Table 5_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx حسب Jiayue Zhang (7832669)

"…</p>Results<p>The global all-age disability-adjusted life year (DALY) rate of ischemic stroke decreased by 34.90% between 1990 and 2021, with the highest disease burden in China, especially in males. …"

Table 2_Epidemiological trends and disparities in iodine, vitamin A, and iron deficiencies among children aged 0–14 years globally, 1990–2021.docx حسب Fang Peng (327071)

"…Vitamin A deficiency incidence rate decreased by 94.9% (EAPC: −2.02), while DALY rates fell 92.8%. …"

Table_2_Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease.docx حسب Rui Zhu (305217)

"…</p>Results<p>Compared with the HCs, NIID patients showed reduced mean kurtosis (MK), radial kurtosis (RK), axial kurtosis (AK), and kurtosis fractional anisotropy (KFA) values in deep gray matter regions. Significantly decreased MK, RK, AK, KFA and fractional anisotropy (FA), and increased mean diffusivity (MD) values were observed in extensive white matter fiber tracts. …"

Image 3_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... حسب Xuewen Rong (6242657)

"…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…"

<b>Does long term fertilization impact soil carbon’s functional group composition and its distribution in aggregates?</b> حسب Prabhsimran Singh (20789675)

"…Long-term use of 100% NPK+FYM significantly increased SOC by 150%, even in deeper layers. …"

Image 2_A nomogram model to predict the high risk of lower live birth probability in young women undergoing the first IVF-ET cycle: a retrospective study.tif حسب Chang Liu (35901)

"…This nomogram offers a practical and accurate tool for early identification of young women with potentially decreased ovarian reserve, enabling timely intervention and personalized management strategies.…"

Image 1_Neuroimaging and molecular mechanism of action of Cang-ai volatile oil in the treatment of vascular cognitive impairment.tif حسب Bojun Chen (317487)

"…</p>Conclusion<p>This study demonstrates that CAVO therapy reduces inflammatory responses in brain regions of VCI rats, decreases apoptosis and necrosis, protects neurons in affected areas, and simultaneously enhances functional connectivity strength between brain regions in VCI rats, thereby exerting a cognitive-improving effect on VCI.…"

DataSheet1_Predicting the solubility of CO2 and N2 in ionic liquids based on COSMO-RS and machine learning.docx حسب Hongling Qin (5557505)

"…The results show that the COSMO-RS with correction can significantly improve the prediction of CO₂ solubility, and the corresponding average absolute relative deviation (AARD) is decreased from 43.4% to 11.9%. …"

Table 2_CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salinity conditions in quinoa.xlsx حسب Yasufumi Kobayashi (5481530)

"…By contrast, K⁺ accumulation was slightly reduced in the aerial parts but significantly decreased in the roots of all the genotypes. …"

Data Sheet 1_Deglycosylated azithromycin alleviates cisplatin-evoked constipation in mice by altering host metabolome and gut microbiota composition.docx حسب Xiaoting Gu (3368495)

"…</p>Results<p>Deg-AZM significantly enhanced intestinal motility in the mice with cisplatin-evoked constipation. …"

Table 1_Transcriptional patterns of brain structural abnormalities in CSVD-related cognitive impairment.docx حسب Haixia Mao (3775582)

"…Furthermore, a total of 1,580 genes were revealed to be significantly associated with regional change in GMV. …"

Image 1_Resveratrol and β-hydroxy-β-methylbutyric acid supplementation promotes ileal development and digestive function by altering microbial community abundance and metabolites i... حسب Jiacheng Gan (20413847)

"…</p>Results<p>Results indicated that dietary RES and (or) HMB supplementation significantly improved the phenotype (mucosal thickness and villus width), SCFAs concentrations, and digestive enzymes (lipase, cellulase, and α-amylase) (p < 0.05). …"

Image 1_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.pdf حسب Yuanbing Zhu (20538638)

"…Differential gene expression and immune infiltration analysis showed that upstream transcription factors, including Forkhead box P3 (FOXP3), were significantly disrupted. In vitro cytology experiments, the results indicate that SIRT1 is activated in LPS induced inflammation, subsequently perturbing the Treg/Th17 immune balance axis. …"

Table 1_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... حسب Xuewen Rong (6242657)

"…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…"

Trends and Disparities in Rates of Hypoglycemia Among Hospitalized Patients with Type II Diabetes حسب Paul A Heidenreich (13188712)

"…</p><p dir="ltr">Results: Among 512,261 patients hospitalized with diabetes, 6.8% (34,918) had an episode of hypoglycemia (< 70 mg/dl). This rate decreased by 17% from 2016-2022 (7.4% to 6.3%) while the rate of discharge diagnosis among those with hypoglycemia increased. …"

Data Sheet 1_Aperiodic brain activity changes in patients with stroke following virtual reality-based upper limb robotic rehabilitation: a pilot Randomized Controlled Trial.docx حسب Maria Cristina Mauro (22449604)

"…At T2, the SEI in the AH decreased again and was lower than in the UH. No differences were found between unilateral and bilateral groups.…"

Table 1_The CD300c antibody CL7 suppresses tumor growth by regulating the tumor microenvironment in non-small cell lung carcinoma.docx حسب Soyoung Kim (117362)

"…Only representative data from the 10 mg/kg CL7 group are shown to maintain consistency with subsequent analyses (flow cytometry, RT-qPCR, and IHC). Tumor growth was significantly suppressed in the CL7-treated group compared to the PBS control group. …"

Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke حسب Yike Wu (20982007)

"…Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …"

S2 File - حسب Jinfeng Zhao (142391)

"…Exposure to aerobic exercise for 12 weeks significantly improved renal fibrosis and alleviated the intrarenal genetic alterations induced by aging. …"

Long-term outcomes of refractory central venous occlusive disease treated by stent deployment in patients undergoing maintenance hemodialysis حسب Yuqin Xiong (14291305)

"…The number of secondary stenting procedures was significantly associated with decreased VA abandonment [odds ratio (OR) = 0.089, 95% confidence interval (CI): 0.008–0.992, <i>p</i> = 0.049] and all-cause mortality (OR = 0.104, 95% CI: 0.011–0.947, <i>p</i> = 0.045).…"