedges’ g index estimates the standardized mean difference and variance between a control and treatment sites and can be used in studies with a small sample size (Gurevitch & Hedges, 1999). In particular, negative values of Hedges’ g indicate a decrease in the response variable (e.g., richness or abundance) in disturbed sites, whereas positive values indicate the opposite. …”

Benzofuranyl-pyrazole as a Novel Scaffold for <i>In Vitro</i> and <i>In Vivo</i> Potent Anticancer Therapeutics That Directly Disrupt the ‘Undruggable’ MYC Oncogene and Potentiate... by Liuqing Yang (128705)

“…Meanwhile, it synergized with a small-molecule immune checkpoint inhibitor <i>in vivo</i>, highlighting its potential application in immunotherapy.…”

Image 4_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg by Zexin Zhang (7507979)

“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”

Data Sheet 1_Biorefinery—inspired, two-step valorization strategy to manage plant-based recalcitrant organic waste, involving solvent extraction, and fermentation with Bacillus cla... by Sreejith Meppoyilam (20563139)

“…This novel two-step valorization workflow involves the extraction of small molecules using organic solvents, and fermentation of resulting denatured residues (increased biodegradability or decreased recalcitrance) of reduced microbial load. …”

Table 5_Characteristics of pediatric interventional drug trials registered between 2015 and 2024 on ClinicalTrials.gov.docx by Yinghong Zhou (6873053)

“…</p>Conclusion<p>In the last ten years, registered pediatric drug trials have either stayed stable or slightly decreased, often featuring small sample sizes and rarely using age-specific formulations. …”

Reconciliation services product value analysis. by Yu Zhang (12946)

“…Rational selection and breeding of economic forest species aid in creating ecolabel brands. This small - watershed - scale analysis improves the accuracy of assessing ecological and economic development in karst areas, providing a scientific basis for decision - making to strengthen ecological restoration and enhance people’s well - being.…”

Data Sheet 2_UrbanAgri: a transfer learning-based plant stress identification framework for sustainable smart urban growth.pdf by Upinder Kaur (10805317)

“…<p>The speed of urbanization around the world is decreasing the arable land endangering food security since the population is estimated to reach 9.7 billion by the year 2050. …”

Table 1_Defining the end of puberty in boys: INSL3 and the acute determinants of adult Leydig-cell functional capacity.docx by Bilal Tulumcu (21428903)

“…</p>Results and discussion<p>At 17 years, mean INSL3 is not yet maximal, with high variance due to both longitudinal (timing of pubertal trajectory) and cross-sectional influences, whereas at 24 years, circulating INSL3 concentration has stabilized to its final adult status, even showing a small decreasing trend with age. Maximal INSL3 (i.e., peak puberty) was calculated to be at approximately 22 years in this cohort. …”

Means of sampling data in the Shibing study area. by Yu Zhang (12946)

“…Rational selection and breeding of economic forest species aid in creating ecolabel brands. This small - watershed - scale analysis improves the accuracy of assessing ecological and economic development in karst areas, providing a scientific basis for decision - making to strengthen ecological restoration and enhance people’s well - being.…”

Technology roadmap. by Yu Zhang (12946)

“…Rational selection and breeding of economic forest species aid in creating ecolabel brands. This small - watershed - scale analysis improves the accuracy of assessing ecological and economic development in karst areas, providing a scientific basis for decision - making to strengthen ecological restoration and enhance people’s well - being.…”

Image 3_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif by Zechen Zhang (11702123)

“…C-terminal telopeptide (CTX) showed a small, statistically significant reduction (MD −0.09, 95% CI −0.14 to −0.05) with uncertain clinical relevance. …”